High impact information on Lingual Nerve

• By E14, lingual nerve afferents first enter the tongue in vivo, and the repellant influence becomes restricted to the midline [1].
• The central cut end of the lingual nerve (LN) was stimulated electrically to simulate somatic stimulation, and 1 microL of lidocaine (2%) was microinjected into the Vsp or the EW nucleus to determine its effect on the pupillary dilation induced by LN stimulation [2].
• The effect of triamcinolone hexacetonide on the spontaneous and mechanically-induced ectopic discharge following lingual nerve injury in the ferret [3].
• P2X purinoceptor-mediated excitation of trigeminal lingual nerve terminals in an in vitro intra-arterially perfused rat tongue preparation [4].
• We conclude that the application of BDNF to a site of lingual nerve repair has a negative effect on the long-term outcome [5].

Biological context of Lingual Nerve

• We measured the effects of electrical stimulation of the central cut end of the lingual nerve on lower lip blood flow (LBF) and on arterial blood pressure in urethane-anesthetized, artificially ventilated, cervically vagosympathectomized rabbits [6].
• Parasympathetic reflex vasodilation was elicited in the lower lip by stimulation of the central cut end of the lingual nerve in urethane plus alpha-chloralose-anesthetized, vago-sympathectomized cats [7].

Anatomical context of Lingual Nerve

• Neural cell adhesion molecule, neuron-specific enolase and calcitonin gene-related peptide immunoreactivity in hamster taste buds after chorda tympani/lingual nerve denervation [8].
• Using tungsten microelectrodes, we have recorded from 28 afferents in the inferior alveolar nerve and 21 afferents in the lingual nerve of human volunteers [9].
• CONCLUSION: Damage to the lingual nerve results in marked changes to axon diameter, myelin sheath thickness, and Schwann cell-axon relationships [10].
• Lanthanum chloride, which inhibited lingual nerve responses to hydrophilic compounds, presumably by blocking their diffusion across tight junctions, did not inhibit responses to these non-electrolytes [11].
• Lingual split technique. Damage to inferior alveolar and lingual nerves during removal of impacted mandibular third molars [12].

Associations of Lingual Nerve with chemical compounds

• Intrafascicular multiunit activity and impulses in single mechanoreceptive afferents were recorded from the human lingual nerve with permucosally inserted tungsten microelectrodes [13].
• The results suggest that inhibition of hypoglossal motoneurons via the lingual nerve is more likely to be mediated by glycine than gamma-aminobutyric acid (GABA) and is therefore similar to the strychnine-sensitive postsynaptic inhibition of spinal motoneurons [14].
• Tongue adaptation temperature influences lingual nerve responses to thermal and menthol stimulation [15].
• Fourteen volunteers participated (21-30 years) in two randomized sessions; before, during a nerve block of the lingual nerve or topical capsaicin application (30 mul 5%) on the tongue, and after anesthesia or pain had subsided [16].
• Using both single and multiunit recordings of trigeminal neurons in the lingual nerve of rat, we measured responses to cool (24 degrees C), noxiously hot (55 degrees C) and cold (8 degrees C) H2O, NH4Cl and supersaturated solutions of CO2 (24 degrees C and 33 degrees C) [17].

Gene context of Lingual Nerve

• These results suggest that TRPM8 protein is present in sensory lingual nerve fibers mainly projected from TG and might work as cold and l-menthol receptors on tongue [18].
• The superficial sensory function of the inferior alveolar and the lingual nerve was assessed with the Pointed-Blunt Test, the Two-Point-Discrimination Test and the objective method of the 'Pain and Thermal Sensitivity' Test (PATH Test) [19].
• An electrophysiological study into the effect of neurotrophin-3 on functional recovery after lingual nerve repair [20].
• (3) Fungiform papillae may be transformed filiform papillae induced and maintained by a neurotrophic factor of factors coming from the chorda tympani and/or lingual nerve [21].

Analytical, diagnostic and therapeutic context of Lingual Nerve

• This minor effect of the antagonists on the carbachol-induced depression of XII nerve activity was in contrast to the marked disinhibitory effects that both antagonists had on the XII nerve response to electrical stimulation of the lingual nerve [22].
• To test the effect of local anesthesia (LA) of the lingual nerve and topical application of capsaicin stimulation on tongue MEPs [16].

References