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MeSH Review

Anesthesia, General

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Disease relevance of Anesthesia, General


Psychiatry related information on Anesthesia, General


High impact information on Anesthesia, General

  • At the human median effect dose (ED50) for general anesthesia, the (+)-isomer was about twofold more effective than the (-)-isomer both in eliciting the anesthetic-activated potassium current IK(An) and in inhibiting a current mediated by neuronal nicotinic acetylcholine receptors [9].
  • This finding has implications for PCP abuse and also for the use of its derivative in general anesthesia, where it may contribute to postoperative infection [10].
  • We conclude that the risk of general anesthesia and major noncardiac surgery is low in patients with hypertrophic obstructive cardiomyopathy [11].
  • Eighteen patients undergoing coronary artery surgery were observed to examine whether cocaine in a clinically used dose exerts sympathomimetic effects during general anesthesia [12].
  • Is cocaine a sympathetic stimulant during general anesthesia [12]?

Chemical compound and disease context of Anesthesia, General


Biological context of Anesthesia, General


Anatomical context of Anesthesia, General


Associations of Anesthesia, General with chemical compounds


Gene context of Anesthesia, General


Analytical, diagnostic and therapeutic context of Anesthesia, General


  1. Harvesting bone marrow in an outpatient setting using newer anesthetic agents. Thorne, A.C., Stewart, M., Gulati, S.C. J. Clin. Oncol. (1993) [Pubmed]
  2. A cluster of anaphylactic reactions in children with spina bifida during general anesthesia: epidemiologic features, risk factors, and latex hypersensitivity. Kelly, K.J., Pearson, M.L., Kurup, V.P., Havens, P.L., Byrd, R.S., Setlock, M.A., Butler, J.C., Slater, J.E., Grammer, L.C., Resnick, A. J. Allergy Clin. Immunol. (1994) [Pubmed]
  3. Chorioretinal biopsy in dogs. Constable, I.J., Slatter, D.H., Horne, R. Invest. Ophthalmol. Vis. Sci. (1980) [Pubmed]
  4. Effects of ondansetron in the prevention of postoperative nausea and vomiting in children. Ummenhofer, W., Frei, F.J., Urwyler, A., Kern, C., Drewe, J. Anesthesiology (1994) [Pubmed]
  5. Premedication with famotidine augments core hypothermia during general anesthesia. Hirose, M., Hara, Y., Matsusaki, M. Anesthesiology (1995) [Pubmed]
  6. Intravenous nitroglycerin for internal podalic version of the second twin in transverse lie. Dufour, P., Vinatier, D., Vanderstichele, S., Ducloy, A.S., Depret, S., Monnier, J.C. Obstetrics and gynecology. (1998) [Pubmed]
  7. Morphine physical dependence in the hibernator: central nervous system mechanisms underlying the development of dependence remain functional during depression induced by pentobarbital anesthesia. Beckman, A.L., Beaver, T.A., Lewis, F.A. Life Sci. (1993) [Pubmed]
  8. Decrease of isoprene concentrations in blood during general anesthesia. Cailleux, A., Moreau, X., Delhumeau, A., Allain, P. Biochem. Med. Metab. Biol. (1993) [Pubmed]
  9. Stereospecific effects of inhalational general anesthetic optical isomers on nerve ion channels. Franks, N.P., Lieb, W.R. Science (1991) [Pubmed]
