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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Appetite Regulation

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Disease relevance of Appetite Regulation

  • Effect of dehydroepiandrosterone on neurotransmitter levels and appetite regulation of the obese Zucker rat. The Obesity Research Program [1].
  • CONCLUSIONS: An activation of the TNF system, together with reciprocal changes in plasma concentrations of two neuropeptides with opposing appetite regulation, that is increased concentrations of CCK-8s but lower levels of beta-endorphin, are associated with the presence of HIV wasting [2].
  • The observation of NPY gene expression in brain regions involved in appetite regulation is consistent with the recognized importance of NPY in FI regulation in a variety of species, and with the chronic hyperphagia, characteristic of the broiler [3].
  • The understanding of interactions between leptin and insulin and their roles in glucose and body weight regulation provides clues towards mechanisms underlying altered appetite regulation and increased risk of type 2 diabetes in low birth weight individuals [4].

Psychiatry related information on Appetite Regulation

  • Moreover, data from experimental animals show that CRF may influence several processes known to be altered in the overall symptom complex of depression, including not only pituitary-adrenal function, but also motor activity, appetite regulation and sexual behavior [5].

High impact information on Appetite Regulation


Biological context of Appetite Regulation


Associations of Appetite Regulation with chemical compounds


Gene context of Appetite Regulation


Analytical, diagnostic and therapeutic context of Appetite Regulation


  1. Effect of dehydroepiandrosterone on neurotransmitter levels and appetite regulation of the obese Zucker rat. The Obesity Research Program. Abadie, J.M., Wright, B., Correa, G., Browne, E.S., Porter, J.R., Svec, F. Diabetes (1993) [Pubmed]
  2. Altered concentrations of appetite regulators may contribute to the development and maintenance of HIV-associated wasting. Arnalich, F., Martinez, P., Hernanz, A., González, J., Plaza, M.A., Montiel, C., Peña, J.M., Vázquez, J.J. AIDS (1997) [Pubmed]
  3. The distribution of neuropeptide Y gene expression in the chicken brain. Wang, X., Day, J.R., Vasilatos-Younken, R. Mol. Cell. Endocrinol. (2001) [Pubmed]
  4. Programming of appetite and type 2 diabetes. Martin-Gronert, M.S., Ozanne, S.E. Early Hum. Dev. (2005) [Pubmed]
  5. Clinical studies with corticotropin releasing factor: implications for the diagnosis and pathophysiology of depression, Cushing's disease, and adrenal insufficiency. Gold, P.W., Chrousos, G.P. Psychoneuroendocrinology (1985) [Pubmed]
  6. Constitutive ghrelin receptor activity as a signaling set-point in appetite regulation. Holst, B., Schwartz, T.W. Trends Pharmacol. Sci. (2004) [Pubmed]
  7. Nibbling at CRF receptor control of feeding and gastrocolonic motility. Zorrilla, E.P., Taché, Y., Koob, G.F. Trends Pharmacol. Sci. (2003) [Pubmed]
  8. Specific sequences in the N and C termini of apolipoprotein A-IV modulate its conformation and lipid association. Pearson, K., Tubb, M.R., Tanaka, M., Zhang, X.Q., Tso, P., Weinberg, R.B., Davidson, W.S. J. Biol. Chem. (2005) [Pubmed]
  9. Decreased postnatal survival and altered body weight regulation in procolipase-deficient mice. D'Agostino, D., Cordle, R.A., Kullman, J., Erlanson-Albertsson, C., Muglia, L.J., Lowe, M.E. J. Biol. Chem. (2002) [Pubmed]
