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Chemical Compound Review

TITANIUM     titanium

Synonyms: Titanate, Titanio, Oremet, Titane, VTl-0, ...
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Disease relevance of titanium

  • Our results indicate that barium titanate ceramic shows a very high degree of biocompatibility as evidenced by the absence of inflammatory or foreign body reactions at the implant-tissue interface [1].
  • In order to study flow murmurs through atrial septal defects, right heart catheterization was performed on 48 patients of secundum type, four of primum type, and five of probe-patent foramen ovale, with the double-lumen phonocatheter of Lewis, at the tip of which barium titanate was mounted [2].
  • The existence of Ti metal phase can promote the dehydration and decomposition of HA ceramic phase into the more stable calcium phosphate phases, such as alpha-Ca(3)(PO(4))(2) (alpha-TCP) and Ca(4)O(PO(4))(2) at high temperatures [3].

High impact information on titanium


Biological context of titanium

  • A submicron size grain lead titanate piezoelectric ceramic was used to both reduce lateral coupling and keep the electrical impedance matched close to the 50 ohm receive electronics [9].

Anatomical context of titanium

  • In order to determine the effect of the surface composition, gingival fibroblasts were cultured for 14 d on polished substrate specimens of cp-titanium, TiAl6V4 and TiTa30 and examined for differences in shape [10].
  • Furthermore, actin staining showed that the cells on HA poorly formed stress fibers with weak polarity, whereas the cell on Ti possessed well-defined polarized stress fibers [8].
  • Islands of fibrocartilaginous tissue characterized the membrane around unstable HA implants, whereas fibrous connective tissue surrounded unstable Ti implants [11].
  • The superior fixation of unstable HA implants compared with unstable Ti implants may be ascribed to the presence of fibrocartilage, a higher collagen concentration, and radiating orientation of collagen fibers in the membrane [11].
  • The collagen concentration of the fibrous membranes was higher around unstable HA implants compared with Ti implants [11].

Associations of titanium with other chemical compounds


Gene context of titanium

  • Crystal structural parameters (21 positional parameters and nine isotropic Debye-Waller factors) of the intermediate phase of hexagonal barium titanate (h-BaTiO3) have been refined by a structure analysis method using convergent-beam electron diffraction (CBED); this method was developed by Tsuda & Tanaka [Acta Cryst. (1999), A55, 939-954] [18].
  • To verify the method, we used it to measure the R12 and R13 Kerr coefficients for a (100)-type single crystal of ferroelectric barium titanate (BaTiO3) at room temperature (23.5 degrees) [19].