  10. Phencyclidine-induced immunodepression. Khansari, N., Whitten, H.D., Fudenberg, H.H. Science (1984) [Pubmed]
  11. Perioperative anesthetic risk of noncardiac surgery in hypertrophic obstructive cardiomyopathy. Thompson, R.C., Liberthson, R.R., Lowenstein, E. JAMA (1985) [Pubmed]
  12. Is cocaine a sympathetic stimulant during general anesthesia? Barash, P.G., Kopriva, C.J., Langou, R., VanDyke, C., Jatlow, P., Stahl, A., Byck, R. JAMA (1980) [Pubmed]
  13. Effects of general anesthesia on anandamide blood levels in humans. Schelling, G., Hauer, D., Azad, S.C., Schmoelz, M., Chouker, A., Schmidt, M., Hornuss, C., Rippberger, M., Briegel, J., Thiel, M., Vogeser, M. Anesthesiology (2006) [Pubmed]
  14. Epidural anesthesia impairs both central and peripheral thermoregulatory control during general anesthesia. Joris, J., Ozaki, M., Sessler, D.I., Hardy, A.F., Lamy, M., McGuire, J., Blanchard, D., Schroeder, M., Moayeri, A. Anesthesiology (1994) [Pubmed]
  15. Pulsus alternans during general anesthesia with halothane: effects of permissive hypercapnia. Saghaei, M., Mortazavian, M. Anesthesiology (2000) [Pubmed]
  16. A comparison between bupivacaine instillation versus ilioinguinal/iliohypogastric nerve block for postoperative analgesia following inguinal herniorrhaphy in children. Casey, W.F., Rice, L.J., Hannallah, R.S., Broadman, L., Norden, J.M., Guzzetta, P. Anesthesiology (1990) [Pubmed]
  17. Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery. Oddby-Muhrbeck, E., Eksborg, S., Bergendahl, H.T., Muhrbeck, O., Lönnqvist, P.A. Anesthesiology (2002) [Pubmed]
  18. Effects of atrial natriuretic peptide on coronary vascular resistance in the intact awake dog. Laxson, D.D., Dai, X.Z., Schwartz, J.S., Bache, R.J. J. Am. Coll. Cardiol. (1988) [Pubmed]
  19. Differential effects of isoflurane on SEP recorded over parietal and frontal scalp. Nogueira, M.C., Brunko, E., Vandesteen, A., De Rood, M., Zegers de Beyl, D. Neurology (1989) [Pubmed]
  20. Anesthetic interaction with ketosteroid isomerase: insights from molecular dynamics simulations. Yonkunas, M.J., Xu, Y., Tang, P. Biophys. J. (2005) [Pubmed]
  21. Intraportal hepatocyte transplantation in the pig: hemodynamic and histopathological study. Muraca, M., Neri, D., Parenti, A., Feltracco, P., Granato, A., Vilei, M.T., Ferraresso, C., Ballarin, R., Zanusso, G.E., Giron, G., Rozga, J., Gerunda, G. Transplantation (2002) [Pubmed]
  22. The Combitube in elective surgery: a report of 200 cases. Gaitini, L.A., Vaida, S.J., Mostafa, S., Yanovski, B., Croitoru, M., Capdevila, M.D., Sabo, E., Ben-David, B., Benumof, J. Anesthesiology (2001) [Pubmed]
  23. CYP2C19 genotype affects diazepam pharmacokinetics and emergence from general anesthesia. Inomata, S., Nagashima, A., Itagaki, F., Homma, M., Nishimura, M., Osaka, Y., Okuyama, K., Tanaka, E., Nakamura, T., Kohda, Y., Naito, S., Miyabe, M., Toyooka, H. Clin. Pharmacol. Ther. (2005) [Pubmed]
  24. Blockade of peripheral neuronal barrage reduces postoperative pain. Gordon, S.M., Dionne, R.A., Brahim, J., Jabir, F., Dubner, R. Pain (1997) [Pubmed]
  25. Increase in the rat blood leukocyte counts induced by PAF-acether is suppressed by general anesthesia. Bozza, P.T., Silva, P.M., Castro-Faria-Neto, H.C., Martins, M.A., Cordeiro, R.S. J. Leukoc. Biol. (1992) [Pubmed]
