Gene Review:
Abcb11 - ATP-binding cassette, sub-family B...
Mus musculus
Synonyms:
ABC16, ATP-binding cassette sub-family B member 11, Bile salt export pump, Bsep, Lith1, ...
- Mice overexpressing hepatic Abcb11 rapidly develop cholesterol gallstones. Henkel, A., Wei, Z., Cohen, D.E., Green, R.M. Mamm. Genome (2005)
- Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice. Lam, P., Wang, R., Ling, V. Biochemistry (2005)
- Hepatic canalicular membrane transport of bile salt in C57L/J and AKR/J mice: implications for cholesterol gallstone formation. Hoda, F., Green, R.M. J. Membr. Biol. (2003)
- Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis. Wang, R., Salem, M., Yousef, I.M., Tuchweber, B., Lam, P., Childs, S.J., Helgason, C.D., Ackerley, C., Phillips, M.J., Ling, V. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine. Zollner, G., Fickert, P., Fuchsbichler, A., Silbert, D., Wagner, M., Arbeiter, S., Gonzalez, F.J., Marschall, H.U., Zatloukal, K., Denk, H., Trauner, M. J. Hepatol. (2003)
- Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. Wagner, M., Fickert, P., Zollner, G., Fuchsbichler, A., Silbert, D., Tsybrovskyy, O., Zatloukal, K., Guo, G.L., Schuetz, J.D., Gonzalez, F.J., Marschall, H.U., Denk, H., Trauner, M. Gastroenterology (2003)
- Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis. Hays, T., Rusyn, I., Burns, A.M., Kennett, M.J., Ward, J.M., Gonzalez, F.J., Peters, J.M. Carcinogenesis (2005)
- Lith6: a new QTL for cholesterol gallstones from an intercross of CAST/Ei and DBA/2J inbred mouse strains. Lyons, M.A., Wittenburg, H., Li, R., Walsh, K.A., Leonard, M.R., Korstanje, R., Churchill, G.A., Carey, M.C., Paigen, B. J. Lipid Res. (2003)
- Cholelithiasis: genetic hypothesis. Sanchez-Mete, L., Attili, A.F. Minerva gastroenterologica e dietologica. (2000)
- Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein. Wang, R., Lam, P., Liu, L., Forrest, D., Yousef, I.M., Mignault, D., Phillips, M.J., Ling, V. Hepatology (2003)
- Ursodeoxycholic acid (UDCA) prevents DCA effects on male mouse liver via up-regulation of CYP [correction of CXP] and preservation of BSEP activities. Paolini, M., Pozzetti, L., Montagnani, M., Potenza, G., Sabatini, L., Antelli, A., Cantelli-Forti, G., Roda, A. Hepatology (2002)
- Cholemic transgenic mice: a novel animal model to investigate the effects of bile acids. Ljubuncic, P., Yousef, I., Bomzon, A. Journal of pharmacological and toxicological methods. (2004)
- Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice. Erickson, S.K., Lear, S.R., Deane, S., Dubrac, S., Huling, S.L., Nguyen, L., Bollineni, J.S., Shefer, S., Hyogo, H., Cohen, D.E., Shneider, B., Sehayek, E., Ananthanarayanan, M., Balasubramaniyan, N., Suchy, F.J., Batta, A.K., Salen, G. J. Lipid Res. (2003)
- Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: integrated activities of hepatic lipid regulatory enzymes. Lammert, F., Wang, D.Q., Paigen, B., Carey, M.C. J. Lipid Res. (1999)
- Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. Lecureur, V., Sun, D., Hargrove, P., Schuetz, E.G., Kim, R.B., Lan, L.B., Schuetz, J.D. Mol. Pharmacol. (2000)
- Physiological characteristics of allo-cholic acid. Mendoza, M.E., Monte, M.J., Serrano, M.A., Pastor-Anglada, M., Stieger, B., Meier, P.J., Medarde, M., Marin, J.J. J. Lipid Res. (2003)
- Inflammatory cytokines, but not bile acids, regulate expression of murine hepatic anion transporters in endotoxemia. Hartmann, G., Cheung, A.K., Piquette-Miller, M. J. Pharmacol. Exp. Ther. (2002)
- Regulation of the hepatic multidrug resistance gene expression by endotoxin and inflammatory cytokines in mice. Hartmann, G., Kim, H., Piquette-Miller, M. Int. Immunopharmacol. (2001)
- Characterization of the mouse bile salt export pump overexpressed in the baculovirus system. Noe, J., Hagenbuch, B., Meier, P.J., St-Pierre, M.V. Hepatology (2001)
- Expression of liver plasma membrane transporters in gallstone-susceptible and gallstone-resistant mice. Müller, O., Schalla, C., Scheibner, J., Stange, E.F., Fuchs, M. Biochem. J. (2002)
- Hepatic overexpression of caveolins increases bile salt secretion in mice. Moreno, M., Molina, H., Amigo, L., Zanlungo, S., Arrese, M., Rigotti, A., Miquel, J.F. Hepatology (2003)
- Protective role of hydroxysteroid sulfotransferase in lithocholic acid-induced liver toxicity. Kitada, H., Miyata, M., Nakamura, T., Tozawa, A., Honma, W., Shimada, M., Nagata, K., Sinal, C.J., Guo, G.L., Gonzalez, F.J., Yamazoe, Y. J. Biol. Chem. (2003)
- Molecular cloning and characterization of the murine bile salt export pump. Green, R.M., Hoda, F., Ward, K.L. Gene (2000)
- High-resolution maps of the murine Chromosome 2 region containing the cholesterol gallstone locus, Lith1. Bouchard, G., Nelson, H.M., Lammert, F., Rowe, L.B., Carey, M.C., Paigen, B. Mamm. Genome (1999)