Disease relevance of Mercenaria

• Detection of hepatitis A virus in Mercenaria mercenaria by coupled reverse transcription and polymerase chain reaction [1].
• This study shows that the stone crab, M. mercenaria, survives severe hypoxia by a reliance on glycogen fermentation to lactate [2].
• One hundred and ten hard clams (Mercenaria spp.) harvested from the Calabar river estuary were examined for total platable heterotrophic bacteria and Vibrio spp. in their mantle fluids using estuarine salts agar and thiosulphate citrate bile salts sucrose agar plates respectively [3].
• Acute toxicity of tributyltin (TBT) to early life history stages of the hard shell clam, Mercenaria mercenaria [4].

High impact information on Mercenaria

• Mercenaria myosin and scallop pure hybrid myosin possessing Mercenaria regulatory light chains were reacted with various concentrations of 4-4'-dimaleimidylstilbene-2-2'-disulfonic acid (DMSDS) [5].
• This indicates the absence of free sulfhydryl groups in the regulatory light chain homodimer and suggests, therefore, that DMSDS links the two light chains together between translationally equivalent residues (Cys-50 of the Mercenaria regulatory light chain) [5].
• Treatment of the 14C-labeled product with alpha-fucosidase (Venus mercenaria) or weak acid at 100 degrees C for 2 h released 80-90% of the bound radioactive fucose [6].
• Scallop regulatory light chains cross-linked extensively (20 to 50%) with Mercenaria regulatory light chains (cysteine in position approximately 50) in solutions that induce rigor in skinned fibers (no ATP) and in relaxing solutions (ATP but no Ca2+) [7].
• An anti-cancer peptide was purified from the Mercenaria (Meretrix meretrix Linnaeus) by the method of chromatography on Sephadex G-25 and FPLC, and its molecular weight was determined to be 3147 Da by the way of MALDI-TOF mass spectrum [8].

Biological context of Mercenaria

• In C. virginica and Geukensia demissa phagocytosis or treatment with phorbol myristate acetate triggered significantly augmented, but kinetically dissimilar, ROI responses; however, no induction was recorded in two clam species (Mya arenaria and Mercenaria mercenaria) [9].
• The high selectivity and digestibility of algae particles by M. mercenaria, a potentially ingested food source, may play an important role in the bioavailability of chlorpyrifos in this animal [10].
• Hydrogen sulfide is synthesized in the gills of the clam Mercenaria mercenaria and acts seasonally to modulate branchial muscle contraction [11].
• However, the amount of the glutathione binding protein in the PCB-injected quahogs was found to decrease by approximately 50% in comparison to the glutathione binding protein in the control quahogs [12].

Anatomical context of Mercenaria

• In contrast, Mercenaria mercenaria hearts have weak cholinesterase activity, and the effects of ACh on this isolated myocardium were not potentiated by DMSO (2-20 microliters/ml) [13].
• Further in situ hybridization analysis and tyrosinase activity staining revealed that OT47 was expressed at the outer epithelial cells of the middle fold, different from early histological results in Mercenaria mercenaria, suggesting a different model of periostracum secretion in P. fucata [14].
• Calcium and small organic molecules (e.g., tyrosine, MW 181 Da) introduced into the extrapallial fluid (EPF) of the quahog Mercenaria mercenaria exhibit rapid fluxes across the outer mantle epithelium and are distributed throughout the circulatory system within 3 h [15].

Associations of Mercenaria with chemical compounds

• The storage and loss shear moduli, G' and G'', have been measured for dilute solutions of paramyosin from the clam Mercenaria mercenaria in water and glycerol--water mixtures containing potassium chloride and phosphate buffer [16].
• In addition, serotonin was assayed in the ventricles, auricles and heart-associated tissues in A. californica, M. mercenaria, H. multirugosus, and G. demissa with a sensitive radioenzymatic assay [17].
• Anticoagulantly active heparin from clam (Mercenaria mercenaria) [18].
• Analysis of glycosphingolipids by fluorophore-assisted carbohydrate electrophoresis using ceramide glycanase from Mercenaria mercenaria [19].
• Influence of alpha- and beta-adrenergic antagonists on dopamine-induced responses in the isolated heart of Mercenaria mercenaria [20].

Gene context of Mercenaria

• A new cytochrome P450 (CYP30) family identified in the clam, Mercenaria mercenaria [21].
• Dimers incorporating essential light chains were not formed upon reaction of DMSDS with Mercenaria myosin but some (less than 5%) essential light chain homodimers were obtained in the case of scallop hybrid myosin, probably occurring through relatively specific intermolecular associations within small myosin aggregates [5].
• Experiments were conducted with Y-organs in vitro from the crab, Menippe mercenaria, in the presence of labeled cholesterol, with or without the steroid 5 alpha-reductase inhibitor, L-645390 (Merck) [22].
• The activities of both the lateral and frontal cilia of Mercenaria mercenaria were unaffected, either by the two endogenous SCP-related peptides AMSFYFPRMamide and YFAFPRQamide, or by FMRFamide (all at 10(-6) M) [23].
• PCB residues in Mercenaria mercenaria from New Bedford Harbor, 1978 [24].

References