The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Enzootic Bovine Leukosis

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Enzootic Bovine Leukosis

  • A procedure was developed to isolate a glycoprotein with precipitating antigen activity from fluids from fetal lamb kidney cell cultures persistently infected with bovine leukemia virus (BLV) [1].
  • Strongest cross-reactivity was detected between HTLV-III/LAV pol- and gag- genes and STLV-IIIAGM, whereas no cross-reactivity was detected between STLV-IIIAGM and molecular clones of human T-lymphotropic virus types I and II (HTLV-I and -II), visna virus, bovine leukemia virus, or feline leukemia virus [2].
  • Interleukin-12 p40 mRNA expression in bovine leukemia virus-infected animals: increase in alymphocytosis but decrease in persistent lymphocytosis [3].
  • Sera obtained from 100% of cattle examined with clinically diagnosed lymphosarcoma contained high-titered antibody to 125I-labeled bovine leukemia virus glycoprotein, whereas sera from animals in a disease-free herd were antibody negative [4].
  • In vitro detection of a specific complex of the bovine leukemia virus (BLV) MA(p15) protein and the 5'-terminal RNA dimer led to the hypothesis that the NH2-terminal domain of retrovirus gag protein precursor is involved in the selective viral RNA packaging mechanism [5].

High impact information on Enzootic Bovine Leukosis


Chemical compound and disease context of Enzootic Bovine Leukosis


Biological context of Enzootic Bovine Leukosis


Anatomical context of Enzootic Bovine Leukosis


Gene context of Enzootic Bovine Leukosis


Analytical, diagnostic and therapeutic context of Enzootic Bovine Leukosis


  1. Isolation of a precipitating glycoprotein antigen from cell cultures persistently infected with bovine leukemia virus. Phillips, M., Miller, J.M., Van Der Maaten, M.J. J. Natl. Cancer Inst. (1978) [Pubmed]
  2. Cross-reactivity to human T-lymphotropic virus type III/lymphadenopathy-associated virus and molecular cloning of simian T-cell lymphotropic virus type III from African green monkeys. Hirsch, V., Riedel, N., Kornfeld, H., Kanki, P.J., Essex, M., Mullins, J.I. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
  3. Interleukin-12 p40 mRNA expression in bovine leukemia virus-infected animals: increase in alymphocytosis but decrease in persistent lymphocytosis. Pyeon, D., Splitter, G.A. J. Virol. (1998) [Pubmed]
  4. Biochemical and immunological characterization of the major envelope glycoprotein of bovine leukemia virus. Devare, S.G., Stephenson, J.R. J. Virol. (1977) [Pubmed]
  5. Bovine leukemia virus RNA sequences involved in dimerization and specific gag protein binding: close relation to the packaging sites of avian, murine, and human retroviruses. Katoh, I., Yasunaga, T., Yoshinaka, Y. J. Virol. (1993) [Pubmed]
  6. Bovine leukemia virus: an exogenous RNA oncogenic virus. Kettmann, R., Portetelle, D., Mammerickx, M., Cleuter, Y., Dekegel, D., Galoux, M., Ghysdael, J., Burny, A., Chantrenne, H. Proc. Natl. Acad. Sci. U.S.A. (1976) [Pubmed]
  7. Inhibition of the reverse transcriptase of bovine leukemia virus by antibody in sera from leukemic cattle and immunological characterization of the enzyme. Wuu, K.D., Graves, D.C., Ferrer, J.F. Cancer Res. (1977) [Pubmed]
  8. In vitro transmission and propagation of the bovine leukemia virus in monolayer cell cultures. Graves, D.C., Ferrer, J.F. Cancer Res. (1976) [Pubmed]
  9. Inhibition of mammalian polyadenylate polymerase by 2-aza-1,N6-etheno-adenosine triphosphate. Keshgegian, A.A., Tsou, K.C., Furth, J.J. Cancer Res. (1976) [Pubmed]
  10. Poly (A) polymerase of bovine lymphosarcoma. Keshgegian, A.A., Meltzer, S.M., Furth, J.J. Cancer Res. (1975) [Pubmed]
  11. RNA polymerase isolated from bovine lymphosarcoma by sequential low- and high-salt extraction. Keshgegian, A.A., Austin, G.E., Meltzer, S.M., Furth, J.J. Cancer Res. (1975) [Pubmed]
  12. The amino acid (157-197) peptide segment of bovine leukemia virus p34tax encompass a leucine-rich globally neutral activation domain. Willems, L., Kettmann, R., Burny, A. Oncogene (1991) [Pubmed]
  13. Dileucine and YXXL motifs in the cytoplasmic tail of the bovine leukemia virus transmembrane envelope protein affect protein expression on the cell surface. Novakovic, S., Sawai, E.T., Radke, K. J. Virol. (2004) [Pubmed]
