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Chemical Compound Review

Bepantol     2,4-dihydroxy-N-(3- hydroxypropyl)-3,3...

Synonyms: Intrapan, Pantenol, Zentinic, Bepanthen, Panadon, ...
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Disease relevance of DL-Pantothenyl alcohol


High impact information on DL-Pantothenyl alcohol


Chemical compound and disease context of DL-Pantothenyl alcohol


Biological context of DL-Pantothenyl alcohol


Anatomical context of DL-Pantothenyl alcohol


Gene context of DL-Pantothenyl alcohol

  • In a randomized, double-blind, placebo-controlled study the effect of topical dexpanthenol (CAS 81-13-0) formulated in two different lipophilic vehicles on epidermal barrier function in vivo was carried out [19].

Analytical, diagnostic and therapeutic context of DL-Pantothenyl alcohol


  1. Topical corticosteroid therapy for acute radiation dermatitis: a prospective, randomized, double-blind study. Schmuth, M., Wimmer, M.A., Hofer, S., Sztankay, A., Weinlich, G., Linder, D.M., Elias, P.M., Fritsch, P.O., Fritsch, E. Br. J. Dermatol. (2002) [Pubmed]
  2. Dexpanthenol enemas in ulcerative colitis: a pilot study. Loftus, E.V., Tremaine, W.J., Nelson, R.A., Shoemaker, J.D., Sandborn, W.J., Phillips, S.F., Hasan, Y. Mayo Clin. Proc. (1997) [Pubmed]
  3. Effects of dexpanthenol with or without Aloe vera extract on radiation-induced oral mucositis: preclinical studies. Dörr, W., Schlichting, S., Bray, M.A., Flockhart, I.R., Hopewell, J.W. Int. J. Radiat. Biol. (2005) [Pubmed]
  4. Allergic contact dermatitis due to panthenol. Stables, G.I., Wilkinson, S.M. Contact Derm. (1998) [Pubmed]
  5. Provitamin B5 (pantothenol) inhibits growth of the intraerythrocytic malaria parasite. Saliba, K.J., Ferru, I., Kirk, K. Antimicrob. Agents Chemother. (2005) [Pubmed]
  6. Thêta-Cream versus Bepanthol lotion in breast cancer patients under radiotherapy. A new prophylactic agent in skin care? Röper, B., Kaisig, D., Auer, F., Mergen, E., Molls, M. Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]. (2004) [Pubmed]
  7. Dexpanthenol pastille and benzydamine hydrochloride spray for the prevention of post-operative sore throat. Gulhas, N., Canpolat, H., Cicek, M., Yologlu, S., Togal, T., Durmus, M., Ozcan Ersoy, M. Acta anaesthesiologica Scandinavica (2007) [Pubmed]
  8. Allergic contact dermatitis to panthenol and cocamidopropyl PG dimonium chloride phosphate in a facial hydrating lotion. Roberts, H., Williams, J., Tate, B. Contact Derm. (2006) [Pubmed]
  9. Efficacy of dexpanthenol in skin protection against irritation: a double-blind, placebo-controlled study. Biro, K., Thaçi, D., Ochsendorf, F.R., Kaufmann, R., Boehncke, W.H. Contact Derm. (2003) [Pubmed]
  10. Maintenance of hand eczema by oral pantothenic acid in a patient sensitized to dexpanthenol. Hemmer, W., Bracun, R., Wolf-Abdolvahab, S., Focke, M., Götz, M., Jarisch, R. Contact Derm. (1997) [Pubmed]
  11. Allergic contact reaction to dexpanthenol: lymphocyte transformation test and evidence for microsomal-dependent metabolism of the allergen. Hahn, C., Röseler, S., Fritzsche, R., Schneider, R., Merk, H.F. Contact Derm. (1993) [Pubmed]
  12. Prophylaxis with povidone-iodine against induction of oral mucositis by radiochemotherapy. Adamietz, I.A., Rahn, R., Böttcher, H.D., Schäfer, V., Reimer, K., Fleischer, W. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. (1998) [Pubmed]
  13. Colorimetric and fluorimetric methods for determination of panthenol in cosmetic and pharmaceutical formulation. Shehata, M.A., Tawakkol, S.M., Abdel Fattah, L.E. Journal of pharmaceutical and biomedical analysis. (2002) [Pubmed]
  14. Topical use of dexpanthenol in skin disorders. Ebner, F., Heller, A., Rippke, F., Tausch, I. American journal of clinical dermatology. (2002) [Pubmed]
  15. Evaluation of protective and therapeutic effects of dexpanthenol on nasal decongestants and preservatives: results of cytotoxic studies in vitro. Klöcker, N., Rudolph, P., Verse, T. American journal of rhinology. (2004) [Pubmed]
  16. Motility of the distal portion of the jejunum and pelvic flexure in ponies: effects of six drugs. Adams, S.B., Lamar, C.H., Masty, J. Am. J. Vet. Res. (1984) [Pubmed]
  17. Normal wound healing of the paranasal sinuses: clinical and experimental investigations. Hosemann, W., Wigand, M.E., Göde, U., Länger, F., Dunker, I. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. (1991) [Pubmed]
  18. Xenobiotics in vitro: the influence of L-cystine, pantothenat, and miliacin on metabolic and proliferative capacity of keratinocytes. Obrigkeit, D.H., Oepen, T., Jugert, F.K., Merk, H.F., Kubicki, J. Cutaneous and ocular toxicology. (2006) [Pubmed]
  19. Effect of topically applied dexpanthenol on epidermal barrier function and stratum corneum hydration. Results of a human in vivo study. Gehring, W., Gloor, M. Arzneimittel-Forschung. (2000) [Pubmed]
  20. Development and validation of reversed phase high performance liquid chromatography method for determination of dexpanthenol in pharmaceutical formulations. Kulikov, A.U., Zinchenko, A.A. Journal of pharmaceutical and biomedical analysis (2007) [Pubmed]
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