Disease relevance of Heart Septum

• The 10 anomalies (group A, n=3; group B, n=7) that were detected only during the third trimester comprised aortic stenosis (n=2), cardiac rhabdomyoma (n=2), subaortic stenosis (n=1), tetralogy of Fallot (n= 1), aortic coarctation (n=1), sealed foramen ovale (n=1), ventricular septal defects (n=1), and hypertrophic cardiomyopathy (n=1) [1].
• No clear advantage for warfarin over aspirin exists for ischemic stroke in a setting of intracranial atheroma, patent cardiac foramen ovale, or elevated levels of antiphospholipid antibody [2].
• OBJECTIVE: To investigate the safety, efficacy, and clinical application of a new self centering device ("angel wings") for closure of secundum atrial septal defects (ASD II) and persistent foramen ovale in all age groups [3].
• Premature closure of foramen ovale and renal vein thrombosis in a stillborn twin homozygous for methylene tetrahydrofolate reductase gene polymorphism: a clinicopathologic case study [4].
• Dyspnea and arterial desaturation on upright position in elderly subjects is described as platypnea-orthodeoxia syndrome (POS) and in some patients it is due to right-to-left shunt across the atrial septal defect (ASD)/patent foramen ovale (PFO) [5].

High impact information on Heart Septum

• Assessment of flow events at the ductus venosus-inferior vena cava junction and at the foramen ovale in fetal sheep by use of multimodal ultrasound [6].
• A probe-patent foramen ovale was the presumed mechanism in four patients, and an unsuspected congenital atrial septal defect was found in the fifth patient [7].
• Thus, the diameter of the foramen ovale was the primary factor influencing arterial oxygenation during prostaglandin infusion [8].
• The use of stereotactically implanted intracranial depth (stereo-EEG), subdural strip and grid, and foramen ovale electrodes, as well as intraoperative electrocorticography and electrical brain stimulation ("functional mapping") at the Epilepsy Center University Hospital Zurich, from 1984 to 1998, is analyzed [9].
• CONCLUSIONS: Cerebral microembolism occurs frequently during tourniquet release, even in the absence of a patient foramen ovale [10].

Chemical compound and disease context of Heart Septum

• He was diagnosed as having persistent pulmonary hypertension of the newborn (PPHN) on the basis of persistent hypoxemia, despite continuous mechanical ventilatory support with 100% O2, and right-to-left shunting through the foramen ovale shown by Doppler echocardiography [11].

Anatomical context of Heart Septum

• Foramen ovale electrode (FOE) implantation is usually indicated in patients with mesial temporal lobe (MTL) epilepsy [12].
• Correction involved resection of all ductal tissue, primary anastomosis of the aortic arch, closure of the foramen ovale, and patch closure of the VSD [13].
• Because foramen ovale or ductus arteriosus shunts might have altered thermodilution cardiac index measurements in the stressed foals, the ratio, PAP/SAP was calculated to define relative circulatory reactivity [14].
• The most obvious effects specific to the Trifluralin treatment were an increase in occurrence of 14 ribs, an undoubled foramen ovale, and the occurrence of accessory foramina in the cervical vertebrae [15].
• The localization and direction of the foramen ovale accessorium led us to the conclusion that it housed some of the separate rootlets for the chewing muscles, in this case for mm pterygoidei, mm tensor veli palatini and tensor tympani [16].

Associations of Heart Septum with chemical compounds

• The model is consistent with the real dynamics of 45Ca washout from rabbit heart septum reported by Philipson and Langer (F Mol Cell Cardiol 11, 857 (1979)) [17].
• The placement of radiopaque markers over the commonly used "zygomatic points" in front of the ears provides landmarks on intraoperative radiological studies that facilitate localization of the foramen ovale [18].
• Right-to-left cardiac shunt through the foramen ovale was decreased by acetylcholine from 1.6 +/- 0.4 to 0.1 +/- 0.2 l/min but was not changed by sodium nitroprusside or PGI2 [19].
• Extension through the foramen ovale and involvement of the Meckel cave is best seen on coronal T1-weighted MR images, and nerve enhancement is best seen on fat-suppressed T1-weighted MR images [20].
• The preferential distribution of ductus venosus blood flow through the foramen ovale was enhanced (29.4 vs. 47.2%) and the proportion of O2 delivery to upper body organs derived from the ductus venosus increased (33.2 vs. 49.4%) [21].

Gene context of Heart Septum

• In patients with open ductus and bidirectional foramen ovale shunting (n = 3) ANF was 567 pg/mL and in those with left-to-right shunt 355 pg/mL (n 15, NS) [22].
• The opening area of the foramen ovale was 40% of the cross-section of the thoracic inferior vena cava, and the ratio of the long diameter to the short diameter was 2 to 1 [23].
• Perineural invasion of the intracranial segment of the mandibular and maxillary divisions (V2) might occur when an NPC spread along the V3 through the foramen ovale [24].
• The flap valve of the oval foramen is extensive and represents the embryonic primary atrial septum [25].
• Thus, primary pulmonary hypertension may result in findings similar to atrial septal defect on echocardiography, particularly if a foramen ovale is present [26].

Analytical, diagnostic and therapeutic context of Heart Septum

• Spectral analysis of interictal background EEG activity recorded through foramen ovale (FO) electrodes during monitoring (mean 5.8 days per patient) was studied in 10 medically refractory complex partial seizure (CPS) patients who were candidates for epilepsy surgery [27].
• In this situation, cross-sectional echocardiography often fails in differentiating the valve-incompetent oval foramen from an atrial septal defect [28].
• This may be a more consistent finding for the prenatal diagnosis of ostium secundum atrial septal defect than the previously reported bidirectional flow across the foramen ovale on color Doppler sonography [29].

References