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Chemical Compound Review

Meothrin     [cyano-(3- phenoxyphenyl)methyl] 2,2,3,3...

Synonyms: Miothrin, Danimen, Danitol, Kilumal, Meiothrin, ...
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Disease relevance of Tame

  • The effects of aquatic humic acids on the bioconcentration and acute toxicity of fenpropathrin were evaluated using grass carp, Ctenopharyngodon idellus, in laboratory freshwater systems [1].
  • Pityriasis rosea (Herald spot) [2].
  • The bacterium Pseudomonas aeruginosa was isolated from the urban River Tame, Birmingham, UK, and planktonic bacteria were grown in sterile, sealed glass jars, in 100 ml growth media [3].
  • CLINICAL IMPLICATIONS: Tame horses in good condition and initially deprived of access of water for approximately 6 hours can be transported in groups in open trailers during hot, humid conditions for up to 24 hours before dehydration and fatigue become severe [4].
  • Indications for thoracotomy for removal of foreign body include (1) Poor endoscopic visualization of FB because of inflammatory tissue and (2) Herald bleeding during endoscopy [5].

High impact information on Tame


Chemical compound and disease context of Tame

  • Toxicity of a synthetic pyrethroid (Danitol 10 E.C.), methoprene (J.H.A.) and crude neem extract formulation (RB-b +PBO +Tx) in synergestic form was determined in laboratory by contact method against adults of Sitophilus oryzae [11].

Biological context of Tame


Anatomical context of Tame

  • All tested doses of meothrin increased the frequency of micronucleated polychromatic erythrocytes but the increase was statistically significant only at the two highest doses [10].

Associations of Tame with other chemical compounds


Gene context of Tame

  • Twenty-five survivors completed the Impact of Events Scale, a measure of intrusive reexperiencing and avoidant behaviour, approx. 7 months following the Herald of Free Enterprise disaster [17].
  • Relative to these pyrethroids, slightly lower concentrations of fenpropathrin were required to inhibit mitogenic responsiveness to Con A [18].

Analytical, diagnostic and therapeutic context of Tame


  1. Effect of natural dissolved humic material on bioavailability and acute toxicity of fenpropathrin to the grass carp, Ctenopharyngodon idellus. Wu, W.Z., Xu, Y., Schramm, K., Kettrup, A. Ecotoxicol. Environ. Saf. (1999) [Pubmed]
  2. Pityriasis rosea (Herald spot). Montes, L.F., Ceballos, R. J. Cutan. Pathol. (1977) [Pubmed]
  3. Characterisation of the fluorescence from freshwater, planktonic bacteria. Elliott, S., Lead, J.R., Baker, A. Water Res. (2006) [Pubmed]
  4. Stress responses of horses during a long period of transport in a commercial truck. Friend, T.H., Martin, M.T., Householder, D.D., Bushong, D.M. J. Am. Vet. Med. Assoc. (1998) [Pubmed]
  5. Pearls and perils in the management of prolonged, peculiar, penetrating esophageal foreign bodies in children. Gilchrist, B.F., Valerie, E.P., Nguyen, M., Coren, C., Klotz, D., Ramenofsky, M.L. J. Pediatr. Surg. (1997) [Pubmed]
  6. A morphogenesis checkpoint monitors the actin cytoskeleton in yeast. McMillan, J.N., Sia, R.A., Lew, D.J. J. Cell Biol. (1998) [Pubmed]
  7. Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Na v 1.8 sodium channels expressed in Xenopus oocytes. Choi, J.S., Soderlund, D.M. Toxicol. Appl. Pharmacol. (2006) [Pubmed]
  8. Induction of micronuclei by five pyrethroid insecticides in whole-blood and isolated human lymphocyte cultures. Surrallés, J., Xamena, N., Creus, A., Catalán, J., Norppa, H., Marcos, R. Mutat. Res. (1995) [Pubmed]
  9. Differential effects of pyrethroids on volume-sensitive anion and organic osmolyte pathways. Culliford, S.J., Borg, J.J., O'Brien, M.J., Kozlowski, R.Z. Clin. Exp. Pharmacol. Physiol. (2004) [Pubmed]
  10. Micronuclei formation in bone marrow cells of rats treated with meothrin (synthetic pyrethroid). Oraby, H.A. Journal of applied toxicology : JAT. (1997) [Pubmed]
  11. Determination of toxicity of danitol, methoprene and neem formulation against stored grain pest, sitophilus oryzae L. Tabassum, R., Jahan, M., Azmi, M.A., Naqvi, S.N. Pakistan journal of pharmaceutical sciences. (1992) [Pubmed]
  12. Selection for fenpropathrin and fenpropathrin + acephate resistance in the silverleaf whitefly (Homoptera: Aleyrodidae). Sivasupramaniam, S., Watson, T.F. J. Econ. Entomol. (2000) [Pubmed]
  13. Solid phase extraction method for rapid isolation and clean-up of some synthetic pyrethroid insecticides from human urine and plasma. Junting, L., Chuichang, F. Forensic Sci. Int. (1991) [Pubmed]
  14. Susceptibility of immature stages of Homalodisca coagulata (Hemiptera: Cicadellidae) to selected insecticides. Prabhaker, N., Castle, S.J., Toscano, N.C. J. Econ. Entomol. (2006) [Pubmed]
  15. When salaries aren't secret. Case, J. Harvard business review. (2001) [Pubmed]
  16. Studies on wide mesh netting impregnated with insecticides against Culex mosquitoes. Itoh, T., Shinjo, G., Kurihara, T. J. Am. Mosq. Control Assoc. (1986) [Pubmed]
  17. The Herald of Free Enterprise disaster: the relationship of intrusion and avoidance to subsequent depression and anxiety. Joseph, S., Yule, W., Williams, R. Behaviour research and therapy. (1994) [Pubmed]
  18. Effects of pyrethroids on lymphocyte mitogenic responsiveness. Stelzer, K.J., Gordon, M.A. Res. Commun. Chem. Pathol. Pharmacol. (1984) [Pubmed]
  19. Sudden infant death syndrome (SIDS) and disordered blood flow. Reid, G.M., Tervit, H. Med. Hypotheses (1991) [Pubmed]
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