Analytical, diagnostic and therapeutic context of titanium


  1. Piezoelectric ceramic implants: in vivo results. Park, J.B., Kelly, B.J., Kenner, G.H., von Recum, A.F., Grether, M.F., Coffeen, W.W. J. Biomed. Mater. Res. (1981) [Pubmed]
  2. Clinical study on the flow murmurs at the defect area of atrial septal defect by means of intracardiac phonocardiography. Kambe, T., Hibi, N., Ito, H., Arakawa, T., Nishimura, K. Am. Heart J. (1976) [Pubmed]
  3. Fabrication and characterization of hydroxyapatite reinforced with 20 vol % Ti particles for use as hard tissue replacement. Chu, C., Lin, P., Dong, Y., Xue, X., Zhu, J., Yin, Z. Journal of materials science. Materials in medicine. (2002) [Pubmed]
  4. Size- and shape-dependent transformation of nanosized titanate into analogous anatase titania nanostructures. Mao, Y., Wong, S.S. J. Am. Chem. Soc. (2006) [Pubmed]
  5. Phase transition between nanostructures of titanate and titanium dioxides via simple wet-chemical reactions. Zhu, H.Y., Lan, Y., Gao, X.P., Ringer, S.P., Zheng, Z.F., Song, D.Y., Zhao, J.C. J. Am. Chem. Soc. (2005) [Pubmed]
  6. Direct electrochemistry of myoglobin in titanate nanotubes film. Liu, A., Wei, M., Honma, I., Zhou, H. Anal. Chem. (2005) [Pubmed]
  7. Neutron powder diffraction study of Pb(HfxTi1-x)O3 ceramics (0.10<or=x<or=0.50). Frantti, J., Fujioka, Y., Eriksson, S., Hull, S., Kakihana, M. Inorganic chemistry. (2005) [Pubmed]
  8. Substrate affects the initial attachment and subsequent behavior of human osteoblastic cells (Saos-2). Okumura, A., Goto, M., Goto, T., Yoshinari, M., Masuko, S., Katsuki, T., Tanaka, T. Biomaterials (2001) [Pubmed]
  9. High-frequency ultrasound annular-array imaging. Part I: array design and fabrication. Snook, K.A., Hu, C.H., Shrout, T.R., Shung, K.K. IEEE transactions on ultrasonics, ferroelectrics, and frequency control. (2006) [Pubmed]
  10. Influence of the surface structure of titanium materials on the adhesion of fibroblasts. Eisenbarth, E., Meyle, J., Nachtigall, W., Breme, J. Biomaterials (1996) [Pubmed]
  11. Hydroxyapatite coating modifies implant membrane formation. Controlled micromotion studied in dogs. Søballe, K., Brockstedt-Rasmussen, H., Hansen, E.S., Bünger, C. Acta orthopaedica Scandinavica. (1992) [Pubmed]
  12. Real time observation of the hydrothermal crystallization of barium titanate using in situ neutron powder diffraction. Walton, R.I., Millange, F., Smith, R.I., Hansen, T.C., O'Hare, D. J. Am. Chem. Soc. (2001) [Pubmed]
  13. In vivo tensile testing of fluorapatite and hydroxylapatite plasma-sprayed coatings. Kangasniemi, I.M., Verheyen, C.C., van der Velde, E.A., de Groot, K. J. Biomed. Mater. Res. (1994) [Pubmed]
  14. Wet-chemical synthesis of crystalline BaTiO3 from stable chelated titanium complex: formation mechanism and dispersibility in organic solvents. Pramanik, N.C., Seok, S.I., Ahn, B.Y. Journal of colloid and interface science. (2006) [Pubmed]
  15. PMN-PT single crystal, high-frequency ultrasonic needle transducers for pulsed-wave Doppler application. Zhou, Q., Xu, X., Gottlieb, E.J., Sun, L., Cannata, J.M., Ameri, H., Humayun, M.S., Han, P., Shung, K.K. IEEE transactions on ultrasonics, ferroelectrics, and frequency control (2007) [Pubmed]
  16. Lattice parameters and structural phase transition of lanthanum titanate perovskite, La0.68(Ti0.95,Al0.05)O3. Ali, R., Yashima, M. Journal of synchrotron radiation. (2003) [Pubmed]
  17. Chemical control of photoexcited states in titanate nanostructures. Riss, A., Berger, T., Grothe, H., Bernardi, J., Diwald, O., Knözinger, E. Nano Lett. (2007) [Pubmed]
  18. Refinement of the crystal structural parameters of the intermediate phase of h-BaTiO3 using convergent-beam electron diffraction. Ogata, Y., Tsuda, K., Akishige, Y., Tanaka, M. Acta Crystallogr., A, Found. Crystallogr. (2004) [Pubmed]
  19. Method for measuring off-diagonal Kerr coefficients by using polarized light transmission. Melnichuk, M., Wood, L.T. Journal of the Optical Society of America. A, Optics, image science, and vision. (2005) [Pubmed]
  20. Enhanced catalytic activity of hemoglobin in organic solvents by layered titanate immobilization. Wang, Q., Gao, Q., Shi, J. J. Am. Chem. Soc. (2004) [Pubmed]
  21. Ferroelectricity in barium titanate quantum dots and wires. Fu, H., Bellaiche, L. Phys. Rev. Lett. (2003) [Pubmed]
  22. Facile Preparation Method of SiO(2)/PS/TiO(2) Multilayer Core-Shell Hybrid Microspheres. Zhou, J., Chen, M., Qiao, X., Wu, L. Langmuir : the ACS journal of surfaces and colloids (2006) [Pubmed]
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