Chemical Compound Review:
chlorothiazide 4-chloro-10,10-dioxo- 10$l^{6}-thia-7,9...
Synonyms:
Aldoclor, Chlrosal, Clotride, Diuresal, Diurilix, ...
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- Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter. Simon, D.B., Nelson-Williams, C., Bia, M.J., Ellison, D., Karet, F.E., Molina, A.M., Vaara, I., Iwata, F., Cushner, H.M., Koolen, M., Gainza, F.J., Gitleman, H.J., Lifton, R.P. Nat. Genet. (1996)
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- Long-term bone loss in men: effects of genetic and environmental factors. Slemenda, C.W., Christian, J.C., Reed, T., Reister, T.K., Williams, C.J., Johnston, C.C. Ann. Intern. Med. (1992)
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- Drug-induced depression. Patten, S.B., Love, E.J. Psychotherapy and psychosomatics. (1997)
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- Furosemide promotes patent ductus arteriosus in premature infants with the respiratory-distress syndrome. Green, T.P., Thompson, T.R., Johnson, D.E., Lock, J.E. N. Engl. J. Med. (1983)
- Response of thiazide-induced hypokalemia to amiloride. Maronde, R.F., Milgrom, M., Vlachakis, N.D., Chan, L. JAMA (1983)
- Primary prevention with metoprolol in patients with hypertension. Mortality results from the MAPHY study. Wikstrand, J., Warnold, I., Olsson, G., Tuomilehto, J., Elmfeldt, D., Berglund, G. JAMA (1988)
- Evaluation of a new uricosuric diuretic--ticrynafen. Kosman, M.E. JAMA (1979)
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- WNK kinases regulate thiazide-sensitive Na-Cl cotransport. Yang, C.L., Angell, J., Mitchell, R., Ellison, D.H. J. Clin. Invest. (2003)
- Response of blood pressure, cardiac output, peripheral resistance, and exercise performance to substitution of calcium blocker for beta-blocker plus thiazide diuretic therapy in patients with both systemic hypertension and mild stable angina. Kawanishi, D.T., Reid, C.L., Gonzales, A., O'Rourke, R.A., Rahimtoola, S.H. Circulation (1989)
- Estradiol enhances thiazide-sensitive NaCl cotransporter density in the apical plasma membrane of the distal convoluted tubule in ovariectomized rats. Verlander, J.W., Tran, T.M., Zhang, L., Kaplan, M.R., Hebert, S.C. J. Clin. Invest. (1998)
- Thiazide diuretic drug receptors in rat kidney: identification with [3H]metolazone. Beaumont, K., Vaughn, D.A., Fanestil, D.D. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins. Yamauchi, K., Rai, T., Kobayashi, K., Sohara, E., Suzuki, T., Itoh, T., Suda, S., Hayama, A., Sasaki, S., Uchida, S. Proc. Natl. Acad. Sci. U.S.A. (2004)
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- Site and mechanism of action of trichlormethiazide in rabbit distal nephron segments perfused in vitro. Shimizu, T., Yoshitomi, K., Nakamura, M., Imai, M. J. Clin. Invest. (1988)
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- Antihypertensive drug therapy prevents cerebral microvascular abnormalities in hypertensive rats. Harper, S.L. Circ. Res. (1987)
- Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport. Yang, C.L., Zhu, X., Wang, Z., Subramanya, A.R., Ellison, D.H. J. Clin. Invest. (2005)
- Role of HSD11B2 polymorphisms in essential hypertension and the diuretic response to thiazides. Williams, T.A., Mulatero, P., Filigheddu, F., Troffa, C., Milan, A., Argiolas, G., Parpaglia, P.P., Veglio, F., Glorioso, N. Kidney Int. (2005)
- Axial heterogeneity of vasopressin-receptor subtypes along the human and mouse collecting duct. Carmosino, M., Brooks, H.L., Cai, Q., Davis, L.S., Opalenik, S., Hao, C., Breyer, M.D. Am. J. Physiol. Renal Physiol. (2007)
- Molecular cloning, expression pattern, and chromosomal localization of the human Na-Cl thiazide-sensitive cotransporter (SLC12A3). Mastroianni, N., De Fusco, M., Zollo, M., Arrigo, G., Zuffardi, O., Bettinelli, A., Ballabio, A., Casari, G. Genomics (1996)
- Low-dose hydrochlorothiazide and preservation of bone mineral density in older adults. A randomized, double-blind, placebo-controlled trial. LaCroix, A.Z., Ott, S.M., Ichikawa, L., Scholes, D., Barlow, W.E. Ann. Intern. Med. (2000)
- Thiazide-induced hyponatremia. Reproducibility by single dose rechallenge and an analysis of pathogenesis. Friedman, E., Shadel, M., Halkin, H., Farfel, Z. Ann. Intern. Med. (1989)