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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Pathology, Surgical

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Disease relevance of Pathology, Surgical


High impact information on Pathology, Surgical


Chemical compound and disease context of Pathology, Surgical


Biological context of Pathology, Surgical


Anatomical context of Pathology, Surgical


Associations of Pathology, Surgical with chemical compounds

  • Immunoperoxidase staining of formalin-fixed and paraffin-embedded tissue sections with a monoclonal antibody to Ia-like antigens was chosen for assessment of the value of this marker for diagnosis in surgical pathology [21].
  • Determination of steroid hormone-dependency of tumours utilizing tissue sections. Survey of histochemical techniques and their application in surgical pathology [22].
  • When each of the biochemical quantities was combined with the surgical pathology data it was found that only urinary total hydroxy-proline to creatinine ratio improved the discrimination significantly (P less than 0.05) and that the effect was marginal [23].
  • This study was a detailed medical record review of 18 previously reported users of fenfluramine and phentermine, all with valve abnormalities on echocardiogram and 2 with surgical pathology [24].
  • All cases were diagnosed by the Surgical Pathology Service of the Laboratory of Pathology of the University of Pennsylvania, School of Veterinary Medicine, between January 1986 and March 1991 [25].

Gene context of Pathology, Surgical

  • We emphasize the interpretation of the AMACR immunohistochemical results in routine surgical pathology practice and also discuss the potential future applications of this marker and the possible role of AMACR in the pathogenesis of cancer development [26].
  • METHODS AND RESULTS: A panel of monoclonal antibodies against p53, p21 and cyclin D1 was applied to 19 bronchioloalveolar carcinomas (17 surgical pathology cases and two autopsies) from the tissue archives of St [27].
  • From these data we conclude that cyclin D3 and Topoisomerase II alpha appear to be additional markers for proliferation which can be used for prognosis index in surgical pathology of the pituitary [28].
  • The reactivity of the cadherin-specific antibodies with antigens in paraffin sections make them powerful and reliable markers in the practice of diagnostic surgical pathology [29].
  • This indicates that PCNA is stable under conditions routinely encountered in diagnostic surgical pathology and facilitates its potential use as a diagnostic proliferation marker [30].

