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Chemical Compound Review

BAIB     3-amino-2-methyl-propanoic acid

Synonyms: PubChem21922, CHEBI:27389, HMDB03911, ANW-63292, bmse000828, ...
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Disease relevance of beta-Aminoisobutyric acid


High impact information on beta-Aminoisobutyric acid


Chemical compound and disease context of beta-Aminoisobutyric acid


Biological context of beta-Aminoisobutyric acid


Anatomical context of beta-Aminoisobutyric acid


Associations of beta-Aminoisobutyric acid with other chemical compounds


Gene context of beta-Aminoisobutyric acid


Analytical, diagnostic and therapeutic context of beta-Aminoisobutyric acid


  1. Altered excretion of modified nucleosides and beta-aminoisobutyric acid in subjects with acquired immunodeficiency syndrome or at risk for acquired immunodeficiency syndrome. Borek, E., Sharma, O.K., Buschman, F.L., Cohn, D.L., Penley, K.A., Judson, F.N., Dobozin, B.S., Horsburgh, C.R., Kirkpatrick, C.H. Cancer Res. (1986) [Pubmed]
  2. Elevation of serum levels of beta-aminoisobutyric acid in uremic patients and the toxicity of the amino acid. Gejyo, F., Kinoshita, Y., Ikenaka, T. Clin. Nephrol. (1977) [Pubmed]
  3. beta-Aminoisobutyric acid as a marker of thymine catabolism in malignancy. van Gennip, A.H., van Bree-Blom, E.J., Abeling, N.G., van Erven, A.J., Voûte, P.A. Clin. Chim. Acta (1987) [Pubmed]
  4. Urinary amino acid excretion by patients with beta-thalassemia. Blackburn, P., Peterson, C.M. Clin. Chim. Acta (1977) [Pubmed]
  5. beta-Ureidopropionase deficiency: an inborn error of pyrimidine degradation associated with neurological abnormalities. van Kuilenburg, A.B., Meinsma, R., Beke, E., Assmann, B., Ribes, A., Lorente, I., Busch, R., Mayatepek, E., Abeling, N.G., van Cruchten, A., Stroomer, A.E., van Lenthe, H., Zoetekouw, L., Kulik, W., Hoffmann, G.F., Voit, T., Wevers, R.A., Rutsch, F., van Gennip, A.H. Hum. Mol. Genet. (2004) [Pubmed]
  6. Mitochondrial and metabolic effects of nucleoside reverse transcriptase inhibitors (NRTIs) in mice receiving one of five single- and three dual-NRTI treatments. Note, R., Maisonneuve, C., Lettéron, P., Peytavin, G., Djouadi, F., Igoudjil, A., Guimont, M.C., Biour, M., Pessayre, D., Fromenty, B. Antimicrob. Agents Chemother. (2003) [Pubmed]
  7. In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine. Cretton, E.M., Zhou, Z., Kidd, L.B., McClure, H.M., Kaul, S., Hitchcock, M.J., Sommadossi, J.P. Antimicrob. Agents Chemother. (1993) [Pubmed]
  8. Plasma free amino acids and their metabolites in Taiwanese patients on hemodialysis and continuous ambulatory peritoneal dialysis. Chuang, C.K., Lin, S.P., Chen, H.H., Chen, Y.C., Wang, T.J., Shieh, W.H., Wu, C.J. Clin. Chim. Acta (2006) [Pubmed]
  9. Thymidine incorporation into Rhizobium meliloti. Behki, R.M., Lesley, S.M. Can. J. Microbiol. (1979) [Pubmed]
  10. Genetic Analysis of the First 4 Patients with beta-Ureidopropionase Deficiency. van Kuilenburg, A.B., Meinsma, R., Assman, B., Hoffman, G.F., Voit, T., Ribes, A., Lorente, I., Busch, R., Mayatepek, E., Abeling, N.G., Wevers, R.A., Rutsch, F., van Gennip, A.H. Nucleosides Nucleotides Nucleic Acids (2006) [Pubmed]
  11. Transplacental pharmacokinetics and fetal distribution of 2', 3'-didehydro-3'-deoxythymidine (d4T) and its metabolites in late-term rhesus macaques. Patterson, T.A., Binienda, Z.K., Newport, G.D., Lipe, G.W., Gillam, M.P., Slikker, W., Sandberg, J.A. Teratology (2000) [Pubmed]
  12. Excretion patterns of pseudouridine and beta-aminoisobutyric acid in patients with tumours of the upper urinary tract. Kvist, E., Sjølin, K.E., Iversen, J. Scandinavian journal of urology and nephrology. (1990) [Pubmed]
  13. DNA degradation in the kidney of folic acid-treated guinea pigs. Zeis, P.M., Tzaki, M., Nakopoulou, L., Nicolaidou, P., Kavazarakis, E., Messaritaki, A., Moustaki, M., Zeis, M.P., Gourgiotis, D. Cytobios (2000) [Pubmed]
  14. Demonstration and preliminary characterization of an enzyme capable of the further metabolism of the thymidine catabolite, beta-aminoisobutyric acid, in Tetrahymena pyriformis strain GL1. Niemann, M.A., Berech, J. J. Protozool. (1981) [Pubmed]
  15. Renal secretion of amino acids in ophidian reptiles. Benyajati, S., Dantzler, W.H. Am. J. Physiol. (1986) [Pubmed]
  16. Identification of beta-aminoisobutyric acid in uremic serum. Gejyo, F., Kinoshita, Y., Ikenaka, T. Clin. Chim. Acta (1976) [Pubmed]
  17. A Pivotal Role for beta-Aminoisobutyric Acid and Oxidative Stress in Dihydropyrimidine Dehydrogenase Deficiency? van Kuilenburg, A.B., Stroomer, A.E., Abeling, N.G., van Gennip, A.H. Nucleosides Nucleotides Nucleic Acids (2006) [Pubmed]
  18. Rapid determination of beta-aminoisobutyric acid by reversed-phase high-performance liquid chromatography. Ladrón de Guevara, O., Cortinas de Nava, C., Padilla, P., Espinosa, J., Cebrian, M., García, L. J. Chromatogr. (1990) [Pubmed]
  19. A feasibility study in the development of biological markers for ovarian cancer. Waalkes, T.P., Rosenshein, N.B., Shaper, J.H., Ettinger, D.S., Woo, K.B., Paone, J.F., Gehrke, C.W. Journal of surgical oncology. (1982) [Pubmed]
  20. Correlations of beta-aminoisobutyric acid in 8 hour and 24 hour urinary samples determined by dual column gas chromatography. Sjölin, K.E., Nyholm, K.K. Biomedicine / [publiée pour l'A.A.I.C.I.G.]. (1980) [Pubmed]
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