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MeSH Review

Learning Disorders

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Disease relevance of Learning Disorders


Psychiatry related information on Learning Disorders


High impact information on Learning Disorders


Chemical compound and disease context of Learning Disorders


Biological context of Learning Disorders


Anatomical context of Learning Disorders


Gene context of Learning Disorders


Analytical, diagnostic and therapeutic context of Learning Disorders


  1. MYCN haploinsufficiency is associated with reduced brain size and intestinal atresias in Feingold syndrome. van Bokhoven, H., Celli, J., van Reeuwijk, J., Rinne, T., Glaudemans, B., van Beusekom, E., Rieu, P., Newbury-Ecob, R.A., Chiang, C., Brunner, H.G. Nat. Genet. (2005) [Pubmed]
  2. Interleukin 3 prevents delayed neuronal death in the hippocampal CA1 field. Wen, T.C., Tanaka, J., Peng, H., Desaki, J., Matsuda, S., Maeda, N., Fujita, H., Sato, K., Sakanaka, M. J. Exp. Med. (1998) [Pubmed]
  3. NF1 microdeletion syndrome: refined FISH characterization of sporadic and familial deletions with locus-specific probes. Riva, P., Corrado, L., Natacci, F., Castorina, P., Wu, B.L., Schneider, G.H., Clementi, M., Tenconi, R., Korf, B.R., Larizza, L. Am. J. Hum. Genet. (2000) [Pubmed]
  4. Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly. Mykytyn, K., Mullins, R.F., Andrews, M., Chiang, A.P., Swiderski, R.E., Yang, B., Braun, T., Casavant, T., Stone, E.M., Sheffield, V.C. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  5. Velocardiofacial syndrome: learning difficulties and intervention. Kok, L.L., Solman, R.T. J. Med. Genet. (1995) [Pubmed]
  6. Tourette syndrome and other tic disorders. Diagnosis, pathophysiology, and treatment. Singer, H.S., Walkup, J.T. Medicine (Baltimore) (1991) [Pubmed]
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  11. Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nf1. Costa, R.M., Yang, T., Huynh, D.P., Pulst, S.M., Viskochil, D.H., Silva, A.J., Brannan, C.I. Nat. Genet. (2001) [Pubmed]
  12. The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes. Daston, M.M., Scrable, H., Nordlund, M., Sturbaum, A.K., Nissen, L.M., Ratner, N. Neuron (1992) [Pubmed]
  13. Focal cerebral dysfunction in developmental learning disabilities. Lou, H.C., Henriksen, L., Bruhn, P. Lancet (1990) [Pubmed]
  14. Brain anatomy in adults with velocardiofacial syndrome with and without schizophrenia: preliminary results of a structural magnetic resonance imaging study. van Amelsvoort, T., Daly, E., Henry, J., Robertson, D., Ng, V., Owen, M., Murphy, K.C., Murphy, D.G. Arch. Gen. Psychiatry (2004) [Pubmed]
  15. FRAXA and FRAXE: evidence against segregation distortion and for an effect of intermediate alleles on learning disability. Teague, J.W., Morton, N.E., Dennis, N.R., Curtis, G., McKechnie, N., Macpherson, J.N., Murray, A., Pound, M.C., Sharrock, A.J., Youings, S.A., Jacobs, P.A. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  16. A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability. Plomin, R., Turic, D.M., Hill, L., Turic, D.E., Stephens, M., Williams, J., Owen, M.J., O'Donovan, M.C. Mol. Psychiatry (2004) [Pubmed]
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  18. Developmental deficits in adult patients with arteriovenous malformations. Lazar, R.M., Connaire, K., Marshall, R.S., Pile-Spellman, J., Hacein-Bey, L., Solomon, R.A., Sisti, M.B., Young, W.L., Mohr, J.P. Arch. Neurol. (1999) [Pubmed]
  19. Prenatal monosodium glutamate causes long-lasting cholinergic and adrenergic changes in various brain regions. Frieder, B., Grimm, V.E. J. Neurochem. (1987) [Pubmed]
  20. Reliability of DISCUS rating in individuals with learning disabilities. Collacott, R., Bhaumik, S., Branford, D. The British journal of psychiatry : the journal of mental science. (1992) [Pubmed]
  21. Deletions spanning the neurofibromatosis 1 gene: identification and phenotype of five patients. Kayes, L.M., Burke, W., Riccardi, V.M., Bennett, R., Ehrlich, P., Rubenstein, A., Stephens, K. Am. J. Hum. Genet. (1994) [Pubmed]
  22. Cognitive impairment in neurofibromatosis type 1. Ozonoff, S. Am. J. Med. Genet. (1999) [Pubmed]
