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Chemical Compound Review

AC1L99RF     2-[4-[(3R,10S,12S,13R)-3,12- dihydroxy-10...

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Disease relevance of Glycodeoxycholate


High impact information on Glycodeoxycholate


Chemical compound and disease context of Glycodeoxycholate


Biological context of Glycodeoxycholate


Anatomical context of Glycodeoxycholate


Associations of Glycodeoxycholate with other chemical compounds


Gene context of Glycodeoxycholate

  • A mixture of ten steroids was separated by microemulsion and micellar (SDS and glycodeoxycholate) electrokinetic chromatography systems [20].

Analytical, diagnostic and therapeutic context of Glycodeoxycholate


  1. Modification of intestinal flora with multispecies probiotics reduces bacterial translocation and improves clinical course in a rat model of acute pancreatitis. van Minnen, L.P., Timmerman, H.M., Lutgendorff, F., Verheem, A., Harmsen, W., Konstantinov, S.R., Smidt, H., Visser, M.R., Rijkers, G.T., Gooszen, H.G., Akkermans, L.M. Surgery (2007) [Pubmed]
  2. Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes. Patel, T., Bronk, S.F., Gores, G.J. J. Clin. Invest. (1994) [Pubmed]
  3. A model of hemorrhagic pancreatitis in cats--role of 16,16-dimethyl prostaglandin E2. Wedgwood, K.R., Farmer, R.C., Reber, H.A. Gastroenterology (1986) [Pubmed]
  4. Thermodynamic and molecular determinants of sterol solubilities in bile salt micelles. Armstrong, M.J., Carey, M.C. J. Lipid Res. (1987) [Pubmed]
  5. Biliary protein output by isolated perfused rat livers. Effects of bile salts. Barnwell, S.G., Godfrey, P.P., Lowe, P.J., Coleman, R. Biochem. J. (1983) [Pubmed]
  6. Specific one-stage method for assay of enterokinase activity by release of radiolabelled activation peptides from alpha-N-[3H]acetyl-trypsinogen and the effect of calcium ions on the enzyme activity. Magee, A.I., Grant, D.A., Hermon-Taylor, J., Offord, R.E. Biochem. J. (1981) [Pubmed]
  7. Pancreatic duct and microvascular permeability to macromolecules. The relation to acute pancreatitis. Reber, H.A. Scand. J. Gastroenterol. Suppl. (1985) [Pubmed]
  8. In vivo buccal delivery of the peptide drug buserelin with glycodeoxycholate as an absorption enhancer in pigs. Hoogstraate, A.J., Coos Verhoef, J., Pijpers, A., van Leengoed, L.A., Verheijden, J.H., Junginger, H.E., Boddé, H.E. Pharm. Res. (1996) [Pubmed]
  9. Binding characteristics of [3H]opioid ligands to active opioid binding sites solubilized from rat brain membranes by glycodeoxycholate and NaCl: the recovery of binding activity by dilution. Maruyama, M., Sugino, H., Akita, K., Hatanaka, H. Brain Res. (1987) [Pubmed]
  10. Recent advances in buccal drug delivery and absorption--in vitro and in vivo studies. Junginger, H.E., Hoogstraate, J.A., Verhoef, J.C. Journal of controlled release : official journal of the Controlled Release Society. (1999) [Pubmed]
  11. Effect of glucose on jejunal water and solute absorption in the presence of glycodeoxycholate and oleate in man. Brown, B.D., Ammon, H.V. Dig. Dis. Sci. (1981) [Pubmed]
  12. Solubilization and characterization of active opiate binding sites from mammalian brain. Howells, R.D., Gioannini, T.L., Hiller, J.M., Simon, E.J. J. Pharmacol. Exp. Ther. (1982) [Pubmed]
  13. Comparison of bile salt perturbation of duodenal and jejunal isolated brush-border membranes. Zhao, D.L., Hirst, B.H. Digestion (1990) [Pubmed]
  14. Transbuccal delivery of 2',3'-dideoxycytidine: in vitro permeation study and histological investigation. Xiang, J., Fang, X., Li, X. International journal of pharmaceutics. (2002) [Pubmed]
  15. Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum. Perez de la Cruz Moreno, M., Oth, M., Deferme, S., Lammert, F., Tack, J., Dressman, J., Augustijns, P. J. Pharm. Pharmacol. (2006) [Pubmed]
  16. In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine. Ikinci, G., Capan, Y., Senel, S., Alaaddinoğlu, E., Dalkara, T., Hincal, A.A. Die Pharmazie. (2000) [Pubmed]
  17. In-vivo buccal delivery of fluorescein isothiocyanate-dextran 4400 with glycodeoxycholate as an absorption enhancer in pigs. Hoogstraate, A.J., Verhoef, J.C., Tuk, B., Pijpers, A., van Leengoed, L.A., Verheijden, J.H., Junginger, H.E., Boddé, H.E. Journal of pharmaceutical sciences. (1996) [Pubmed]
  18. TR146 cells grown on filters as a model of human buccal epithelium: III. Permeability enhancement by different pH values, different osmolality values, and bile salts. Nielsen, H.M., Rassing, M.R. International journal of pharmaceutics. (1999) [Pubmed]
  19. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides. Illum, L., Fisher, A.N., Jabbal-Gill, I., Davis, S.S. International journal of pharmaceutics. (2001) [Pubmed]
  20. Microemulsion and micellar electrokinetic chromatography of steroids. Vomastová, L., Miksík, I., Deyl, Z. J. Chromatogr. B, Biomed. Appl. (1996) [Pubmed]
  21. Ca2+-mediated activation of human erythrocyte membrane Ca2+-ATPase. Au, K.S., Lee, M.F., Siu, Y.L. Biochim. Biophys. Acta (1989) [Pubmed]
  22. Glycodeoxycholate transport in brush border membrane vesicles isolated from rat jejunum and ileum. Wilson, F.A., Treanor, L.L. Biochim. Biophys. Acta (1979) [Pubmed]
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