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MeSH Review


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Disease relevance of Diskectomy


High impact information on Diskectomy

  • CONCLUSION: Minor disk degeneration but not herniation volume represents a risk factor for the recurrence of disk herniation after diskectomy [6].
  • MATERIALS AND METHODS: Three neuroradiologists retrospectively evaluated sagittal T2-weighted conventional spin-echo and FSE images obtained in 15 patients with metallic artifacts from various sources including drill particles from anterior cervical diskectomy, posterior fixation wires, fixation rods or plates, and an inferior vena cava filter [7].
  • In both cases, anterior cervical discectomy at one or two levels was undertaken with bone graft and titanium implants, and cortical SEP were monitored to alternate stimulation of the left and right median or ulnar nerves [8].
  • The procedure of choice for soft disc herniation, MRI on a 0.5 T superconducting system associated with plain radiography of the cervical spine, in selecting patients for anterior cervical discectomy without interbody fusion (ACD), was evaluated [9].
  • Epidural steroid injection compared with discectomy for the treatment of lumbar disc herniation [10].

Chemical compound and disease context of Diskectomy


Anatomical context of Diskectomy

  • A prospective clinical trial was conducted involving patients with prolapsed lumbar intervertebral disk proven myelographically, who had anterior diskectomy and disk replacement with a titanium-mesh block implant [16].
  • Morphometric evaluation of 54 dry cervical spines from C3 to C7 (a total of 270 cervical vertebrae) was performed to determine the bony boundaries of the uncinate process for resection of the uncinate process for access to posterolateral osteophytes or herniated disks at the time of anterior cervical diskectomy [17].

Associations of Diskectomy with chemical compounds

  • One hundred patients who had no improvement after a minimum of six weeks of noninvasive treatment were enrolled in a prospective, non-blinded study and were randomly assigned to receive either epidural steroid injection or discectomy [18].
  • Anterior cervical discectomy with hydroxylapatite fusion [19].
  • The authors have compared the radiological and histological effects of performing anterior cervical discectomy with the CO2 laser to those of performing it by standard operative technique [20].
  • In order to evaluate the performance of feedback fuzzy logic control of inspired oxygen and isoflurane concentrations, we studied 30 patients undergoing discectomy for lumbar (n = 26) or cervical (n = 4) disc herniation [21].
  • INTERVENTION: An anterior cervical discectomy at C6/C7 and fusion with autologous bone graft were performed [22].

Gene context of Diskectomy

  • However, incidence of a fracture-dislocation through a solid multilevel anterior cervical discectomy and fusion (ACDF) construct with no associated underlying pathology of AS, DISH, or OPLL but severe osteopenia has not, to the best knowledge of the authors, been reported in the medical literature [23].
  • A prospective randomized study to compare discectomy without (DE) and with fusion (DEF) included 63 patients operated on with DE returned to work during the first 9 weeks postoperatively than patients operated on with DEF (p less than 0.005 to 0.05) [24].
  • Patients suffering from persisting sciatic pain 8 weeks following discectomy were compared with patients displaying low complaints and healthy, pain-free volunteers regarding their interleukin-6 (IL-6) levels, morning cortisol levels and degree of psychological distress [25].
  • Anterior BAK instrumentation and fusion: complete versus partial discectomy [26].
  • The objective of this study was the detection of IL-1beta and IL-1Ra secreted by herniated lumbar discal cells after discectomy [27].

