Gene Review:
WG - Wegener granulomatosis
Homo sapiens
Becker-Merok,
Kalaaji,
Haugbro,
Nikolaisen,
Nilsen,
Rekvig,
Nossent,
Pinto,
Dougados,
Stone,
Holbrook,
Marriott,
Tibbs,
Sejismundo,
Min,
Specks,
Merkel,
Spiera,
Davis,
St Clair,
McCune,
Ytterberg,
Allen,
Hoffman,
Jagiello,
Gencik,
Arning,
Wieczorek,
Kunstmann,
Csernok,
Gross,
Epplen,
Voswinkel,
Mueller,
Kraemer,
Lamprecht,
Herlyn,
Holl-Ulrich,
Feller,
Pitann,
Gause,
Gross,
Robert Geoffreys,
Kälsch,
Schmitt,
Breedijk,
Marinaki,
Weigerding,
Nebe,
Nemoto,
van der Woude,
Yard,
Birck,
Csernok,
Ai,
Gross,
Wicklein,
Petersen,
Lindner,
Lamprecht,
Holle,
Hellmich,
- Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway. Csernok, E., Ai, M., Gross, W.L., Wicklein, D., Petersen, A., Lindner, B., Lamprecht, P., Holle, J.U., Hellmich, B. Blood (2006)
- B lymphocyte maturation in Wegener's granulomatosis: a comparative analysis of VH genes from endonasal lesions. Voswinkel, J., Mueller, A., Kraemer, J.A., Lamprecht, P., Herlyn, K., Holl-Ulrich, K., Feller, A.C., Pitann, S., Gause, A., Gross, W.L. Ann. Rheum. Dis. (2006)
- MPO-ANCA-positive Wegener's granulomatosis presenting with hypertrophic cranial pachymeningitis: case report and review of the literature. Akahoshi, M., Yoshimoto, G., Nakashima, H., Miyake, K., Inoue, Y., Tanaka, Y., Tsukamoto, H., Horiuchi, T., Otsuka, T., Harada, M. Modern rheumatology / the Japan Rheumatism Association (2004)
- Incidence and disease associations of a proteinase 3-antineutrophil cytoplasmic antibody idiotype (5/7 Id) whose antiidiotype inhibits proteinase 3-antineutrophil cytoplasmic antibody antigen binding activity. Strunz, H.P., Csernok, E., Gross, W.L. Arthritis Rheum. (1997)
- Immunologic aspects of renal disease. Ambrus, J.L., Sridhar, N.R. JAMA (1997)
- Limited form of Wegener granulomatosis. Eye involvement as a major sign. Coutu, R.E., Klein, M., Lessell, S., Friedman, E., Snider, G.L. JAMA (1975)
- Wegener's granulomatosis: anti-proteinase 3 antibodies are potent inductors of human endothelial cell signaling and leakage response. Sibelius, U., Hattar, K., Schenkel, A., Noll, T., Csernok, E., Gross, W.L., Mayet, W.J., Piper, H.M., Seeger, W., Grimminger, F. J. Exp. Med. (1998)
- Neutrophil activation by anti-proteinase 3 antibodies in Wegener's granulomatosis: role of exogenous arachidonic acid and leukotriene B4 generation. Grimminger, F., Hattar, K., Papavassilis, C., Temmesfeld, B., Csernok, E., Gross, W.L., Seeger, W., Sibelius, U. J. Exp. Med. (1996)
- Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release. Role of surface proteinase-3, alpha1-antitrypsin, and Fcgamma receptors. Ralston, D.R., Marsh, C.B., Lowe, M.P., Wewers, M.D. J. Clin. Invest. (1997)
- The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis. Leavitt, R.Y., Fauci, A.S., Bloch, D.A., Michel, B.A., Hunder, G.G., Arend, W.P., Calabrese, L.H., Fries, J.F., Lie, J.T., Lightfoot, R.W. Arthritis Rheum. (1990)
- Use of methotrexate and glucocorticoids in the treatment of Wegener's granulomatosis. Long-term renal outcome in patients with glomerulonephritis. Langford, C.A., Talar-Williams, C., Sneller, M.C. Arthritis Rheum. (2000)
- New genomic region for Wegener's granulomatosis as revealed by an extended association screen with 202 apoptosis-related genes. Jagiello, P., Gencik, M., Arning, L., Wieczorek, S., Kunstmann, E., Csernok, E., Gross, W.L., Epplen, J.T. Hum. Genet. (2004)
- Renal histology in Chinese patients with anti-myeloperoxidase autoantibody-positive Wegener's granulomatosis. Chen, M., Yu, F., Wang, S.X., Zou, W.Z., Zhang, Y., Zhao, M.H., Wang, H.Y. Nephrol. Dial. Transplant. (2007)
- Proteinase 3, the target antigen of anticytoplasmic antibodies circulating in Wegener's granulomatosis. Immunolocalization in normal and pathologic tissues. Braun, M.G., Csernok, E., Gross, W.L., Müller-Hermelink, H.K. Am. J. Pathol. (1991)
- Solid malignancies among patients in the Wegener's Granulomatosis Etanercept Trial. Stone, J.H., Holbrook, J.T., Marriott, M.A., Tibbs, A.K., Sejismundo, L.P., Min, Y.I., Specks, U., Merkel, P.A., Spiera, R., Davis, J.C., St Clair, E.W., McCune, W.J., Ytterberg, S.R., Allen, N.B., Hoffman, G.S. Arthritis Rheum. (2006)