  10. Association of estrogen receptor beta gene polymorphisms with bulimic disease in women. Nilsson, M., Naessén, S., Dahlman, I., Lindén Hirschberg, A., Gustafsson, J.A., Dahlman-Wright, K. Mol. Psychiatry (2004) [Pubmed]
  11. Glucocorticoid replacement, but not corticotropin-releasing hormone deficiency, prevents adrenalectomy-induced anorexia in mice. Jacobson, L. Endocrinology (1999) [Pubmed]
  12. Meal-induced changes in extracellular 5-HT in medial hypothalamus of lean (Fa/Fa) and obese (fa/fa) Zucker rats. De Fanti, B.A., Hamilton, J.S., Horwitz, B.A. Brain Res. (2001) [Pubmed]
  13. Evidence that nitric oxide stimulates feeding in the marsupial Sminthopsis crassicaudata. Vozzo, R., Wittert, G.A., Chapman, I.M., Fraser, R., Hope, P.J., Horowitz, M., Alshaher, M.M., Kumar, V.B., Morley, J.E. Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. (1999) [Pubmed]
  14. Leptin, adiponectin, and ghrelin dysregulation in chronic kidney disease. Guebre-Egziabher, F., Bernhard, J., Geelen, G., Malvoisin, E., Hadj-Aissa, A., Fouque, D. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. (2005) [Pubmed]
  15. Dietary effects on brain serotonin synthesis: relationship to appetite regulation. Fernstrom, J.D. Am. J. Clin. Nutr. (1985) [Pubmed]
  16. A novel inhibitor of gamma-aminobutyrate aminotransferase with anorectic activity. White, H.L., Howard, J.L., Cooper, B.R., Soroko, F.E., McDermed, J.D., Ingold, K.J., Maxwell, R.A. J. Neurochem. (1982) [Pubmed]
  17. Ghrelin, insulin sensitivity and postprandial glucose disposal in overweight and obese children. Maffeis, C., Bonadonna, R.C., Consolaro, A., Vettor, R., Banzato, C., Silvagni, D., Bogoni, G., Pellegrino, M., Tatò, L. Eur. J. Endocrinol. (2006) [Pubmed]
  18. Obesity is associated with genetic variants that alter dopamine availability. Need, A.C., Ahmadi, K.R., Spector, T.D., Goldstein, D.B. Ann. Hum. Genet. (2006) [Pubmed]
  19. Nicotine's effect on hypothalamic neurotransmitters and appetite regulation. Miyata, G., Meguid, M.M., Fetissov, S.O., Torelli, G.F., Kim, H.J. Surgery (1999) [Pubmed]
  20. Central relaxin-3 administration causes hyperphagia in male Wistar rats. McGowan, B.M., Stanley, S.A., Smith, K.L., White, N.E., Connolly, M.M., Thompson, E.L., Gardiner, J.V., Murphy, K.G., Ghatei, M.A., Bloom, S.R. Endocrinology (2005) [Pubmed]
  21. The effect of feeding on cerebrospinal fluid corticotropin-releasing hormone levels in humans. Kasckow, J.W., Hagan, M., Mulchahey, J.J., Baker, D.G., Ekhator, N.N., Strawn, J.R., Nicholson, W., Orth, D.N., Loosen, P.T., Geracioti, T.D. Brain Res. (2001) [Pubmed]
  22. Characterization of melanin concentrating hormone and preproorexin expression in the murine hypothalamus. Tritos, N.A., Mastaitis, J.W., Kokkotou, E., Maratos-Flier, E. Brain Res. (2001) [Pubmed]
  23. A role for agouti-related protein in appetite regulation in a species with continuous nutrient delivery. Wagner, C.G., McMahon, C.D., Marks, D.L., Daniel, J.A., Steele, B., Sartin, J.L. Neuroendocrinology (2004) [Pubmed]
  24. Agouti-related protein (83-132) is a competitive antagonist at the human melanocortin-4 receptor: no evidence for differential interactions with pro-opiomelanocortin-derived ligands. Pritchard, L.E., Armstrong, D., Davies, N., Oliver, R.L., Schmitz, C.A., Brennand, J.C., Wilkinson, G.F., White, A. J. Endocrinol. (2004) [Pubmed]
  25. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. Taheri, S., Lin, L., Austin, D., Young, T., Mignot, E. PLoS Med. (2004) [Pubmed]
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