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Chemical Compound Review

AGN-PC-006F3Z     [cyano-(3- phenoxyphenyl)methyl] 3-(2...

Synonyms: AG-G-59691, AC1L9DXT, CTK8F8871, 68085-85-8, 76703-62-3, ...
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Disease relevance of C10983

  • Mice were given 2.5 and 5.0 ppm cyhalothrin/kg body weight orally [1].
  • Thus, inhibitory avoidance tests carried out on rats at 90 days of age were capable of demonstrating neural toxicity of Cyhalothrin (0.02%) present only in the drinking water of dams during 21 days of lactation [2].

Psychiatry related information on C10983


High impact information on C10983


Biological context of C10983

  • Results showed that in vivo cyhalothrin treatment: (1) decreased macrophage spreading and phagocytosis indexes; (2) decreased macrophage nitric oxide (NO) production; (3) did not change spontaneous or PMA-induced macrophage H2O2 release [9].
  • Field trials on cattle confirmed that dipping in 0.007% cyhalothrin provided a high level of tick control and a minimum of 7 days protective period against reinfestation [10].
  • The prenatal effects of exposure to the insecticide cyhalothrin on the sexual maturation and sexual behavior of rats were investigated [11].
  • Laboratory and field populations were examined by both the PCR assay and conventional filter paper bioassays with the pyrethroid cyhalothrin to verify that populations containing greater proportions of individuals with the resistant sodium channel allele DNA sequence also had higher bioassay LC50 values [12].

Anatomical context of C10983


Associations of C10983 with other chemical compounds


Gene context of C10983


Analytical, diagnostic and therapeutic context of C10983


  1. Three-generation reproductive studies of a synthetic pyrethroid--cyhalothrin. Deshmukh, P.B. Toxicol. Lett. (1992) [Pubmed]
  2. Effects of exposure to a pyrethroid insecticide during lactation on the behavior of infant and adult rats. Moniz, A.C., Bernardi, M.M., Souza-Spinosa, H.S., Palermo-Neto, J. Braz. J. Med. Biol. Res. (1990) [Pubmed]
  3. Pyrethroid insecticides and pregnancy: effect on physical and behavioral development of rats. Gomes, M.d.a. .S., Bernardi, M.M., Spinosa, H.d.e. .S. Veterinary and human toxicology. (1991) [Pubmed]
  4. The pyrethroids permethrin and cyhalothrin are potent inhibitors of the mitochondrial complex I. Gassner, B., Wüthrich, A., Scholtysik, G., Solioz, M. J. Pharmacol. Exp. Ther. (1997) [Pubmed]
  5. Differential effects of pyrethroid insecticides on extracellular dopamine in the striatum of freely moving rats. Mubarak Hossain, M., Suzuki, T., Sato, N., Sato, I., Takewaki, T., Suzuki, K., Tachikawa, E., Kobayashi, H. Toxicol. Appl. Pharmacol. (2006) [Pubmed]
  6. Behavioral effects of type II pyrethroid cyhalothrin in rats. Righi, D.A., Palermo-Neto, J. Toxicol. Appl. Pharmacol. (2003) [Pubmed]
  7. Determination of pyrethroid residues in tobacco and cigarette smoke by capillary gas chromatography. Cai, J., Liu, B., Zhu, X., Su, Q. Journal of chromatography. A. (2002) [Pubmed]
  8. Neuromechanical effects of pyrethroids, allethrin, cyhalothrin and deltamethrin on the cholinergic processes in rat brain. Hossain, M.M., Suzuki, T., Sato, I., Takewaki, T., Suzuki, K., Kobayashi, H. Life Sci. (2005) [Pubmed]
  9. Effects of type II pyrethroid cyhalothrin on peritoneal macrophage activity in rats. Righi, D.A., Palermo-Neto, J. Toxicology (2005) [Pubmed]
  10. Cyhalothrin--a novel acaricidal and insecticidal synthetic pyrethroid for the control of the cattle tick (Boophilus microplus) and the buffalo fly (Haematobia irritans exigua). Stubbs, V.K., Wilshire, C., Webber, L.G. Aust. Vet. J. (1982) [Pubmed]
  11. Effects of prenatal pyrethroid insecticide exposure on the sexual development of rats. Gomes, M.d.a. .S., Bernardi, M.M., Spinosa, H.d.e. .S. Veterinary and human toxicology. (1991) [Pubmed]
  12. Screening of Haematobia irritans irritans (Diptera: Muscidae) populations for pyrethroid resistance-associated sodium channel gene mutations by using a polymerase chain reaction assay. Guerrero, F.D., Kunz, S.E., Kammlah, D. J. Med. Entomol. (1998) [Pubmed]
  13. Settling of insecticide from dip wash mixed with dam water and zinc sulphate and used to control sheep lice (Bovicola ovis). Morcombe, P.W., Hide, D.F., Young, G.E., Armstrong, E.W., Millar, L.E., Higgs, A.R. Aust. Vet. J. (1995) [Pubmed]
  14. Horn fly (Diptera: Muscidae) insecticide resistance in Kentucky and Arkansas. Cilek, J.E., Steelman, C.D., Knapp, F.W. J. Econ. Entomol. (1991) [Pubmed]
  15. Pyrethroid resistance in Australian field populations of the sheep body louse, Bovicola (Damalinia) ovis. Levot, G.W., Johnson, P.W., Hughes, P.B., Powis, K.J., Boray, J.C., Dawson, K.L. Med. Vet. Entomol. (1995) [Pubmed]
  16. Human blood and environmental media screening method for pesticides and polychlorinated biphenyl compounds using liquid extraction and gas chromatography-mass spectrometry analysis. Liu, S., Pleil, J.D. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2002) [Pubmed]
  17. Development of an enzyme-linked immunosorbent assay for the pyrethroid insecticide cyhalothrin. Gao, H., Ling, Y., Xu, T., Zhu, W., Jing, H., Sheng, W., Li, Q.X., Li, J. J. Agric. Food Chem. (2006) [Pubmed]
  18. Residual activity of cyhalothrin 20% EC on cattle as determined by mosquito bioassays. Vythilingam, I., Ridhawati, n.u.l.l., Sani, R.A., Singh, K.I. Southeast Asian J. Trop. Med. Public Health (1993) [Pubmed]
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