- In vivo effects of cyclic administration of 15-deoxyspergualin on leucocyte function in patients with Wegener's granulomatosis. K??lsch, A.I., Schmitt, W.H., Breedijk, A., Marinaki, S., Weigerding, S., Nebe, T.C., Nemoto, K., van der Woude, F.J., Yard, B.A., Birck, R. Clin. Exp. Immunol. (2006)
- Human endothelial cells express proteinase 3, the target antigen of anticytoplasmic antibodies in Wegener's granulomatosis. Mayet, W.J., Csernok, E., Szymkowiak, C., Gross, W.L., Meyer zum Büschenfelde, K.H. Blood (1993)
- An analysis of forty-two Wegener's granulomatosis patients treated with methotrexate and prednisone. Sneller, M.C., Hoffman, G.S., Talar-Williams, C., Kerr, G.S., Hallahan, C.W., Fauci, A.S. Arthritis Rheum. (1995)
- The treatment of Wegener's granulomatosis with glucocorticoids and methotrexate. Hoffman, G.S., Leavitt, R.Y., Kerr, G.S., Fauci, A.S. Arthritis Rheum. (1992)
- Analysis of autoantibody repertoires in small- and medium-sized vessels vasculitides. Evidence for specific perturbations in polyarteritis nodosa, microscopic polyangiitis, Churg-Strauss syndrome and Wegener's granulomatosis. Chanseaud, Y., Tamby, M.C., Guilpain, P., Reinbolt, J., Kambouchner, M., Boyer, N., Noël, L.H., Guillevin, L., Boissier, M.C., Mouthon, L. J. Autoimmun. (2005)
- Elevated interleukin-4 and interleukin-13 production by T cell lines from patients with Churg-Strauss syndrome. Kiene, M., Csernok, E., Müller, A., Metzler, C., Trabandt, A., Gross, W.L. Arthritis Rheum. (2001)
- Expression of chemokine and inhibitory receptors on natural killer cells: effect of immune activation and HIV viremia. Kottilil, S., Shin, K., Planta, M., McLaughlin, M., Hallahan, C.W., Ghany, M., Chun, T.W., Sneller, M.C., Fauci, A.S. J. Infect. Dis. (2004)
- Increased expression of the secretory leukocyte proteinase inhibitor in Wegener's granulomatosis. Ohlsson, S., Falk, R., Yang, J.J., Ohlsson, K., Segelmark, M., Wieslander, J. Clin. Exp. Immunol. (2003)
- Active Wegener's granulomatosis is associated with HLA-DR+ CD4+ T cells exhibiting an unbalanced Th1-type T cell cytokine pattern: reversal with IL-10. Lúdvíksson, B.R., Sneller, M.C., Chua, K.S., Talar-Williams, C., Langford, C.A., Ehrhardt, R.O., Fauci, A.S., Strober, W. J. Immunol. (1998)
- Accelerated atherosclerosis in patients with Wegener's granulomatosis. de Leeuw, K., Sanders, J.S., Stegeman, C., Smit, A., Kallenberg, C.G., Bijl, M. Ann. Rheum. Dis. (2005)
- Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis. Becker-Merok, A., Kalaaji, M., Haugbro, K., Nikolaisen, C., Nilsen, K., Rekvig, O.P., Nossent, J.C. Arthritis Res. Ther. (2006)
- Leflunomide in clinical practice. Pinto, P., Dougados, M. Acta reumatol??gica portuguesa (2006)
- The PTPN22 620W allele is a risk factor for Wegener's granulomatosis. Jagiello, P., Aries, P., Arning, L., Wagenleiter, S.E., Csernok, E., Hellmich, B., Gross, W.L., Epplen, J.T. Arthritis Rheum. (2005)
- Association of alkaline phosphatase with an autoantigen recognised by circulating anti-neutrophil antibodies in systemic vasculitis. Lockwood, C.M., Bakes, D., Jones, S., Whitaker, K.B., Moss, D.W., Savage, C.O. Lancet (1987)
- Prevalence of antineutrophil cytoplasmic antibodies in patients with various pulmonary diseases or multiorgan dysfunction. Vassilopoulos, D., Niles, J.L., Villa-Forte, A., Arroliga, A.C., Sullivan, E.J., Merkel, P.A., Hoffman, G.S. Arthritis Rheum. (2003)
- Wegener's granulomatosis: Possible role of environmental agents in its pathogenesis. Albert, D., Clarkin, C., Komoroski, J., Brensinger, C.M., Berlin, J.A. Arthritis Rheum. (2004)
- A staged approach to the treatment of Wegener's granulomatosis: induction of remission with glucocorticoids and daily cyclophosphamide switching to methotrexate for remission maintenance. Langford, C.A., Talar-Williams, C., Barron, K.S., Sneller, M.C. Arthritis Rheum. (1999)