Disease relevance of Endocarditis, Bacterial

• Although often clinically benign, MVP can be associated with important accompanying sequelae, including mitral regurgitation, bacterial endocarditis, congestive heart failure, atrial fibrillation, and even sudden death [1].
• One patient had a vegetation from bacterial endocarditis, one had an intracardiac thrombus associated with myocarditis, three had rhabdomyomas (two patients with tuberous sclerosis) and one had a fibro-fatty nodule attached to the eustachian valve [2].
• Staphylococcus aureus, which has replaced Streptococcus viridans as the predominant etiology of fatal bacterial endocarditis, was frequently associated with glomerulonephritis, especially in parenteral drug abusers [3].
• Amyloid was found in 50 (82 per cent) of 61 valves showing degenerative calcific sclerosis and in 31 (53 per cent) of 58 valves showing post-rheumatic sclerosis but in none of 33 valves showing more acute disease processes (myxoid transformation, "stretch lesions," healed bacterial endocarditis) [4].
• The ability of tissue-type plasminogen activator (t-PA) to enhance the effect of antibiotics in the treatment of bacterial endocarditis was studied using plasma clots infected with Staphylococcus epidermidis as a model of infected endocardial vegetations [5].

High impact information on Endocarditis, Bacterial

• Erythromycin uniformly failed to protect animals from bacterial endocarditis but showed greater prophylactic efficacy when a low inoculum of streptococci was used [6].
• The estimated risk of contracting bacterial endocarditis prior to 30 years of age in a patient with medically-treated ventricular septal defect is 9.7%; the risk estimate for surgical patients in 2.0% [7].
• This report describes a patient with blood culture-negative bacterial endocarditis who presented with features suggestive of rheumatoid arthritis [8].
• The lack of diagnostic value of the indium scan in acute bacterial endocarditis [9].
• Wegener granulomatosis simulating bacterial endocarditis [10].

Chemical compound and disease context of Endocarditis, Bacterial

• However, two strains of S bovis recovered from two patients with bacterial endocarditis were resistant to the lethal effect of penicillin G [11].
• Imipenem, a potent new beta-lactam antibiotic, which is bactericidal against most pathogenic bacteria, and cilastatin, a dehydropeptidase inhibitor combined with imipenem to prevent the metabolism of imipenem in the kidney, were evaluated in the treatment of bacterial endocarditis [12].
• The unsuspected complications of bacterial endocarditis imaged by gallium-67 scanning [13].
• Pretargeting of bacterial endocarditis in rats with streptavidin and 111In-labeled biotin [14].
• Detection of bacterial endocarditis with technetium-99m-labeled antistaphylococcal antibody [15].

Anatomical context of Endocarditis, Bacterial

• It is conceivable that fibrin deposition on infected vegetations during bacterial endocarditis is mediated by thromboplastin synthesis by monocytes [16].
• Indium-111 leukocyte scintigraphic detection of mitral valve vegetations in active bacterial endocarditis [17].
• Other factors including bacterial endocarditis, concomitant ventricular septal defect repair, and aortic valve replacement did not independently influence long-term survival [18].
• Although MVP may progress later in life to frank mitral insufficiency requiring mitral valve repair or may predispose to bacterial endocarditis, in most cases it is a benign, idiopathic condition without serious consequences [19].
• A foal with vegetative bacterial endocarditis affecting the wall of the left atrium was treated successfully with cefotaxime, erythromycin, and rifampin [20].

Gene context of Endocarditis, Bacterial

• Streptococcus sanguis secretes CD14-binding proteins that stimulate cytokine synthesis: a clue to the pathogenesis of infective (bacterial) endocarditis [21]?
• MRSA infections cause the same spectrum of infection as MSSA infections, i.e., skin/soft tissue infections, bone/joint infections, central IV line infections, and acute bacterial endocarditis (native valve/prosthetic valve) [22].
• Suspected bacterial endocarditis. American College of Radiology. ACR Appropriateness Criteria [23].
• Bacterial endocarditis complicating systemic lupus erythematosus [24].
• The sera of patients with bacterial endocarditis frequently contain high levels of circulating immune complexes [25].

Analytical, diagnostic and therapeutic context of Endocarditis, Bacterial

• Circulating immune complexes associated with decreased complement-mediated inhibition of immune precipitation in sera from patients with bacterial endocarditis [25].
• We studied the relationship between the results of echocardiography for outpatients suspected of MVP, and two frequent medical decisions: treatment with beta blockers and the recommendation of antibiotic prophylaxis to prevent bacterial endocarditis [26].
• Chemoprophylaxis with oral amoxycillin against bacterial endocarditis: when should second doses be administered after dentistry [27]?
• There are no data to suggest that ototoxicity or nephrotoxicity will occur in the patient given a single intramuscular injection of gentamicin for the prophylaxis of bacterial endocarditis [28].

References