Gene Review:
GPAA1 - glycosylphosphatidylinositol anchor...
Homo sapiens
Synonyms:
GAA1, GAA1 protein homolog, GPI anchor attachment protein 1, Glycosylphosphatidylinositol anchor attachment 1 protein, hGAA1
- Increased expression of glycosyl-phosphatidylinositol anchor attachment protein 1 (GPAA1) is associated with gene amplification in hepatocellular carcinoma. Ho, J.C., Cheung, S.T., Patil, M., Chen, X., Fan, S.T. Int. J. Cancer (2006)
- GAAP-1: a transcriptional activator of p53 and IRF-1 possesses pro-apoptotic activity. Lallemand, C., Palmieri, M., Blanchard, B., Meritet, J.F., Tovey, M.G. EMBO Rep. (2002)
- Long-term efficacy after [E1-, polymerase-] adenovirus-mediated transfer of human acid-alpha-glucosidase gene into glycogen storage disease type II knockout mice. Ding, E.Y., Hodges, B.L., Hu, H., McVie-Wylie, A.J., Serra, D., Migone, F.K., Pressley, D., Chen, Y.T., Amalfitano, A. Hum. Gene Ther. (2001)
- Very late-onset Friedreich's ataxia with minimal GAA1 expansion mimicking multiple system atrophy of cerebellar type. Berciano, J., Infante, J., García, A., Polo, J.M., Volpini, V., Combarros, O. Mov. Disord. (2005)
- Identification of the base-pair substitution responsible for a human acid alpha glucosidase allele with lower "affinity" for glycogen (GAA 2) and transient gene expression in deficient cells. Martiniuk, F., Bodkin, M., Tzall, S., Hirschhorn, R. Am. J. Hum. Genet. (1990)
- Inositol deacylation of glycosylphosphatidylinositol-anchored proteins is mediated by mammalian PGAP1 and yeast Bst1p. Tanaka, S., Maeda, Y., Tashima, Y., Kinoshita, T. J. Biol. Chem. (2004)
- Glycophospholipid membrane anchor attachment. Molecular analysis of the cleavage/attachment site. Moran, P., Raab, H., Kohr, W.J., Caras, I.W. J. Biol. Chem. (1991)
- Intercellular transfer of the virally derived precursor form of acid alpha-glucosidase corrects the enzyme deficiency in inherited cardioskeletal myopathy Pompe disease. Pauly, D.F., Fraites, T.J., Toma, C., Bayes, H.S., Huie, M.L., Hirschhorn, R., Plotz, P.H., Raben, N., Kessler, P.D., Byrne, B.J. Hum. Gene Ther. (2001)
- Human and mouse GPAA1 (Glycosylphosphatidylinositol anchor attachment 1) genes: genomic structures, chromosome loci and the presence of a minor class intron. Inoue, N., Ohishi, K., Endo, Y., Fujita, T., Takeda, J., Kinoshita, T. Cytogenet. Cell Genet. (1999)
- Comparative efficiencies of C-terminal signals of native glycophosphatidylinositol (GPI)-anchored proproteins in conferring GPI-anchoring. Chen, R., Knez, J.J., Merrick, W.C., Medof, M.E. J. Cell. Biochem. (2001)
- Molecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteins. Hiroi, Y., Komuro, I., Chen, R., Hosoda, T., Mizuno, T., Kudoh, S., Georgescu, S.P., Medof, M.E., Yazaki, Y. FEBS Lett. (1998)
- Folate receptor type gamma is primarily a secretory protein due to lack of an efficient signal for glycosylphosphatidylinositol modification: protein characterization and cell type specificity. Shen, F., Wu, M., Ross, J.F., Miller, D., Ratnam, M. Biochemistry (1995)
- Relation between trinucleotide GAA repeat length and sensory neuropathy in Friedreich's ataxia. Santoro, L., De Michele, G., Perretti, A., Crisci, C., Cocozza, S., Cavalcanti, F., Ragno, M., Monticelli, A., Filla, A., Caruso, G. J. Neurol. Neurosurg. Psychiatr. (1999)
- Glycogen storage in multiple muscles of old GSD-II mice can be rapidly cleared after a single intravenous injection with a modified adenoviral vector expressing hGAA. Xu, F., Ding, E., Migone, F., Serra, D., Schneider, A., Chen, Y.T., Amalfitano, A. The journal of gene medicine. (2005)
- Extension of human acid alpha-glucosidase polymorphism by isoelectric focusing in polyacrylamide gel. Nickel, B.E., McAlpine, P.J. Ann. Hum. Genet. (1982)