Gene Review:
Il21r - interleukin 21 receptor
Mus musculus
Synonyms:
IL-21 receptor, IL-21R, Interleukin-21 receptor, LR-beta, Lymphocyte receptor beta, ...
- The IL-21 receptor augments Th2 effector function and alternative macrophage activation. Pesce, J., Kaviratne, M., Ramalingam, T.R., Thompson, R.W., Urban, J.F., Cheever, A.W., Young, D.A., Collins, M., Grusby, M.J., Wynn, T.A. J. Clin. Invest. (2006)
- The common gamma chain (gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-induced cell proliferation via JAK3. Habib, T., Senadheera, S., Weinberg, K., Kaushansky, K. Biochemistry (2002)
- A critical role for IL-21 in regulating immunoglobulin production. Ozaki, K., Spolski, R., Feng, C.G., Qi, C.F., Cheng, J., Sher, A., Morse, H.C., Liu, C., Schwartzberg, P.L., Leonard, W.J. Science (2002)
- Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis. Distler, J.H., Jüngel, A., Kowal-Bielecka, O., Michel, B.A., Gay, R.E., Sprott, H., Matucci-Cerinic, M., Chilla, M., Reich, K., Kalden, J.R., Müller-Ladner, U., Lorenz, H.M., Gay, S., Distler, O. Arthritis Rheum. (2005)
- Alterations of expression of developmentally important genes in preimplantation bovine embryos by in vitro culture conditions: implications for subsequent development. Niemann, H., Wrenzycki, C. Theriogenology (2000)
- IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity. Kasaian, M.T., Whitters, M.J., Carter, L.L., Lowe, L.D., Jussif, J.M., Deng, B., Johnson, K.A., Witek, J.S., Senices, M., Konz, R.F., Wurster, A.L., Donaldson, D.D., Collins, M., Young, D.A., Grusby, M.J. Immunity (2002)
- Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. Zeng, R., Spolski, R., Finkelstein, S.E., Oh, S., Kovanen, P.E., Hinrichs, C.S., Pise-Masison, C.A., Radonovich, M.F., Brady, J.N., Restifo, N.P., Berzofsky, J.A., Leonard, W.J. J. Exp. Med. (2005)
- Cloning of a type I cytokine receptor most related to the IL-2 receptor beta chain. Ozaki, K., Kikly, K., Michalovich, D., Young, P.R., Leonard, W.J. Proc. Natl. Acad. Sci. U.S.A. (2000)
- IL-21 induces the apoptosis of resting and activated primary B cells. Mehta, D.S., Wurster, A.L., Whitters, M.J., Young, D.A., Collins, M., Grusby, M.J. J. Immunol. (2003)
- Redundant and unique regulation of activated mouse B lymphocytes by IL-4 and IL-21. Jin, H., Malek, T.R. J. Leukoc. Biol. (2006)
- mRNA expression of leukaemia inhibitory factor (LIF) and its receptor subunits glycoprotein 130 and LIF-receptor-beta in bovine embryos derived in vitro or in vivo. Eckert, J., Niemann, H. Mol. Hum. Reprod. (1998)
- Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis. Jin, H., Carrio, R., Yu, A., Malek, T.R. J. Immunol. (2004)
- Interleukin-21 and the IL-21 receptor: novel effectors of NK and T cell responses. Parrish-Novak, J., Foster, D.C., Holly, R.D., Clegg, C.H. J. Leukoc. Biol. (2002)
- Interleukin-21 inhibits dendritic cell-mediated T cell activation and induction of contact hypersensitivity in vivo. Brandt, K., Bulfone-Paus, S., Jenckel, A., Foster, D.C., Paus, R., Rückert, R. J. Invest. Dermatol. (2003)
- Expression of interleukin-21 receptor, but not interleukin-21, in synovial fibroblasts and synovial macrophages of patients with rheumatoid arthritis. Jüngel, A., Distler, J.H., Kurowska-Stolarska, M., Seemayer, C.A., Seibl, R., Forster, A., Michel, B.A., Gay, R.E., Emmrich, F., Gay, S., Distler, O. Arthritis Rheum. (2004)
- Biology of IL-21 and the IL-21 receptor. Mehta, D.S., Wurster, A.L., Grusby, M.J. Immunol. Rev. (2004)