  14. Involvement of the cyclic AMP-responsive element binding protein in bovine leukemia virus expression in vivo. Adam, E., Kerkhofs, P., Mammerickx, M., Kettmann, R., Burny, A., Droogmans, L., Willems, L. J. Virol. (1994) [Pubmed]
  15. In vivo study of genetically simplified bovine leukemia virus derivatives that lack tax and rex. Boris-Lawrie, K., Altanerova, V., Altaner, C., Kucerova, L., Temin, H.M. J. Virol. (1997) [Pubmed]
  16. Involvement of glutathione as a mechanism of indirect protection against spontaneous ex vivo apoptosis associated with bovine leukemia virus. Sanchez Alcaraz, T., Kerkhofs, P., Reichert, M., Kettmann, R., Willems, L. J. Virol. (2004) [Pubmed]
  17. Role of the proline-rich motif of bovine leukemia virus transmembrane protein gp30 in viral load and pathogenicity in sheep. Reichert, M., Winnicka, A., Willems, L., Kettmann, R., Cantor, G.H. J. Virol. (2001) [Pubmed]
  18. Point mutation of p53 tumor suppressor gene in bovine leukemia virus-induced lymphosarcoma. Zhuang, W., Tajima, S., Okada, K., Ikawa, Y., Aida, Y. Leukemia (1997) [Pubmed]
  19. A highly efficient method for the site-specific integration of transfected plasmids into the genome of mammalian cells using purified retroviral integrase. Tanaka, A.S., Tanaka, M., Komuro, K. Gene (1998) [Pubmed]
  20. B-lymphocyte proliferation during bovine leukemia virus-induced persistent lymphocytosis is enhanced by T-lymphocyte-derived interleukin-2. Trueblood, E.S., Brown, W.C., Palmer, G.H., Davis, W.C., Stone, D.M., McElwain, T.F. J. Virol. (1998) [Pubmed]
  21. Oncoviral bovine leukemia virus G4 and human T-cell leukemia virus type 1 p13(II) accessory proteins interact with farnesyl pyrophosphate synthetase. Lefèbvre, L., Vanderplasschen, A., Ciminale, V., Heremans, H., Dangoisse, O., Jauniaux, J.C., Toussaint, J.F., Zelnik, V., Burny, A., Kettmann, R., Willems, L. J. Virol. (2002) [Pubmed]
  22. Human T-cell leukemia virus type I: induction of syncytia and inhibition by patients' sera. Nagy, K., Clapham, P., Cheingsong-Popov, R., Weiss, R.A. Int. J. Cancer (1983) [Pubmed]
  23. Altered interleukin-2 production by lymphocyte populations from bovine leukemia virus-infected cattle. Sordillo, L.M., Hicks, C.R., Pighetti, G.M. Proc. Soc. Exp. Biol. Med. (1994) [Pubmed]
  24. Phenotypic characterization of bovine lymphoblastoid cell lines. Romano, M.J., Stewart, J.A., Lewin, H.A. Vet. Immunol. Immunopathol. (1989) [Pubmed]
  25. The mouse homolog of the bovine leukemia virus receptor is closely related to the delta subunit of adaptor-related protein complex AP-3, not associated with the cell surface. Suzuki, T., Ikeda, H. J. Virol. (1998) [Pubmed]
  26. Isolation and characterisation of a bovine cDNA encoding eukaryotic initiation factor 2 alpha. Green, S.R., Fullekrug, J., Sauer, K., Tuite, M.F. Biochim. Biophys. Acta (1991) [Pubmed]
  27. Bovine leukemia virus transmembrane protein gp30 physically associates with the down-regulatory phosphatase SHP-1. Cantor, G.H., Pritchard, S.M., Orlik, O., Splitter, G.A., Davis, W.C., Reeves, R. Cell. Immunol. (1999) [Pubmed]
  28. Lack of mutation in the WAF1/CIP1 gene during bovine leukemia virus-induced leukemogenesis. Dequiedt, F., Willems, L., Kerkhofs, P., Burny, A., Kettmann, R. Vet. Immunol. Immunopathol. (1997) [Pubmed]
  29. Changes in antibody titers in cattle infected clinically and subclinically with bovine leukemia virus. Kono, Y., Sentsui, H., Miyamoto, T., Morozumi, K., Sakamoto, Y. Int. J. Cancer (1982) [Pubmed]
  30. Iodoacetamide treatment of bovine leukemia virus glycoprotein gp51 enhances the western blotting reactivity of anti-peptide antibodies. Callebaut, I., Burny, A., Portetelle, D. FEBS Lett. (1991) [Pubmed]
  31. Microplate enzyme-linked immunosorbent assay for bovine leukemia virus antibody. Poli, G., Balsari, A., Toniolo, A., Ponti, W., Vacirca, G. J. Clin. Microbiol. (1981) [Pubmed]
  32. Vaccination of cattle with binary ethylenimine-treated bovine leukemia virus. Miller, J.M., Van der Maaten, M.J., Schmerr, M.J. Am. J. Vet. Res. (1983) [Pubmed]
  33. Proliferating cell nuclear antigen expression in sheep infected with bovine leukemia virus. Hailata, N., Johnson, R., al-Bagdadi, F., Hanash, S. Vet. Immunol. Immunopathol. (1995) [Pubmed]
WikiGenes - Universities