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MeSH Review

Heart Septum

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Disease relevance of Heart Septum


High impact information on Heart Septum

  • Assessment of flow events at the ductus venosus-inferior vena cava junction and at the foramen ovale in fetal sheep by use of multimodal ultrasound [6].
  • A probe-patent foramen ovale was the presumed mechanism in four patients, and an unsuspected congenital atrial septal defect was found in the fifth patient [7].
  • Thus, the diameter of the foramen ovale was the primary factor influencing arterial oxygenation during prostaglandin infusion [8].
  • The use of stereotactically implanted intracranial depth (stereo-EEG), subdural strip and grid, and foramen ovale electrodes, as well as intraoperative electrocorticography and electrical brain stimulation ("functional mapping") at the Epilepsy Center University Hospital Zurich, from 1984 to 1998, is analyzed [9].
  • CONCLUSIONS: Cerebral microembolism occurs frequently during tourniquet release, even in the absence of a patient foramen ovale [10].

Chemical compound and disease context of Heart Septum


Anatomical context of Heart Septum


Associations of Heart Septum with chemical compounds

  • The model is consistent with the real dynamics of 45Ca washout from rabbit heart septum reported by Philipson and Langer (F Mol Cell Cardiol 11, 857 (1979)) [17].
  • The placement of radiopaque markers over the commonly used "zygomatic points" in front of the ears provides landmarks on intraoperative radiological studies that facilitate localization of the foramen ovale [18].
  • Right-to-left cardiac shunt through the foramen ovale was decreased by acetylcholine from 1.6 +/- 0.4 to 0.1 +/- 0.2 l/min but was not changed by sodium nitroprusside or PGI2 [19].
  • Extension through the foramen ovale and involvement of the Meckel cave is best seen on coronal T1-weighted MR images, and nerve enhancement is best seen on fat-suppressed T1-weighted MR images [20].
  • The preferential distribution of ductus venosus blood flow through the foramen ovale was enhanced (29.4 vs. 47.2%) and the proportion of O2 delivery to upper body organs derived from the ductus venosus increased (33.2 vs. 49.4%) [21].

Gene context of Heart Septum

  • In patients with open ductus and bidirectional foramen ovale shunting (n = 3) ANF was 567 pg/mL and in those with left-to-right shunt 355 pg/mL (n 15, NS) [22].
  • The opening area of the foramen ovale was 40% of the cross-section of the thoracic inferior vena cava, and the ratio of the long diameter to the short diameter was 2 to 1 [23].
  • Perineural invasion of the intracranial segment of the mandibular and maxillary divisions (V2) might occur when an NPC spread along the V3 through the foramen ovale [24].
  • The flap valve of the oval foramen is extensive and represents the embryonic primary atrial septum [25].
  • Thus, primary pulmonary hypertension may result in findings similar to atrial septal defect on echocardiography, particularly if a foramen ovale is present [26].