  26. Cerebrospinal fluid signal intensity increase on FLAIR MR images in patients under general anesthesia: the role of supplemental O2. Deliganis, A.V., Fisher, D.J., Lam, A.M., Maravilla, K.R. Radiology. (2001) [Pubmed]
  27. Relationships among Doppler-derived umbilical artery absolute velocities, cardiac function, and placental volume blood flow and resistance in fetal sheep. Acharya, G., Erkinaro, T., Mäkikallio, K., Lappalainen, T., Rasanen, J. Am. J. Physiol. Heart Circ. Physiol. (2004) [Pubmed]
  28. The effect of sodium taurocholate on biliary iodipamide excretion in the dog. Burgener, F.A., Fischer, H.W. Gastroenterology (1976) [Pubmed]
  29. Isoniazid-rifampin fulminant hepatitis. A possible consequence of the enhancement of isoniazid hepatotoxicity by enzyme induction. Pessayre, D., Bentata, M., Degott, C., Nouel, O., Miguet, J.P., Rueff, B., Benhamou, J.P. Gastroenterology (1977) [Pubmed]
  30. Long-term retention of learning-induced receptive-field plasticity in the auditory cortex. Weinberger, N.M., Javid, R., Lepan, B. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  31. The action of halothane on stimulus-secretion coupling in clonal (GH3) pituitary cells. Stern, R.C., Herrington, J., Lingle, C.J., Evers, A.S. J. Neurosci. (1991) [Pubmed]
  32. Volatile anesthetics activate the human tandem pore domain baseline K+ channel KCNK5. Gray, A.T., Zhao, B.B., Kindler, C.H., Winegar, B.D., Mazurek, M.J., Xu, J., Chavez, R.A., Forsayeth, J.R., Yost, C.S. Anesthesiology (2000) [Pubmed]
  33. Volatile anesthetics and succinylcholine in cardiac ryanodine receptor defects. Swan, H., Laitinen, P.J., Toivonen, L. Anesth. Analg. (2004) [Pubmed]
  34. Relationship between adrenomedullin and vasopressin-aquaporin system under general anesthesia. Ogura, T., Morita, K., Takeuchi, M., Otsuka, F., Iwasaki, T., Oe, K., Matsuura, K., Tobe, K., Mimura, Y., Kishida, M., Makino, H., Hirakawa, M. Horm. Res. (2003) [Pubmed]
  35. Effect of general anesthesia on the abnormal immune response in patients with rheumatoid arthritis. Tanno, M., Nakajima, A., Ishiwata, T., Naito, Z., Yoshino, S. Clinical and experimental rheumatology. (2004) [Pubmed]
  36. Circulation of CD34+ hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factor. Siena, S., Bregni, M., Brando, B., Ravagnani, F., Bonadonna, G., Gianni, A.M. Blood (1989) [Pubmed]
  37. Clinical examination following preoperative chemoradiation for rectal cancer is not a reliable surrogate end point. Guillem, J.G., Chessin, D.B., Shia, J., Moore, H.G., Mazumdar, M., Bernard, B., Paty, P.B., Saltz, L., Minsky, B.D., Weiser, M.R., Temple, L.K., Cohen, A.M., Wong, W.D. J. Clin. Oncol. (2005) [Pubmed]
  38. Postoperative protein sparing with epidural analgesia and hypocaloric dextrose. Schricker, T., Meterissian, S., Wykes, L., Eberhart, L., Lattermann, R., Carli, F. Ann. Surg. (2004) [Pubmed]
  39. Effects of naloxone on prolactin, luteinizing hormone, and cortisol responses to surgical stress in humans. Pontiroli, A.E., Baio, G., Stella, L., Crescenti, A., Girardi, A.M. J. Clin. Endocrinol. Metab. (1982) [Pubmed]
  40. Cephalothin kinetics: before, during, and after cardiopulmonary bypass surgery. Miller, K.W., Chan, K.K., McCoy, H.G., Fischer, R.P., Lindsay, W.G., Zaske, D.E. Clin. Pharmacol. Ther. (1979) [Pubmed]
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