The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

von Willebrand Disease

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of von Willebrand Disease


Psychiatry related information on von Willebrand Disease


High impact information on von Willebrand Disease


Chemical compound and disease context of von Willebrand Disease


Biological context of von Willebrand Disease


Anatomical context of von Willebrand Disease


Gene context of von Willebrand Disease


Analytical, diagnostic and therapeutic context of von Willebrand Disease


  1. Platelet interaction with rabbit subendothelium in von Willebrand's disease: altered thrombus formation distinct from defective platelet adhesion. Turitto, V.T., Weiss, H.J., Baumgartner, H.R. J. Clin. Invest. (1984) [Pubmed]
  2. Platelet membrane glycoproteins implicated in ristocetin-induced aggregation. Studies of the proteins on platelets from patients with Bernard-Soulier syndrome and von Willebrand's disease. Jenkins, C.S., Phillips, D.R., Clemetson, K.J., Meyer, D., Larrieu, M.J., Lüscher, E.F. J. Clin. Invest. (1976) [Pubmed]
  3. Frequency of inherited bleeding disorders in women with menorrhagia. Kadir, R.A., Economides, D.L., Sabin, C.A., Owens, D., Lee, C.A. Lancet (1998) [Pubmed]
  4. Abnormal von Willebrand factor in bleeding angiodysplasias of the digestive tract. Veyradier, A., Balian, A., Wolf, M., Giraud, V., Montembault, S., Obert, B., Dagher, I., Chaput, J.C., Meyer, D., Naveau, S. Gastroenterology (2001) [Pubmed]
  5. Role of von Willebrand factor in arterial thrombosis. Studies in normal and von Willebrand disease pigs. Nichols, T.C., Bellinger, D.A., Reddick, R.L., Read, M.S., Koch, G.G., Brinkhous, K.M., Griggs, T.R. Circulation (1991) [Pubmed]
  6. Adolescent menstrual health. Adams Hillard, P.J. Pediatric endocrinology reviews : PER. (2006) [Pubmed]
  7. Medical, reproductive and psychosocial experiences of women diagnosed with von Willebrand's disease receiving care in haemophilia treatment centres: a case-control study. Kirtava, A., Drews, C., Lally, C., Dilley, A., Evatt, B. Haemophilia : the official journal of the World Federation of Hemophilia. (2003) [Pubmed]
  8. Acquired type I von Willebrand's disease associated with highly substituted hydroxyethyl starch. Jonville-Béra, A.P., Autret-Leca, E., Gruel, Y. N. Engl. J. Med. (2001) [Pubmed]
  9. Platelet aggregation induced by DDAVP in platelet-type von Willebrand's disease. Takahashi, H., Nagayama, R., Hattori, A., Shibata, A. N. Engl. J. Med. (1984) [Pubmed]
  10. Platelet aggregation induced by 1-desamino-8-D-arginine vasopressin (DDAVP) in Type IIB von Willebrand's disease. Holmberg, L., Nilsson, I.M., Borge, L., Gunnarsson, M., Sjörin, E. N. Engl. J. Med. (1983) [Pubmed]
  11. Heightened interaction between platelets and factor VIII/von Willebrand factor in a new subtype of von Willebrand's disease. Ruggeri, Z.M., Pareti, F.I., Mannucci, P.M., Ciavarella, N., Zimmerman, T.S. N. Engl. J. Med. (1980) [Pubmed]
  12. Expression of the phenotypic abnormality of platelet-type von Willebrand disease in a recombinant glycoprotein Ib alpha fragment. Murata, M., Russell, S.R., Ruggeri, Z.M., Ware, J. J. Clin. Invest. (1993) [Pubmed]
  13. Antihemophilic factor concentrate therapy in von Willebrand disease. Dissociation of bleeding-time factor and ristocetin-cofactor activities. Blatt, P.M., Brinkhous, K.M., Culp, H.R., Krauss, J.S., Roberts, H.R. JAMA (1976) [Pubmed]
  14. Inactivation of human factor VIII by activated protein C. Cofactor activity of protein S and protective effect of von Willebrand factor. Koedam, J.A., Meijers, J.C., Sixma, J.J., Bouma, B.N. J. Clin. Invest. (1988) [Pubmed]
  15. The effects of epinephrine infusion in patients with von Willebrand's disease. Rickles, F.R., Hoyer, L.W., Rick, M.E., Ahr, D.J. J. Clin. Invest. (1976) [Pubmed]
  16. Resistance to arteriosclerosis in pigs with von Willebrand's disease. Spontaneous and high cholesterol diet-induced arteriosclerosis. Fuster, W., Bowie, E.J., Lewis, J.C., Fass, D.N., Owen, C.A., Brown, A.L. J. Clin. Invest. (1978) [Pubmed]
  17. Aberrant multimeric structure of von Willebrand factor in a new variant of von Willebrand's disease (type IIC). Ruggeri, Z.M., Nilsson, I.M., Lombardi, R., Holmberg, L., Zimmerman, T.S. J. Clin. Invest. (1982) [Pubmed]
  18. Identification of a point mutation in type IIB von Willebrand disease illustrating the regulation of von Willebrand factor affinity for the platelet membrane glycoprotein Ib-IX receptor. Ware, J., Dent, J.A., Azuma, H., Sugimoto, M., Kyrle, P.A., Yoshioka, A., Ruggeri, Z.M. Proc. Natl. Acad. Sci. U.S.A. (1991) [Pubmed]