Analytical, diagnostic and therapeutic context of Heart Septum


  1. Congenital heart defects: natural course and in utero development. Yagel, S., Weissman, A., Rotstein, Z., Manor, M., Hegesh, J., Anteby, E., Lipitz, S., Achiron, R. Circulation (1997) [Pubmed]
  2. Anticoagulation and platelet antiaggregation therapy in stroke prevention. Chong, J.Y., Mohr, J.P. Curr. Opin. Neurol. (2005) [Pubmed]
  3. Percutaneous closure of secundum atrial septal defect with a new self centering device ("angel wings"). Rickers, C., Hamm, C., Stern, H., Hofmann, T., Franzen, O., Schräder, R., Sievert, H., Schranz, D., Michel-Behnke, I., Vogt, J., Kececioglu, D., Sebening, W., Eicken, A., Meyer, H., Matthies, W., Kleber, F., Hug, J., Weil, J. Heart (1998) [Pubmed]
  4. Premature closure of foramen ovale and renal vein thrombosis in a stillborn twin homozygous for methylene tetrahydrofolate reductase gene polymorphism: a clinicopathologic case study. Stanek, J., Bove, K.E., Bofinger, M., Needham, D., Saldana, L.R., Mutema, G.K., Meyer, R. Journal of perinatal medicine. (2000) [Pubmed]
  5. Platypnea-orthodeoxia: management by transcatheter buttoned device implantation. Rao, P.S., Palacios, I.F., Bach, R.G., Bitar, S.R., Sideris, E.B. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. (2001) [Pubmed]
  6. Assessment of flow events at the ductus venosus-inferior vena cava junction and at the foramen ovale in fetal sheep by use of multimodal ultrasound. Schmidt, K.G., Silverman, N.H., Rudolph, A.M. Circulation (1996) [Pubmed]
  7. Cerebral emboli of paradoxical origin. Jones, H.R., Caplan, L.R., Come, P.C., Swinton, N.W., Breslin, D.J. Ann. Neurol. (1983) [Pubmed]
  8. Role of balloon atrial septostomy before early arterial switch repair of transposition of the great arteries. Baylen, B.G., Grzeszczak, M., Gleason, M.E., Cyran, S.E., Weber, H.S., Myers, J., Waldhausen, J. J. Am. Coll. Cardiol. (1992) [Pubmed]
  9. Presurgical evaluation: current role of invasive EEG. Zumsteg, D., Wieser, H.G. Epilepsia (2000) [Pubmed]
  10. Cerebral microembolism diagnosed by transcranial Doppler during total knee arthroplasty: correlation with transesophageal echocardiography. Sulek, C.A., Davies, L.K., Enneking, F.K., Gearen, P.A., Lobato, E.B. Anesthesiology (1999) [Pubmed]
  11. Persistent pulmonary hypertension of the newborn associated with excessive pulmonary arterial muscularization: report of an autopsy case. Tsai, C.E., Chou, Y.H., Tsou, K.I., Huang, S.F., Lee, C.Y. J. Formos. Med. Assoc. (1993) [Pubmed]
  12. Analysis of electrical discharges made with the foramen ovale electrode recording technique in mesial temporal lobe epilepsy patients. Kim, O.J., Ahn, J.Y., Lee, B.I. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. (2004) [Pubmed]
  13. Primary definitive repair of type B interrupted aortic arch, ventricular septal defect, and patient ductus arteriosus. Early and late results. Moulton, A.L., Bowman, F.O. J. Thorac. Cardiovasc. Surg. (1981) [Pubmed]
  14. Pulmonary vascular reactivity of the newborn pony foal. Drummond, W.H., Sanchez, I.R., Kosch, P.C., Webb, A.I. Equine Vet. J. (1989) [Pubmed]
  15. Assessment of adult skeletons to detect prenatal exposure to 2,4,5-T or Trifluralin in mice. Beck, S.L. Teratology (1981) [Pubmed]
  16. Accessory oval foramen. Krmpotić-Nemanić, J., Vinter, I., Jalsovec, D. Ann. Anat. (2001) [Pubmed]
  17. The analysis of extracellular calcium exchange in perfused myocardium using mathematical modeling. Aliev, M.K. J. Mol. Cell. Cardiol. (1989) [Pubmed]
  18. Improved visualization of the foramen ovale for percutaneous approaches to the gasserian ganglion. Technical note. Gerber, A.M. J. Neurosurg. (1994) [Pubmed]
  19. Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension. Orton, E.C., Reeves, J.T., Stenmark, K.R. J. Appl. Physiol. (1988) [Pubmed]
  20. Imaging features and clinical significance of perineural spread or extension of head and neck tumors. Caldemeyer, K.S., Mathews, V.P., Righi, P.D., Smith, R.R. Radiographics : a review publication of the Radiological Society of North America, Inc. (1998) [Pubmed]
  21. Effects of cord compression on fetal blood flow distribution and O2 delivery. Itskovitz, J., LaGamma, E.F., Rudolph, A.M. Am. J. Physiol. (1987) [Pubmed]
  22. Correlation of patent ductus arteriosus shunting with plasma atrial natriuretic factor concentration in preterm infants with respiratory distress syndrome. Pesonen, E., Merritt, A.T., Heldt, G., Sahn, D.J., Elias, W., Tikkanen, I., Fyhrquist, F., Andersson, S. Pediatr. Res. (1990) [Pubmed]
  23. In situ morphology of the foramen ovale in the fetal and neonatal rat. Momma, K., Ito, T., Ando, M. Pediatr. Res. (1992) [Pubmed]
  24. Perineural invasion of the trigeminal nerve in patients with nasopharyngeal carcinoma. Imaging and clinical correlations. Su, C.Y., Lui, C.C. Cancer (1996) [Pubmed]
  25. The structure of the mouse heart in late fetal stages. Webb, S., Brown, N.A., Anderson, R.H. Anat. Embryol. (1996) [Pubmed]
  26. Primary pulmonary hypertension: M-mode and two-dimensional echocardiographic findings. Berger, B.C., Walinsky, P., Carey, P. Catheterization and cardiovascular diagnosis. (1983) [Pubmed]
  27. Regional "rigidity" of background EEG activity in the epileptogenic zone. Wang, J., Wieser, H.G. Epilepsia (1994) [Pubmed]
  28. Diagnostic criteria of interatrial defects: a single gate pulsed Doppler echocardiographic study. Oberhoffer, R., Lang, D. International journal of cardiology. (1989) [Pubmed]
  29. Prenatal diagnosis of ostium secundum atrial septal defect by M-mode fetal echocardiography. Salih, M., Demirel, L.C., Kurtay, G. Gynecol. Obstet. Invest. (1998) [Pubmed]
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