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Disease relevance of Insectivora


High impact information on Insectivora

  • The evolution of the thyroid hormone distributor protein transthyretin in the order insectivora, class mammalia [2].
  • The purpose of this study was to characterize the position of Insectivora in the evolution of transthyretin in eutherians, a subclass of Mammalia. Transthyretin was identified by thyroxine binding and Western analysis in the blood of adult shrews, hedgehogs, and moles [2].
  • Also, the pattern of transthyretin precursor mRNA splicing in Insectivora was more similar to that in other eutherians than to that in marsupials, reptiles, and birds [2].
  • Pregnancy maintenance and progesterone concentrations in the musk shrew, Suncus murinus (order: Insectivora) [3].
  • In isolated preparations of the urinary bladder detrusor of the house musk shrew Suncus murinus (order: insectivora; family: Soricidae), electrical field stimulation (0.5-32 pulses/s) evoked neurogenic contractile responses that were markedly attenuated by atropine (1 microM) [4].

Biological context of Insectivora


Anatomical context of Insectivora

  • The distribution, morphological features, and postnatal development of parvalbumin (PV) immunoreactive neurons in the main olfactory bulb (MOB) of the house musk shrew, Suncus murinus, were studied to report for the first time on PV positive bulbar interneurons in the order Insectivora [7].
  • Cyto- and myeloarchitectonics as well as acetylcholinesterase activity of the nucleus limitans thalami--an important part of the nociceptive system--were studied in insectivora (Sorex araneus, Erinaceus europaeus, Talpa europaeus), rat, rabbit, cat, monkey and man [8].

Associations of Insectivora with chemical compounds


Gene context of Insectivora


  1. Diabetic cataract of the musk shrew (Suncus murinus, Insectivora) exhibiting spontaneous non-insulin dependent diabetes mellitus (NIDDM). Ohno, T., Kitoh, J., Tanaka, S., Nishimura, M., Namikawa, T. Exp. Anim. (2001) [Pubmed]
  2. The evolution of the thyroid hormone distributor protein transthyretin in the order insectivora, class mammalia. Prapunpoj, P., Richardson, S.J., Fumagalli, L., Schreiber, G. Mol. Biol. Evol. (2000) [Pubmed]
  3. Pregnancy maintenance and progesterone concentrations in the musk shrew, Suncus murinus (order: Insectivora). Hasler, M.J., Nalbandov, A.V. Biol. Reprod. (1978) [Pubmed]
  4. Neuromuscular transmission and innervation in the urinary bladder of the insectivore Suncus murinus. Hoyle, C.H., Chakrabarti, G., Pendleton, N.P., Andrews, P.L. J. Auton. Nerv. Syst. (1998) [Pubmed]
  5. Morphogenesis of esophageal carcinoma induced by N-methyl-N'-nitro-N-nitrosoguanidine in the house musk shrew, Suncus murinus (Insectivora). Fujita, Y., Oyaizu, T., Takahashi, H., Oishi, Y., Tsubura, A. Jpn. J. Cancer Res. (1994) [Pubmed]
  6. Unique regulation of thyroid hormone metabolism during fasting in the house musk shrew (Suncus murinus, Insectivora: Soricidae). Takeuchi, Y., Suzuki, D., Oda, S., Refetoff, S., Seki, K., Tsunekawa, K., Kasahara, T., Murakami, M., Murata, Y. Gen. Comp. Endocrinol. (2006) [Pubmed]
  7. Parvalbumin immunoreactive neurons in the main olfactory bulb of the house musk shrew, Suncus murinus. Kakuta, S., Oda, S., Takayanagi, M., Kishi, K. Brain Behav. Evol. (1998) [Pubmed]
  8. Nucleus limitans thalami--comparative anatomical study. Moryś, J., Dziewiatkowski, J., Bobiński, M., Narkiewicz, O. Acta neurobiologiae experimentalis. (1989) [Pubmed]
  9. Esophageal carcinoma in house musk shrews, Suncus murinus (Insectivora), induced by N-methyl-N'-nitro-N-nitrosoguanidine. Tsubura, A., Senzaki, H., Takahashi, H., Oyaizu, T., Morii, S. J. Cancer Res. Clin. Oncol. (1993) [Pubmed]
  10. Toxin-induced IDDM (insulin dependent diabetes mellitus) in the musk shrew. Ohno, T., Kitoh, J., Yamashita, K., Ichikawa, Y., Horio, F., Terada, M., Tanaka, S., Namikawa, T. Life Sci. (1998) [Pubmed]
  11. Liver apoptosis after dimethylnitrosamine administration in shrews. Shikata, N., Oyaizu, T., Senzaki, H., Uemura, Y., Tsubura, A. Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie. (1996) [Pubmed]
  12. Record of Psilotornus confertus Machalska, 1974 (Trematoda: Psilostomidae), a parasite of birds, in water-shrew Neomys fodiens Pennant, 1771 (Insectivora: Soricidae) in the Oriental Pyrenean Mountains. Mas-coma, S. Folia Parasitol. (1978) [Pubmed]
  13. Fungi from interior organs of free-living small mammals in Czechoslovakia and Yugoslavia. Hubálek, Z., Rosický, B., Otcenásek, M. Folia Parasitol. (1980) [Pubmed]
  14. Neuropeptide Y-like immunoreactive neurons in the suprachiasmatic-subparaventricular region in the hedgehog-tenrec. Künzle, H., Unger, J.W. Brain Res. (1992) [Pubmed]
  15. Robertsonian metacentrics of the house musk shrew (Suncus murinus, Insectivora, Soricidae) lose the telomeric sequences in the centromeric area. Rogatcheva, M.B., Ono, T., Sonta, S., Oda, S., Borodin, P.M. Genes Genet. Syst. (2000) [Pubmed]
  16. Organ distribution, purification and characterization of kynureninase in Suncus murinus (Insectivora) and anthranilic acid level in the serum. Ishikawa, T., Okuno, E., Kawai, J., Kido, R. Comp. Biochem. Physiol., B (1989) [Pubmed]
  17. Genetic differentiation between laboratory lines of the musk shrew (Suncus murinus, Insectivora) based on restriction endonuclease cleavage patterns of mitochondrial DNA. Yamagata, T., Ishikawa, A., Tsubota, Y., Namikawa, T., Hirai, A. Biochem. Genet. (1987) [Pubmed]
  18. Phylogenetic positions of insectivora in eutheria inferred from mitochondrial cytochrome c oxidase subunit II gene. Onuma, M., Kusakabe, T., Kusakabe, S. Zool. Sci. (1998) [Pubmed]
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