Analytical, diagnostic and therapeutic context of Diskectomy


  1. Anterior cervical vertebrectomy and interbody fusion for multi-level spondylosis and ossification of the posterior longitudinal ligament. Kojima, T., Waga, S., Kubo, Y., Kanamaru, K., Shimosaka, S., Shimizu, T. Neurosurgery (1989) [Pubmed]
  2. Dural arteriovenous fistula and progressive conus medullaris syndrome as complications of lumbar discectomy. Case report. Asakuno, K., Kim, P., Kawamoto, T., Ogino, M. J. Neurosurg. (2002) [Pubmed]
  3. Ventral discectomy with pmma interbody fusion for cervical disc disease: long-term results in 249 patients. Hamburger, C., Festenberg, F.V., Uhl, E. Spine. (2001) [Pubmed]
  4. Defining the use of gadolinium enhanced MRI in the assessment of the postoperative lumbar spine. Wilkinson, L.S., Elson, E., Saifuddin, A., Ransford, A.O. Clinical radiology. (1997) [Pubmed]
  5. Clinical long-term results of anterior discectomy without interbody fusion for cervical disc disease. Yamamoto, I., Ikeda, A., Shibuya, N., Tsugane, R., Sato, O. Spine. (1991) [Pubmed]
  6. Lumbar disk herniation: do MR imaging findings predict recurrence after surgical diskectomy? Dora, C., Schmid, M.R., Elfering, A., Zanetti, M., Hodler, J., Boos, N. Radiology. (2005) [Pubmed]
  7. Metallic artifacts on MR images of the postoperative spine: reduction with fast spin-echo techniques. Tartaglino, L.M., Flanders, A.E., Vinitski, S., Friedman, D.P. Radiology. (1994) [Pubmed]
  8. Two cases of quadriparesis following anterior cervical discectomy, with normal perioperative somatosensory evoked potentials. Jones, S.J., Buonamassa, S., Crockard, H.A. J. Neurol. Neurosurg. Psychiatr. (2003) [Pubmed]
  9. Diagnostic imaging algorithm for cervical soft disc herniation. Van de Kelft, E., van Vyve, M. J. Neurol. Neurosurg. Psychiatr. (1994) [Pubmed]
  10. Epidural steroid injection compared with discectomy for the treatment of lumbar disc herniation. McLain, R.F. The Journal of bone and joint surgery. American volume. (2005) [Pubmed]
  11. Subsidence of stand-alone cervical cages in anterior interbody fusion: warning. Gercek, E., Arlet, V., Delisle, J., Marchesi, D. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. (2003) [Pubmed]
  12. Recurrent acute upper airway obstruction after anterior cervical fusion. Penberthy, A., Roberts, N. Anaesthesia and intensive care. (1998) [Pubmed]
  13. Perioperative use of corticosteroid and bupivacaine combination in lumbar disc surgery: a randomized controlled trial. Mirzai, H., Tekin, I., Alincak, H. Spine. (2002) [Pubmed]
  14. Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study. Pandey, C.K., Navkar, D.V., Giri, P.J., Raza, M., Behari, S., Singh, R.B., Singh, U., Singh, P.K. Journal of neurosurgical anesthesiology. (2005) [Pubmed]
  15. Role of peridural fibrosis in the failed back: a review. Robertson, J.T. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. (1996) [Pubmed]
  16. Titanium-mesh block replacement of the intervertebral disk. Leong, J.C., Chow, S.P., Yau, A.C. Clin. Orthop. Relat. Res. (1994) [Pubmed]
  17. Cervical uncinate process: an anatomic study for anterior decompression of the cervical spine. Lu, J., Ebraheim, N.A., Yang, H., Skie, M., Yeasting, R.A. Surgical and radiologic anatomy : SRA. (1998) [Pubmed]
  18. Treatment of lumbar disc herniation: epidural steroid injection compared with discectomy. A prospective, randomized study. Buttermann, G.R. The Journal of bone and joint surgery. American volume. (2004) [Pubmed]
  19. Anterior cervical discectomy with hydroxylapatite fusion. Senter, H.J., Kortyna, R., Kemp, W.R. Neurosurgery (1989) [Pubmed]
  20. Comparative histological and radiographic effects of CO2 laser versus standard surgical anterior cervical discectomy in the dog. Gropper, G.R., Robertson, J.H., McClellan, G. Neurosurgery (1984) [Pubmed]
  21. Fuzzy logic control of inspired isoflurane and oxygen concentrations using minimal flow anaesthesia. Curatolo, M., Derighetti, M., Petersen-Felix, S., Feigenwinter, P., Fischer, M., Zbinden, A.M. British journal of anaesthesia. (1996) [Pubmed]
  22. Cervical spinal cord compression attributable to a calcified intervertebral disc in a patient with X-linked hypophosphatemic rickets: case report and review of the literature. Soehle, M., Casey, A.T. Neurosurgery (2002) [Pubmed]
  23. Traumatic fracture-dislocation of C5 on C6 through a previously solid multilevel anterior cervical discectomy and fusion: a case report and review of the literature. Orndorff, D.G., Samartzis, D., Whitehill, R., Shen, F.H. The spine journal : official journal of the North American Spine Society. (2006) [Pubmed]
  24. Anterior cervical discectomy with and without fusion. A prospective study. Rosenørn, J., Hansen, E.B., Rosenørn, M.A. J. Neurosurg. (1983) [Pubmed]
  25. Psychoneuroimmunological correlates of persisting sciatic pain in patients who underwent discectomy. Geiss, A., Varadi, E., Steinbach, K., Bauer, H.W., Anton, F. Neurosci. Lett. (1997) [Pubmed]
  26. Anterior BAK instrumentation and fusion: complete versus partial discectomy. McAfee, P.C., Lee, G.A., Fedder, I.L., Cunningham, B.W. Clin. Orthop. Relat. Res. (2002) [Pubmed]
  27. Spontaneous secretion of interleukin 1 receptor antagonist (IL-1ra) by cells isolated from herniated lumbar discal tissue after discectomy. Koch, H., Reinecke, J.A., Meijer, H., Wehling, P. Cytokine (1998) [Pubmed]
  28. Dexamethasone--a helpful adjunct in management after lumbar discectomy. King, J.S. Neurosurgery (1984) [Pubmed]
  29. The surgical management of ossification of the posterior longitudinal ligament in 43 north americans. Epstein, N.E. Spine. (1994) [Pubmed]
  30. Microlumbar discectomy. Is it safe as an outpatient procedure? Zahrawi, F. Spine. (1994) [Pubmed]
  31. Resorbable polylactic acid interbody spacers with vertebral autograft for anterior cervical discectomy and fusion. Wang, M.Y., Liu, C.Y. Neurosurgery (2005) [Pubmed]
  32. Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions, patient outcomes and comparison to fusion with allograft. Moreland, D.B., Asch, H.L., Clabeaux, D.E., Castiglia, G.J., Czajka, G.A., Lewis, P.J., Egnatchik, J.G., Cappuccino, A., Huynh, L. The spine journal : official journal of the North American Spine Society. (2004) [Pubmed]
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