Chemical Compound Review:
sulmazol 8-(2-methoxy-4- methylsulfinyl-phenyl)-5,7...
Synonyms:
sulmazole, Sulmazolum, Vardax, Prestwick_1012, AR-L115, ...
- Effects of AR-L 115 BS (Sulmazol), a new cardiotonic agent, in coronary artery disease: improved ventricular wall motion, increased pump function and abolition of pacing-induced ischemia. Thormann, J., Schlepper, M., Kramer, W., Gottwik, M., Kindler, M. J. Am. Coll. Cardiol. (1983)
- The new positive inotrope sulmazole inhibits the function of guanine nucleotide regulatory proteins by affecting GTP turnover. Ramkumar, V., Stiles, G.L. Mol. Pharmacol. (1988)
- Molecular basis for the in vitro and in vivo cardiotonic activities of AR-L100. Hayes, J.S., Wyss, V.L., Wilson, H.C., Robertson, D.W., Kauffman, R.F. J. Pharmacol. Exp. Ther. (1986)
- A voltage clamp study of the effects of AR-L 115 BS on the pacemaker current of cardiac Purkinje fibres. Ziskoven, R., Achenbach, C., Wiemer, J., Hauswirth, O. Basic Res. Cardiol. (1982)
- Anthracyclines cardiotoxicity: antagonism by sulmazole, a new cardiotonic agent. Bossa, R., Galatulas, I. Anticancer Res. (1986)
- Phosphodiesterase-inhibiting properties of newer inotropic agents. Scholz, H., Meyer, W. Circulation (1986)
- Effects of new inotropic agents on Ca++ sensitivity of contractile proteins. Rüegg, J.C. Circulation (1986)
- Inotropic drugs and their mechanisms of action. Scholz, H. J. Am. Coll. Cardiol. (1984)
- The new cardiotonic agent sulmazole is an A1 adenosine receptor antagonist and functionally blocks the inhibitory regulator, Gi. Parsons, W.J., Ramkumar, V., Stiles, G.L. Mol. Pharmacol. (1988)
- Positive inotropic effects of milrinone, sulmazole and AR-L100 on isolated normal and infarcted hearts of the rat. Verrijk, R., Vleeming, W., van Rooij, H.H., Wemer, J., Porsius, A.J. Archives internationales de pharmacodynamie et de thérapie. (1989)
- The acute effect of a new positive inotropic agent (AR-L 115 BS) on cardiac hemodynamics and contractility in patients with severe chronic congestive heart failure. Hauf, G.F., Bubenheimer, P., Roskamm, H. Arzneimittel-Forschung. (1981)
- Pharmacological characterization of a new Ca(2+) sensitizer. Dorigo, P., Floreani, M., Santostasi, G., Maragno, I., Danieli-Betto, D., Germinario, E., Magno, S.M., Primofiore, G., Marini, A.M., Da Settimo, F. J. Pharmacol. Exp. Ther. (2000)
- A comparative study of the cardiovascular and biochemical actions of the imidazo [4,5b] pyridine sulmazole and an imidazo [4,5c] pyridine analogue, BW A746C. Allan, G., Cambridge, D., Follenfant, M.J., Stone, D., Whiting, M.V. Br. J. Pharmacol. (1988)
- Nonlinear pharmacokinetics of the new positive inotropic agent sulmazole in the dog. Garrett, E.R., Roth, W. Journal of pharmaceutical sciences. (1983)
- "Low" concentrations of sodium fluoride inhibit neurotransmitter release from the guinea-pig superior cervical ganglion. Borasio, P.G., Cervellati, F., Pavan, B., Pareschi, M.C. Neurosci. Lett. (2004)
- Activation of the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel by analogues of sulmazole. McGarry, S.J., Williams, A.J. Br. J. Pharmacol. (1994)
- Sulmazole (AR-L 115BS) activates the sheep cardiac muscle sarcoplasmic reticulum calcium-release channel in the presence and absence of calcium. Williams, A.J., Holmberg, S.R. J. Membr. Biol. (1990)
- Rapid, sensitive and fully automated high-performance liquid chromatographic assay with fluorescence detection for sulmazole and metabolites. Roth, W. J. Chromatogr. (1983)
- Sulmazole effects on PGE2 and D-Ala2-Met-enkephalinamide modulation of cyclic AMP synthesis and neurotransmitter release in a sympathetic ganglion. Borasio, P.G., Cervellati, F., Fabbri, E. Neurosci. Lett. (1992)
- Cardiotonic agents. 1. Synthesis and structure-activity relationships in a new class of 3-, 4-, and 5-pyridyl-2(1H)-quinolone derivatives. Leclerc, G., Marciniak, G., Decker, N., Schwartz, J. J. Med. Chem. (1986)
- MCI-154, a novel cardiotonic agent, reverses the acidic pH-induced decrease in responses of cardiac myofilaments to Ca++: comparison with sulmazole and pimobendan. Kitada, Y., Abe, Y., Narimatsu, A., Tobe, A. J. Pharmacol. Exp. Ther. (1991)
- Effects of the calcium antagonists perhexiline and cinnarizine on vascular and cardiac contractile protein function. Silver, P.J., Dachiw, J., Ambrose, J.M., Pinto, P.B. J. Pharmacol. Exp. Ther. (1985)
- Comparison of the effects of MCI-154, a new cardiotonic agent, and some Ca2+-sensitizing agents on the response of the contractile system to Ca2+ in skinned cardiac muscle. Kitada, Y., Morita, M., Narimatsu, A. Jpn. J. Pharmacol. (1989)
- Imidazopyridines: roles of pyridine nitrogen position and methylsulfinyl oxygen for in vitro positive inotropic mechanism and chronotropic activity. Honerjäger, P., Klockow, M., Schönsteiner, G., Jonas, R. J. Cardiovasc. Pharmacol. (1989)
- Mechanisms of monooxygenase induction and inhibition. Netter, K.J. Pharmacol. Ther. (1987)
- Effects of AR-L 115 BS on arterial and venous muscle tone in vitro. Nguyen, D.H., Rüdel, R., Voss, U. Arzneimittel-Forschung. (1981)
- The effect of AR-L 115 BS on left ventricular function in patients with coronary heart disease and dilated cardiomyopathy. Stauch, M., Sigel, H., Seibold, H., Nechwatal, W. Klin. Wochenschr. (1983)
- Comparative cardiovascular effects of three benzimidazole derivatives, AR-L 57 BS, AR-L 100 BS, and AR-L 115 BS. Diederen, W., Kadatz, R. Arzneimittel-Forschung. (1981)
- A new orally active positive inotropic substance: AR-L 115 BS. Ruffmann, K.D., Mehmel, H.C., Kübler, W. Arzneimittel-Forschung. (1981)
- A double blind crossover tolerance study of AR-L 115 BS in health volunteers. Van Wayjen, R.G., vd Ende, A., Schuijt, C. Arzneimittel-Forschung. (1981)
- Effects of AR-L 115 BS on hemodynamics, myocardial oxygen consumption and cardiac pumping efficiency. Hellige, G., Baller, D., Ensink, F.B., Zipfel, J., Wolpers, H.G., Bretschneider, H.J. Arzneimittel-Forschung. (1981)