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MeSH Review

Kidney Tubules, Distal

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Disease relevance of Kidney Tubules, Distal


High impact information on Kidney Tubules, Distal

  • Nox4 is an NADP(H) oxidase that generates signaling levels of superoxide and is found in greatest abundance in the distal renal tubules [5].
  • Synthetic parathyroid hormone fragments shortened at the amino terminus stimulate glucose-6-phosphate dehydrogenase activity in the distal renal tubule [6].
  • In addition, crystals were selectively retained in distal renal tubules containing cells with hyaluronan and osteopontin at their luminal surface [7].
  • OBJECTIVE: The thiazide-sensitive Na-Cl cotransporter (TSC) is located in the distal renal tubules [8].
  • Recent work suggests that a nicotinamide adenine dinucleotide (NAD+)-dependent 11 beta-OHSD isoform is expressed in distal renal tubule, in contrast with the hepatic isoform which is NAD(+)-phosphate (NADP+)-dependent [9].
  • Studies on frog skin, a model tissue with sodium transport properties resembling those of distal renal tubule, increases an cytosolic calcium caused a closure of apical sodium, channels, opening of basolateral chloride channels, and an overall decrese in sodium absorption [10]

Anatomical context of Kidney Tubules, Distal


Associations of Kidney Tubules, Distal with chemical compounds


Gene context of Kidney Tubules, Distal


Analytical, diagnostic and therapeutic context of Kidney Tubules, Distal



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