Chemical Compound Review:
Taurochenodeoxycholate 2-[4-[(3R,5S,7R,10R,13R)-3,7- dihydroxy-10...
Synonyms:
- The mutant Eisai hyperbilirubinemic rat is resistant to bile acid-induced cholestasis and cytotoxicity. Hoshino, M., Hayakawa, T., Hirano, A., Kamiya, Y., Ohiwa, T., Tanaka, A., Kumai, T., Inagaki, T., Miyaji, M., Takeuchi, T. Hepatology (1994)
- Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: in vitro studies in rat hepatocytes and human erythrocytes. Heuman, D.M., Pandak, W.M., Hylemon, P.B., Vlahcevic, Z.R. Hepatology (1991)
- Effects of four taurine-conjugated bile acids on mucosal uptake and lymphatic absorption of cholesterol in the rat. Watt, S.M., Simmonds, W.J. J. Lipid Res. (1984)
- Apoptosis induced in rat hepatocytes by in vivo exposure to taurochenodeoxycholate. Chieco, P., Romagnoli, E., Aicardi, G., Suozzi, A., Forti, G.C., Roda, A. Histochem. J. (1997)
- Quantification of individual serum bile acids in patients with liver diseases using high-performance liquid chromatography. Okuda, H., Obata, H., Nakanishi, T., Hisamitsu, T., Matsubara, K., Watanabe, H. Hepatogastroenterology (1984)
- The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes. Takikawa, Y., Miyoshi, H., Rust, C., Roberts, P., Siegel, R., Mandal, P.K., Millikan, R.E., Gores, G.J. Gastroenterology (2001)
- Regulation of mucin secretion in human gallbladder epithelial cells: predominant role of calcium and protein kinase C. Dray-Charier, N., Paul, A., Combettes, L., Bouin, M., Mergey, M., Balladur, P., Capeau, J., Housset, C. Gastroenterology (1997)
- Isolation of the microtubule-vesicle motor kinesin from rat liver: selective inhibition by cholestatic bile acids. Marks, D.L., LaRusso, N.F., McNiven, M.A. Gastroenterology (1995)
- Spontaneous formation of pigmentary precipitates in bile salt-depleted rat bile and its prevention by micelle-forming bile salts. Angelico, M., De Sanctis, S.C., Gandin, C., Alvaro, D. Gastroenterology (1990)
- Taurine conjugate of ursodeoxycholate plays a major role in the hepatoprotective effect against cholestasis induced by taurochenodeoxycholate in rats. Tsukahara, K., Kanai, S., Ohta, M., Kitani, K. Liver (1993)
- Tauroursodeoxycholate and tauro-beta-muricholate exert cytoprotection by reducing intrahepatocyte taurochenodeoxycholate content. Ohiwa, T., Katagiri, K., Hoshino, M., Hayakawa, T., Nakai, T. Hepatology (1993)
- Bile acid transport and regulating functions in the human biliary epithelium. Chignard, N., Mergey, M., Veissière, D., Parc, R., Capeau, J., Poupon, R., Paul, A., Housset, C. Hepatology (2001)
- Calcium binding by monosulfate esters of taurochenodeoxycholate. Stevens, R.D., Lack, L., Killenberg, P.G. J. Lipid Res. (1991)
- Increased fecal bile acid excretion and changes in the circulating bile acid pool are involved in the hypocholesterolemic and gallstone-preventive actions of psyllium in hamsters. Trautwein, E.A., Kunath-Rau, A., Erbersdobler, H.F. J. Nutr. (1999)
- Bile acid inhibition of P-glycoprotein-mediated transport in multidrug-resistant cells and rat liver canalicular membrane vesicles. Mazzanti, R., Fantappié, O., Kamimoto, Y., Gatmaitan, Z., Gentilini, P., Arias, I.M. Hepatology (1994)
- Vasopressin reduces taurochenodeoxycholate-induced hepatotoxicity by lowering the hepatocyte taurochenodeoxycholate content. Nakazawa, T., Hoshino, M., Hayakawa, T., Tanaka, A., Ohiwa, T. J. Hepatol. (1996)
- Effect of taurochenodeoxycholate or tauroursodeoxycholate upon biliary output of phospholipids and plasma-membrane enzymes, and the extent of cell damage, in isolated perfused rat livers. Barnwell, S.G., Lowe, P.J., Coleman, R. Biochem. J. (1983)
- The effect of bile salts on the permeability and ultrastructure of the perfused, energy-depleted, rat blood-brain barrier. Greenwood, J., Adu, J., Davey, A.J., Abbott, N.J., Bradbury, M.W. J. Cereb. Blood Flow Metab. (1991)
- Studies of the relationship between the catalytic activity and binding of non-substrate ligands by the glutathione S-transferases. Boyer, T.D., Vessey, D.A., Holcomb, C., Saley, N. Biochem. J. (1984)
- Dietary fibers: V. Binding of bile salts, phospholipids and cholesterol from mixed micelles by bile acid sequestrants and dietary fibers. Vahouny, G.V., Tombes, R., Cassidy, M.M., Kritchevsky, D., Gallo, L.L. Lipids (1980)
- Role of bile salts and trypsin in the pathogenesis of experimental alkaline esophagitis. Salo, J.A., Kivilaakso, E. Surgery (1983)
- Mixed micelle properties and intestinal cholesterol uptake. Montet, J.C., Lindheimer, M., Reynier, M.O., Crotte, C., Bontemps, R., Gerolami, A. Biochimie (1982)
- Bile acids induce cyclooxygenase-2 expression in human pancreatic cancer cell lines. Tucker, O.N., Dannenberg, A.J., Yang, E.K., Fahey, T.J. Carcinogenesis (2004)
- Unique inhibition of bile salt-induced apoptosis by lecithins and cytoprotective bile salts in immortalized mouse cholangiocytes. Komichi, D., Tazuma, S., Nishioka, T., Hyogo, H., Une, M., Chayama, K. Dig. Dis. Sci. (2003)
- Inhibition of hepatocyte growth factor production in human fibroblasts by ursodeoxycholic acid. Hiramatsu, K., Matsumoto, Y., Miyazaki, M., Tsubouchi, H., Yamamoto, I., Gohda, E. Biol. Pharm. Bull. (2005)
- Characterization of the mouse bile salt export pump overexpressed in the baculovirus system. Noe, J., Hagenbuch, B., Meier, P.J., St-Pierre, M.V. Hepatology (2001)
- Multispecific amphipathic substrate transport by an organic anion transporter of human liver. Bossuyt, X., Müller, M., Meier, P.J. J. Hepatol. (1996)
- Identification of the 3-sulfate isomer as the major product of enzymatic sulfation of chenodeoxycholate conjugates. Kirkpatrick, R.B., Lack, L., Killenberg, P.G. J. Biol. Chem. (1980)
- Studies on steroids. CCXXVII. Separation and determination of bile acid 7- and 12-sulphates in urine by high-performance liquid chromatography with fluorescence labelling. Goto, J., Chikai, T., Nambara, T. J. Chromatogr. (1987)
- Treatment of experimentally induced cerebral atherothromboembolism in an animal model with streptokinase and taurochenodeoxycholate. Jeynes, B.J. Artery (1988)