Gene Review:
TRPM8 - transient receptor potential cation...
Homo sapiens
Synonyms:
LTRPC6, LTrpC-6, LTrpC6, Long transient receptor potential channel 6, TRPP8, ...
- Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells. Thebault, S., Lemonnier, L., Bidaux, G., Flourakis, M., Bavencoffe, A., Gordienko, D., Roudbaraki, M., Delcourt, P., Panchin, Y., Shuba, Y., Skryma, R., Prevarskaya, N. J. Biol. Chem. (2005)
- TRPA1 and TRPM8 activation in humans: effects of cinnamaldehyde and menthol. Namer, B., Seifert, F., Handwerker, H.O., Maihöfner, C. Neuroreport (2005)
- Noxious cold stimulation induces mitogen-activated protein kinase activation in transient receptor potential (TRP) channels TRPA1- and TRPM8-containing small sensory neurons. Mizushima, T., Obata, K., Katsura, H., Yamanaka, H., Kobayashi, K., Dai, Y., Fukuoka, T., Tokunaga, A., Mashimo, T., Noguchi, K. Neuroscience (2006)
- A TRP channel that senses cold stimuli and menthol. Peier, A.M., Moqrich, A., Hergarden, A.C., Reeve, A.J., Andersson, D.A., Story, G.M., Earley, T.J., Dragoni, I., McIntyre, P., Bevan, S., Patapoutian, A. Cell (2002)
- High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol. Bandell, M., Dubin, A.E., Petrus, M.J., Orth, A., Mathur, J., Hwang, S.W., Patapoutian, A. Nat. Neurosci. (2006)
- Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Bandell, M., Story, G.M., Hwang, S.W., Viswanath, V., Eid, S.R., Petrus, M.J., Earley, T.J., Patapoutian, A. Neuron (2004)
- Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells. Zhang, L., Barritt, G.J. Cancer Res. (2004)
- Evidence for specific TRPM8 expression in human prostate secretory epithelial cells: functional androgen receptor requirement. Bidaux, G., Roudbaraki, M., Merle, C., Crépin, A., Delcourt, P., Slomianny, C., Thebault, S., Bonnal, J.L., Benahmed, M., Cabon, F., Mauroy, B., Prevarskaya, N. Endocr. Relat. Cancer (2005)
- The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Voets, T., Droogmans, G., Wissenbach, U., Janssens, A., Flockerzi, V., Nilius, B. Nature (2004)
- Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid. Kraft, R., Grimm, C., Frenzel, H., Harteneck, C. Br. J. Pharmacol. (2006)
- Cool (TRPM8) and hot (TRPV1) receptors in the bladder and male genital tract. Stein, R.J., Santos, S., Nagatomi, J., Hayashi, Y., Minnery, B.S., Xavier, M., Patel, A.S., Nelson, J.B., Futrell, W.J., Yoshimura, N., Chancellor, M.B., De Miguel, F. J. Urol. (2004)
- Bisandrographolide from Andrographis paniculata Activates TRPV4 Channels. Smith, P.L., Maloney, K.N., Pothen, R.G., Clardy, J., Clapham, D.E. J. Biol. Chem. (2006)
- Conservation of functional and pharmacological properties in the distantly related temperature sensors TRVP1 and TRPM8. Weil, A., Moore, S.E., Waite, N.J., Randall, A., Gunthorpe, M.J. Mol. Pharmacol. (2005)
- Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate. Benedikt, J., Teisinger, J., Vyklicky, L., Vlachova, V. J. Neurochem. (2007)
- TRPM8 protein localization in trigeminal ganglion and taste papillae. Abe, J., Hosokawa, H., Okazawa, M., Kandachi, M., Sawada, Y., Yamanaka, K., Matsumura, K., Kobayashi, S. Brain Res. Mol. Brain Res. (2005)
- 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. Hu, H.Z., Gu, Q., Wang, C., Colton, C.K., Tang, J., Kinoshita-Kawada, M., Lee, L.Y., Wood, J.D., Zhu, M.X. J. Biol. Chem. (2004)
- Thermosensation and pain. Tominaga, M., Caterina, M.J. J. Neurobiol. (2004)
- Thermal gating of TRP ion channels: food for thought? Liman, E.R. Sci. STKE (2006)
- Biophysical properties of menthol-activated cold receptor TRPM8 channels. Hui, K., Guo, Y., Feng, Z.P. Biochem. Biophys. Res. Commun. (2005)
- Heat-evoked activation of the ion channel, TRPV4. Güler, A.D., Lee, H., Iida, T., Shimizu, I., Tominaga, M., Caterina, M. J. Neurosci. (2002)
- Thermosensitive transient receptor potential channels in vagal afferent neurons of the mouse. Zhang, L., Jones, S., Brody, K., Costa, M., Brookes, S.J. Am. J. Physiol. Gastrointest. Liver Physiol. (2004)
- Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain. Proudfoot, C.J., Garry, E.M., Cottrell, D.F., Rosie, R., Anderson, H., Robertson, D.C., Fleetwood-Walker, S.M., Mitchell, R. Curr. Biol. (2006)