Analytical, diagnostic and therapeutic context of Pathology, Surgical


  1. Radiation injury in surgical pathology. Part II. Alimentary tract. Berthrong, M., Fajardo, L.F. Am. J. Surg. Pathol. (1981) [Pubmed]
  2. Acute postoperative seizures after frontal lobe cortical resection for intractable partial epilepsy. Tigaran, S., Cascino, G.D., McClelland, R.L., So, E.L., Richard Marsh, W. Epilepsia (2003) [Pubmed]
  3. Comparison of HMB-45 monoclonal antibody and S-100 protein in the immunohistochemical diagnosis of melanoma. Ordóñez, N.G., Ji, X.L., Hickey, R.C. Am. J. Clin. Pathol. (1988) [Pubmed]
  4. Inflammatory bowel disease: the surgical pathology of Crohn's disease and ulcerative colitis. Price, A.B., Morson, B.C. Hum. Pathol. (1975) [Pubmed]
  5. The expression of epidermal growth factor receptor and transforming growth factor alpha in renal cell carcinoma. Lager, D.J., Slagel, D.D., Palechek, P.L. Mod. Pathol. (1994) [Pubmed]
  6. Cyclophosphamide-induced cystitis and bladder cancer in patients with Wegener granulomatosis. Talar-Williams, C., Hijazi, Y.M., Walther, M.M., Linehan, W.M., Hallahan, C.W., Lubensky, I., Kerr, G.S., Hoffman, G.S., Fauci, A.S., Sneller, M.C. Ann. Intern. Med. (1996) [Pubmed]
  7. Expression of a highly conserved protein, p27BBP, during the progression of human colorectal cancer. Sanvito, F., Vivoli, F., Gambini, S., Santambrogio, G., Catena, M., Viale, E., Veglia, F., Donadini, A., Biffo, S., Marchisio, P.C. Cancer Res. (2000) [Pubmed]
  8. Hepatocyte paraffin 1: a monoclonal antibody that reacts with hepatocytes and can be used for differential diagnosis of hepatic tumors. Wennerberg, A.E., Nalesnik, M.A., Coleman, W.B. Am. J. Pathol. (1993) [Pubmed]
  9. Adenoid cystic carcinoma of the breast. Data from the Connecticut Tumor Registry and a review of the literature. Sumpio, B.E., Jennings, T.A., Merino, M.J., Sullivan, P.D. Ann. Surg. (1987) [Pubmed]
  10. Painful Hashimoto's thyroiditis as an indication for thyroidectomy: clinical characteristics and outcome in seven patients. Kon, Y.C., DeGroot, L.J. J. Clin. Endocrinol. Metab. (2003) [Pubmed]
  11. Detection and characterization of atypical mycobacteria by the polymerase chain reaction. Cook, S.M., Bartos, R.E., Pierson, C.L., Frank, T.S. Diagn. Mol. Pathol. (1994) [Pubmed]
  12. Quality assurance for detection of estrogen and progesterone receptors by immunohistochemistry in Austrian pathology laboratories. Regitnig, P., Reiner, A., Dinges, H.P., Höfler, G., Müller-Holzner, E., Lax, S.F., Obrist, P., Rudas, M., Quehenberger, F. Virchows Arch. (2002) [Pubmed]
  13. Semiquantitative assessment of c-erbB-2 (HER-2) status in cytology specimens and tissue sections from breast carcinoma. Solomides, C.C., Zimmerman, R., Bibbo, M. Anal. Quant. Cytol. Histol. (1999) [Pubmed]
  14. Surgical pathology of cancer of the oral cavity and oropharynx. Brennan, C.T., Sessions, D.G., Spitznagel, E.L., Harvey, J.E. Laryngoscope (1991) [Pubmed]
  15. Amyloid in surgical pathology. Röcken, C., Sletten, K. Virchows Arch. (2003) [Pubmed]
  16. Surgical pathology of temporal lobe epilepsy. Experience with 216 cases. Wolf, H.K., Campos, M.G., Zentner, J., Hufnagel, A., Schramm, J., Elger, C.E., Wiestler, O.D. J. Neuropathol. Exp. Neurol. (1993) [Pubmed]
  17. CD45 (leukocyte common antigen) immunoreactivity in metastatic undifferentiated and neuroendocrine carcinoma: a potential diagnostic pitfall. Nandedkar, M.A., Palazzo, J., Abbondanzo, S.L., Lasota, J., Miettinen, M. Mod. Pathol. (1998) [Pubmed]
  18. Distribution of proliferating-cell nuclear antigen and epidermal growth factor receptor in intraepithelial squamous cell lesions of human bronchus. Yoneda, K. Mod. Pathol. (1994) [Pubmed]
  19. Etiology and significance of the optically clear nucleus. Baloch, Z.W., LiVolsi, V.A. Endocr. Pathol. (2002) [Pubmed]
  20. Chondroid syringoma. Cytokeratin 20 immunolocalization of Merkel cells and reappraisal of apocrine folliculo-sebaceous differentiation. Salama, M.E., Azam, M., Ma, C.K., Ormsby, A., Zarbo, R.J., Amin, M.B., Lee, M.W. Arch. Pathol. Lab. Med. (2004) [Pubmed]
  21. Immunoperoxidase staining for Ia-like antigens in paraffin-embedded tissues from human melanoma and lung carcinoma. Wilson, B.S., Herzig, M.A., Lloyd, R.V. Am. J. Pathol. (1984) [Pubmed]
  22. Determination of steroid hormone-dependency of tumours utilizing tissue sections. Survey of histochemical techniques and their application in surgical pathology. De Goeij, T.F., Bosman, F.T., Berns, E.M. J. Pathol. (1986) [Pubmed]
  23. The value of routine biochemical and surgical pathology quantities in predicting recurrence in high-risk patients following surgery for primary breast cancer. Winkel, P., Statland, B.E., Mouridsen, H., Sheike, O., Ammitsbøl, T. Am. J. Clin. Pathol. (1983) [Pubmed]
  24. Detailed examination of fenfluramine-phentermine users with valve abnormalities identified in Fargo, North Dakota. Kimmel, S.E., Keane, M.G., Crary, J.L., Jones, J., Kinman, J.L., Beare, J., Sammel, M., Sutton, M.S., Strom, B.L. Am. J. Cardiol. (1999) [Pubmed]
  25. Comparative histopathology of pemphigus foliaceus and superficial folliculitis in the dog. Kuhl, K.A., Shofer, F.S., Goldschmidt, M.H. Vet. Pathol. (1994) [Pubmed]
  26. Discovery and clinical application of a novel prostate cancer marker: alpha-methylacyl CoA racemase (P504S). Jiang, Z., Woda, B.A., Wu, C.L., Yang, X.J. Am. J. Clin. Pathol. (2004) [Pubmed]
  27. Nuclear expression of p53, p21 and cyclin D1 is increased in bronchioloalveolar carcinoma. McDonald, J.W., Pilgram, T.K. Histopathology (1999) [Pubmed]
  28. Cyclins D1 and D3 and topoisomerase II alpha in inactive pituitary adenomas. Saeger, W., Schreiber, S., Lüdecke, D.K. Endocr. Pathol. (2001) [Pubmed]
  29. Differential expression of N-cadherin in pleural mesotheliomas and E-cadherin in lung adenocarcinomas in formalin-fixed, paraffin-embedded tissues. Han, A.C., Peralta-Soler, A., Knudsen, K.A., Wheelock, M.J., Johnson, K.R., Salazar, H. Hum. Pathol. (1997) [Pubmed]
  30. Detection of proliferating cell nuclear antigen in diagnostic histopathology. Wolf, H.K., Dittrich, K.L. J. Histochem. Cytochem. (1992) [Pubmed]
  31. Evaluation of the performance and clinical impact of a rapid intraoperative parathyroid hormone assay in conjunction with preoperative imaging and concise parathyroidectomy. Johnson, L.R., Doherty, G., Lairmore, T., Moley, J.F., Brunt, L.M., Koenig, J., Scott, M.G. Clin. Chem. (2001) [Pubmed]
  32. Utility of microwave-citrate antigen retrieval in diagnostic immunohistochemistry. Brown, R.W., Chirala, R. Mod. Pathol. (1995) [Pubmed]
  33. Rapid intraoperative parathyroid hormone testing with surgical pathology correlations: the "chemical frozen section". Guarda, L.A. Am. J. Clin. Pathol. (2004) [Pubmed]
  34. Predicting risk of prostate specific antigen recurrence after radical prostatectomy with the Center for Prostate Disease Research and Cancer of the Prostate Strategic Urologic Research Endeavor databases. Moul, J.W., Connelly, R.R., Lubeck, D.P., Bauer, J.J., Sun, L., Flanders, S.C., Grossfeld, G.D., Carroll, P.R. J. Urol. (2001) [Pubmed]
  35. An evaluation of antigen retrieval procedures for immunoelectron microscopic classification of amyloid deposits. Röcken, C., Roessner, A. J. Histochem. Cytochem. (1999) [Pubmed]
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