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MeSH Review

Shwartzman Phenomenon

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Disease relevance of Shwartzman Phenomenon


High impact information on Shwartzman Phenomenon


Chemical compound and disease context of Shwartzman Phenomenon


Biological context of Shwartzman Phenomenon


Anatomical context of Shwartzman Phenomenon


Gene context of Shwartzman Phenomenon


Analytical, diagnostic and therapeutic context of Shwartzman Phenomenon


  1. Neutralization of meningococcal endotoxin by antibody to core glycolipid. Davis, C.E., Ziegler, E.J., Arnold, K.F. J. Exp. Med. (1978) [Pubmed]
  2. Resistance of natural killer T cell-deficient mice to systemic Shwartzman reaction. Dieli, F., Sireci, G., Russo, D., Taniguchi, M., Ivanyi, J., Fernandez, C., Troye-Blomberg, M., De Leo, G., Salerno, A. J. Exp. Med. (2000) [Pubmed]
  3. Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance. Berg, D.J., Kühn, R., Rajewsky, K., Müller, W., Menon, S., Davidson, N., Grünig, G., Rennick, D. J. Clin. Invest. (1995) [Pubmed]
  4. Increased release of tumor necrosis factor-alpha into the cerebrospinal fluid and peripheral circulation of aged rats. Sirén, A.L., Liu, Y., Feuerstein, G., Hallenbeck, J.M. Stroke (1993) [Pubmed]
  5. Low endotoxic activities of synthetic Salmonella-type lipid A with an additional acyloxyacyl group on the 2-amino group of beta (1-6) glucosamine disaccharide 1,4'-bisphosphate. Kotani, S., Takada, H., Takahashi, I., Tsujimoto, M., Ogawa, T., Ikeda, T., Harada, K., Okamura, H., Tamura, T., Tanaka, S. Infect. Immun. (1986) [Pubmed]
  6. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. Saeed, R.W., Varma, S., Peng-Nemeroff, T., Sherry, B., Balakhaneh, D., Huston, J., Tracey, K.J., Al-Abed, Y., Metz, C.N. J. Exp. Med. (2005) [Pubmed]
  7. Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction. Ozmen, L., Pericin, M., Hakimi, J., Chizzonite, R.A., Wysocka, M., Trinchieri, G., Gately, M., Garotta, G. J. Exp. Med. (1994) [Pubmed]
  8. A study of the large heparin requirements in the generalized Shwartzman reaction. Gurewich, V., Lipinski, B., Wetmore, R. Blood (1976) [Pubmed]
  9. Cutting edge: IL-15 costimulates the generalized Shwartzman reaction and innate immune IFN-gamma production in vivo. Fehniger, T.A., Yu, H., Cooper, M.A., Suzuki, K., Shah, M.H., Caligiuri, M.A. J. Immunol. (2000) [Pubmed]
  10. The effects of indomethacin on the generalized shwartzman reaction. Howes, E.L., Kwok, M.T., McKay, D.G. Am. J. Pathol. (1978) [Pubmed]
  11. Cutaneous vascular fibrinolytic activity in the local Shwartzman reaction. Bergstein, J.M. Am. J. Pathol. (1977) [Pubmed]
  12. Effect of cyclosporin on generalized Shwartzman reaction in diabetic rats. Bunchman, T.E., Mauer, S.M., Kim, Y. Diabetes (1990) [Pubmed]
  13. Sensitization to the generalized Shwartzman reaction by catechol-O-methyltransferase inhibitors. Latour, J.G., Láger-Gauthier, C. Am. J. Pathol. (1978) [Pubmed]
  14. Effects of thalidomide on the local Shwartzman reaction in mice and rabbits. Geist, C., Wöhrmann, T., Schneider, J., Zwingenberger, K. FEMS Immunol. Med. Microbiol. (1995) [Pubmed]
  15. Involvement of NK1+ T cells and their IFN-gamma production in the generalized Shwartzman reaction. Ogasawara, K., Takeda, K., Hashimoto, W., Satoh, M., Okuyama, R., Yanai, N., Obinata, M., Kumagai, K., Takada, H., Hiraide, H., Seki, S. J. Immunol. (1998) [Pubmed]
  16. Expression of intercellular adhesion molecule-1 (ICAM-1) on vascular endothelial cells and renal tubular cells in the generalized Shwartzman reaction as an experimental disseminated intravascular coagulation model. Koide, N., Abe, K., Narita, K., Kato, Y., Sugiyama, T., Yoshida, T., Yokochi, T. FEMS Immunol. Med. Microbiol. (1997) [Pubmed]
  17. Differentiation of the anti-shock effect of ulinastatin from steroid hormone, by the continuous observation of microcirculation dynamics. Nakajima, K., Goto, Y. Circ. Shock (1992) [Pubmed]
  18. Cytokines and the immune response. Van der Meide, P.H., Schellekens, H. Biotherapy (Dordrecht, Netherlands) (1996) [Pubmed]
  19. Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury. Movat, H.Z., Burrowes, C.E., Cybulsky, M.I., Dinarello, C.A. Am. J. Pathol. (1987) [Pubmed]
  20. Tissue plasminogen activator therapy of glomerular thrombi in the Shwartzman reaction. Bergstein, J.M. Kidney Int. (1989) [Pubmed]
  21. Immunomodulation of LPS ability to induce the local Shwartzman reaction. Aguillón, J.C., Ferreira, V., Núñez, E., Paredes, L., Molina, M.C., Colombo, A., Hermosilla, T., Ferreira, A. Scand. J. Immunol. (1996) [Pubmed]
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