  19. Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease. Schneppenheim, R., Brassard, J., Krey, S., Budde, U., Kunicki, T.J., Holmberg, L., Ware, J., Ruggeri, Z.M. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  20. Functional analysis of a type IIB von Willebrand disease missense mutation: increased binding of large von Willebrand factor multimers to platelets. Cooney, K.A., Lyons, S.E., Ginsburg, D. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  21. Germ-line mosaicism for a valine-to-methionine substitution at residue 553 in the glycoprotein Ib-binding domain of von Willebrand factor, causing type IIB von Willebrand disease. Murray, E.W., Giles, A.R., Lillicrap, D. Am. J. Hum. Genet. (1992) [Pubmed]
  22. Aberrant dimerization of von Willebrand factor as the result of mutations in the carboxy-terminal region: identification of 3 mutations in members of 3 different families with type 2A (phenotype IID) von Willebrand disease. Enayat, M.S., Guilliatt, A.M., Surdhar, G.K., Jenkins, P.V., Pasi, K.J., Toh, C.H., Williams, M.D., Hill, F.G. Blood (2001) [Pubmed]
  23. von Willebrand factor synthesized by endothelial cells from a patient with type IIB von Willebrand disease supports platelet adhesion normally but has an increased affinity for platelets. de Groot, P.G., Federici, A.B., de Boer, H.C., d'Alessio, P., Mannucci, P.M., Sixma, J.J. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  24. Isoelectric focusing of human von Willebrand factor in urea-agarose gels. Fulcher, C.A., Ruggeri, Z.M., Zimmerman, T.S. Blood (1983) [Pubmed]
  25. Quantitative analysis of von Willebrand factor and its propeptide in plasma in acquired von Willebrand syndrome. van Genderen, P.J., Boertjes, R.C., van Mourik, J.A. Thromb. Haemost. (1998) [Pubmed]
  26. Gastrointestinal angiodysplasia in a patient with type 2 von Willebrand's disease and analysis of exon 28 of the von Willebrand factor gene. Satoh, Y., Kita, H., Kihira, K., Mutoh, H., Osawa, H., Satoh, K., Ido, K., Sakata, Y., Sugano, K. Am. J. Gastroenterol. (2004) [Pubmed]
  27. Endothelial cell-derived high molecular weight von Willebrand factor is converted into the plasma multimer pattern by granulocyte proteases. Tsai, H.M., Nagel, R.L., Hatcher, V.B., Sussman, I.I. Biochem. Biophys. Res. Commun. (1989) [Pubmed]
  28. Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization. Ginsburg, D., Handin, R.I., Bonthron, D.T., Donlon, T.A., Bruns, G.A., Latt, S.A., Orkin, S.H. Science (1985) [Pubmed]
  29. A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11. Mohlke, K.L., Nichols, W.C., Westrick, R.J., Novak, E.K., Cooney, K.A., Swank, R.T., Ginsburg, D. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  30. Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha. Cauwenberghs, N., Vanhoorelbeke, K., Vauterin, S., Westra, D.F., Romo, G., Huizinga, E.G., Lopez, J.A., Berndt, M.C., Harsfalvi, J., Deckmyn, H. Blood (2001) [Pubmed]
  31. Shear stress and von Willebrand factor in health and disease. Tsai, H.M. Semin. Thromb. Hemost. (2003) [Pubmed]
  32. Epitope mapping of the von Willebrand factor subunit distinguishes fragments present in normal and type IIA von Willebrand disease from those generated by plasmin. Berkowitz, S.D., Dent, J., Roberts, J., Fujimura, Y., Plow, E.F., Titani, K., Ruggeri, Z.M., Zimmerman, T.S. J. Clin. Invest. (1987) [Pubmed]
  33. The relationship of the properties of antihemophilic factor (factor VIII) that support ristocetin-induced platelet agglutination (factor VIIIR:RC) and platelet retention by glass beads as demonstrated by a monoclonal antibody. Ogata, K., Saito, H., Ratnoff, O.D. Blood (1983) [Pubmed]
  34. Treatment of von Willebrand disease with a high-purity factor VIII/von Willebrand factor concentrate: a prospective, multicenter study. Mannucci, P.M., Chediak, J., Hanna, W., Byrnes, J., Ledford, M., Ewenstein, B.M., Retzios, A.D., Kapelan, B.A., Schwartz, R.S., Kessler, C. Blood (2002) [Pubmed]
  35. Arteriosclerosis in normal and von Willebrand pigs: long-term prospective study and aortic transplantation study. Fuster, V., Fass, D.N., Kaye, M.P., Josa, M., Zinsmeister, A.R., Bowie, E.J. Circ. Res. (1982) [Pubmed]
  36. Severe type III von Willebrand's disease caused by deletion of exon 42 of the von Willebrand factor gene: family studies that identify carriers of the condition and a compound heterozygous individual. Peake, I.R., Liddell, M.B., Moodie, P., Standen, G., Mancuso, D.J., Tuley, E.A., Westfield, L.A., Sorace, J.M., Sadler, J.E., Verweij, C.L. Blood (1990) [Pubmed]
WikiGenes - Universities