Gene Review:
Abcb11 - ATP-binding cassette, subfamily B...
Rattus norvegicus
Synonyms:
ATP-binding cassette sub-family B member 11, Bile salt export pump, Bsep, Sister of P-glycoprotein, Spgp
- Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase. Kubitz, R., Sütfels, G., Kühlkamp, T., Kölling, R., Häussinger, D. Gastroenterology (2004)
- Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate. Funk, C., Pantze, M., Jehle, L., Ponelle, C., Scheuermann, G., Lazendic, M., Gasser, R. Toxicology (2001)
- Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats. van Waarde, W.M., Verkade, H.J., Wolters, H., Havinga, R., Baller, J., Bloks, V., Müller, M., Sauer, P.J., Kuipers, F. Gastroenterology (2002)
- Heat stress prevents impairment of bile acid transport in endotoxemic rats by a posttranscriptional mechanism. Bolder, U., Schmidt, A., Landmann, L., Kidder, V., Tange, S., Jauch, K.W. Gastroenterology (2002)
- Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver. Stieger, B., Fattinger, K., Madon, J., Kullak-Ublick, G.A., Meier, P.J. Gastroenterology (2000)
- Taurine supplementation induces multidrug resistance protein 2 and bile salt export pump expression in rats and prevents endotoxin-induced cholestasis. Mühlfeld, A., Kubitz, R., Dransfeld, O., Häussinger, D., Wettstein, M. Arch. Biochem. Biophys. (2003)
- Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat. Crocenzi, F.A., Mottino, A.D., Sánchez Pozzi, E.J., Pellegrino, J.M., Rodríguez Garay, E.A., Milkiewicz, P., Vore, M., Coleman, R., Roma, M.G. Gut (2003)
- Differential regulation of hepatic bile salt and organic anion transporters in pregnant and postpartum rats and the role of prolactin. Cao, J., Huang, L., Liu, Y., Hoffman, T., Stieger, B., Meier, P.J., Vore, M. Hepatology (2001)
- Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes. Rippin, S.J., Hagenbuch, B., Meier, P.J., Stieger, B. Hepatology (2001)
- Mechanisms involved in spironolactone-induced choleresis in the rat. Role of multidrug resistance-associated protein 2. Ruiz, M.L., Villanueva, S.S., Luquita, M.G., Sánchez-Pozzi, E.J., Crocenzi, F.A., Pellegrino, J.M., Ochoa, J.E., Vore, M., Mottino, A.D., Catania, V.A. Biochem. Pharmacol. (2005)
- Differential developmental regulation of rat liver canalicular membrane transporters Bsep and Mrp2. Tomer, G., Ananthanarayanan, M., Weymann, A., Balasubramanian, N., Suchy, F.J. Pediatr. Res. (2003)
- Functional analysis of the rat bile salt export pump gene promoter. Gerloff, T., Geier, A., Roots, I., Meier, P.J., Gartung, C. Eur. J. Biochem. (2002)
- Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity. Schmitt, M., Kubitz, R., Lizun, S., Wettstein, M., Häussinger, D. Hepatology (2001)
- Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat. Funk, C., Ponelle, C., Scheuermann, G., Pantze, M. Mol. Pharmacol. (2001)
- Different pathways of canalicular secretion of sulfated and non-sulfated fluorescent bile acids: a study in isolated hepatocyte couplets and TR- rats. Mills, C.O., Milkiewicz, P., Müller, M., Roma, M.G., Havinga, R., Coleman, R., Kuipers, F., Jansen, P.L., Elias, E. J. Hepatol. (1999)
- Tauroursodeoxycholic acid inserts the bile salt export pump into canalicular membranes of cholestatic rat liver. Dombrowski, F., Stieger, B., Beuers, U. Lab. Invest. (2006)
- Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate. Bode, K.A., Donner, M.G., Leier, I., Keppler, D. Biochem. Pharmacol. (2002)
- Silibinin prevents cholestasis-associated retrieval of the bile salt export pump, Bsep, in isolated rat hepatocyte couplets: possible involvement of cAMP. Crocenzi, F.A., Basiglio, C.L., Pérez, L.M., Portesio, M.S., Pozzi, E.J., Roma, M.G. Biochem. Pharmacol. (2005)
- Estradiol-17beta-D-glucuronide induces endocytic internalization of Bsep in rats. Crocenzi, F.A., Mottino, A.D., Cao, J., Veggi, L.M., Pozzi, E.J., Vore, M., Coleman, R., Roma, M.G. Am. J. Physiol. Gastrointest. Liver Physiol. (2003)
- Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver. Gerloff, T., Geier, A., Stieger, B., Hagenbuch, B., Meier, P.J., Matern, S., Gartung, C. Gastroenterology (1999)
- Heat stress enhances recovery of hepatocyte bile acid and organic anion transporters in endotoxemic rats by multiple mechanisms. Bolder, U., Jeschke, M.G., Landmann, L., Wolf, F., de Sousa, C., Schlitt, H.J., Przkora, R. Cell Stress Chaperones (2006)