  23. Permanent motor activity and learning disorders induced by exposure to phenytoin during gestation and early infancy in the rat. Wolansky, M.J., Azcurra, J.M. Neurotoxicology and teratology. (2005) [Pubmed]
  24. Molecular and cellular mechanisms underlying the cognitive deficits associated with neurofibromatosis 1. Costa, R.M., Silva, A.J. J. Child Neurol. (2002) [Pubmed]
  25. Ring chromosome 20 syndrome with intractable epilepsy. Alpman, A., Serdaroglu, G., Cogulu, O., Tekgul, H., Gokben, S., Ozkinay, F. Developmental medicine and child neurology. (2005) [Pubmed]
  26. Outcome in children with fetal mild ventriculomegaly: a case series. Gilmore, J.H., van Tol, J.J., Lewis Streicher, H., Williamson, K., Cohen, S.B., Greenwood, R.S., Charles, H.C., Kliewer, M.A., Whitt, J.K., Silva, S.G., Hertzberg, B.S., Chescheir, N.C. Schizophr. Res. (2001) [Pubmed]
  27. Protective effect of basic fibroblast growth factor-heparin and neurotoxic effect of platelet factor 4 on ischemic neuronal loss and learning disability in gerbils. Wen, T.C., Matsuda, S., Yoshimura, H., Aburaya, J., Kushihata, F., Sakanaka, M. Neuroscience (1995) [Pubmed]
  28. Lateralization of temporal lobe epilepsy and learning disabilities, as defined by disability-related civil rights law. Butterbaugh, G., Olejniczak, P., Roques, B., Costa, R., Rose, M., Fisch, B., Carey, M., Thomson, J., Skinner, J. Epilepsia (2004) [Pubmed]
  29. MODED: microcephaly-oculo-digito-esophageal-duodenal syndrome. Frydman, M., Katz, M., Cabot, S.G., Soen, G., Kauschansky, A., Sirota, L. Am. J. Med. Genet. (1997) [Pubmed]
  30. Altered expression of polysialylated NCAM in mouse hippocampus following trimethyltin administration. Dey, P.M., Polunas, M.A., Philbert, M.A., Reuhl, K.R. Neurotoxicology (1997) [Pubmed]
  31. A mouse model for the learning and memory deficits associated with neurofibromatosis type I. Silva, A.J., Frankland, P.W., Marowitz, Z., Friedman, E., Laszlo, G.S., Cioffi, D., Jacks, T., Bourtchuladze, R., Lazlo, G. Nat. Genet. (1997) [Pubmed]
  32. Mkks-null mice have a phenotype resembling Bardet-Biedl syndrome. Fath, M.A., Mullins, R.F., Searby, C., Nishimura, D.Y., Wei, J., Rahmouni, K., Davis, R.E., Tayeh, M.K., Andrews, M., Yang, B., Sigmund, C.D., Stone, E.M., Sheffield, V.C. Hum. Mol. Genet. (2005) [Pubmed]
  33. Mutations in the TSC1 gene account for a minority of patients with tuberous sclerosis. Ali, J.B., Sepp, T., Ward, S., Green, A.J., Yates, J.R. J. Med. Genet. (1998) [Pubmed]
  34. Decreased calcium/calmodulin-dependent protein kinase II and protein kinase C activities mediate impairment of hippocampal long-term potentiation in the olfactory bulbectomized mice. Moriguchi, S., Han, F., Nakagawasai, O., Tadano, T., Fukunaga, K. J. Neurochem. (2006) [Pubmed]
  35. Characterization and mutation analysis of goosecoid-like (GSCL), a homeodomain-containing gene that maps to the critical region for VCFS/DGS on 22q11. Funke, B., Saint-Jore, B., Puech, A., Sirotkin, H., Edelmann, L., Carlson, C., Raft, S., Pandita, R.K., Kucherlapati, R., Skoultchi, A., Morrow, B.E. Genomics (1997) [Pubmed]
  36. Effect of epilepsy on psychomotor function in children with uncomplicated epilepsy. Boelen, S., Nieuwenhuis, S., Steenbeek, L., Veldwijk, H., van de Ven-Verest, M., Tan, I.Y., Aldenkamp, A.P. Developmental medicine and child neurology. (2005) [Pubmed]
  37. Learning in year-old female autoimmune BXSB mice. Boehm, G.W., Sherman, G.F., Hoplight, B.J., Hyde, L.A., Bradway, D.M., Galaburda, A.M., Ahmed, S.A., Denenberg, V.H. Physiol. Behav. (1998) [Pubmed]
  38. Role of attention deficit hyperactivity disorder in learning disabilities. Golden, G.S. Seminars in neurology. (1991) [Pubmed]
  39. Thalamocortical development of parvalbumin neurons in normal and periventricular leukomalacia brains. Iai, M., Takashima, S. Neuropediatrics. (1999) [Pubmed]
  40. Racial and ethnic differences in ADHD and LD in young school-age children: parental reports in the National Health Interview Survey. Pastor, P.N., Reuben, C.A. Public health reports (Washington, D.C. : 1974) (2005) [Pubmed]
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