Disease relevance of Tissue and Organ Procurement

• Brain death caused by Paracetamole and barbiturate overdose may not prohibit organ donation [1].
• For tissue donation, HIV infection screening relies on HIV p24 antigen and anti-HIV-1 and 2 antibody detection [2].
• Of 314 cases resulting from this review, organ procurement efforts yielded 10 patients with a diagnosis of brain tumor [3].

Psychiatry related information on Tissue and Organ Procurement

• "Hear a just cause, O Lord, attend to my cry": organ donation and pastoral care [4].

High impact information on Tissue and Organ Procurement

• These variables were: cell suspensions versus tissue fragments; incubation with 5-fluoro-2'-deoxyuridine; method of tissue procurement; location in the large bowel; and TLI distribution in different areas of the tumor [5].
• PURPOSE: Efforts to conclusively establish that human epidermal receptor (HER)-2 overexpression is important to androgen-dependent carcinoma of the prostate (AD-CaP) or to progression to androgen independence (AI-CaP) have failed because of variability in tissue procurement, antibodies, immunostaining procedures, and assessment methods [6].
• METHODS: Between 1988 and 1999, 117,501 adult kidney transplants were reported to Organ Procurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS) [7].
• As compared to all other high PRA patients within Southeastern Organ Procurement Foundation who were transplanted during the study period, they were more likely to be non-Caucasian, to be less well matched for private HLA-A, B, and DR antigens, and to have waited for a longer time than the other groups [8].
• Assuming no change is cold ischemia time, the potential number of 0 CREG, 0 DR mm, ABO-compatible transplants that could be achieved when an Organ Procurement Organization had 50-100 patients on their waiting list was calculated [9].

Biological context of Tissue and Organ Procurement

• The impact of haplotype match (HM), pretransplant transfusions, and cyclosporine use were examined for living-donor renal transplants performed among 49 centers in the South-Eastern Organ Procurement Foundation (SEOPF) from November 1983 to June 1988 with follow-up through March 1989 [10].
• METHODS AND RESULTS: The incidence of the ACE DD genotype was evaluated in 60 patients with severe PPH compared with two normal control populations, a group of healthy population-based controls (n=158) and subjects found suitable for cardiac organ donation (n=79) [11].

Associations of Tissue and Organ Procurement with chemical compounds

• Data collected prospectively on 3811 kidney transplants performed between June 1977 and July 1982 with follow-up to July 1984 by the 42 member institutions of the South-Eastern Organ Procurement foundation were analyzed to identify factors associated with graft and patient outcome in patients not receiving cyclosporine [12].
• Blood samples were drawn at 2-hr intervals from donor referral until organ procurement to analyze glucose, insulin, and C-peptide levels [13].
• In this report, we describe a case of multiple organ donation from a previously healthy individual who died from poisoning with the long-acting anticoagulant rodenticide, brodifacoum [14].
• After the elimination of methanol and the correction of metabolic disorders, organ donation was discussed [15].
• The use of desmopressin during organ procurement is associated with a higher rate of primary non-function of renal allografts [16].

Gene context of Tissue and Organ Procurement

• A survey on patients admitted in severe coma: implications for brain death identification and organ donation [17].
• In 1955, the Eye Bank of Canada introduced Canadians to the idea of postmortem tissue donation [18].
• We investigated the expression of the N-methyl-D-aspartate (NMDA) receptor, an important glutamate receptor, in brains from a population of well characterized schizophrenic patients who prospectively consented to tissue donation [19].
• DATA COLLECTION: Medicare and California Medicaid Program data were matched to the Organ Procurement and Transplantation Network Kidney Wait List files [20].
• OBJECTIVE: Past organ donation research has studied attitudes toward donation, predictors of signing donor cards, and distinguishing characteristics of donors vs. nondonors [21].

Analytical, diagnostic and therapeutic context of Tissue and Organ Procurement

• Effect of desmopressin substitution during organ procurement on early renal allograft function [16].
• METHODS: Comprehensive information relating to organ donation was obtained by a combination of structured interviews during visits to intensive care units (ICUs) and neurosurgical units, the use of detailed questionnaires sent to all UK ICUs, and from the register held by the United Kingdom Transplant Support Service Authority [22].
• Thyroid hormone replacement and its dosing should be decided by organ procurement organizations as part of treatment protocols [23].
• Public fund support through the ODC for organ procurement and the Kidney Foundation of Thailand is available for kidney transplantation [24].
• In June 2000, the Organ Transplantation Brain Death Act was approved by the Parliament, followed by the establishment of the Iranian Network for Transplantation Organ Procurement [25].

References