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MeSH Review

Aorta, Abdominal

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Disease relevance of Aorta, Abdominal


Psychiatry related information on Aorta, Abdominal


High impact information on Aorta, Abdominal


Chemical compound and disease context of Aorta, Abdominal

  • Rabbits on 2% cholesterol diet for 6 weeks underwent balloon injury to the abdominal aorta (AA) after week 3, and were then exposed to normoxia (n = 6), or 12 h daily of intermittent repetitive hypoxia (n = 6) or hyperoxia (n = 6) [12].
  • The abdominal aortas of five groups of rabbits were subjected to varying lengths of ischemia (0, 1, 2, 3, or 4 hours), removed, sectioned into transverse rings, and placed in tissue baths containing Krebs' buffer at 37 degrees C and aerated with 95% O2/5% CO2 [13].
  • In a rat model of thrombosis induced by ferric chloride application on the abdominal aorta, BM-573 significantly reduced the thrombus weight by 92.53, 80.20, 64.75, and 18.21% at doses of 5, 2, 0.5, and 0.2 mg/kg, respectively [14].
  • We previously reported that treatment with isosorbide dinitrate significantly reduced the moderate systolic hypertension and the increase in transparietal stress observed in the abdominal aorta of atheromatous animals [15].
  • Sudan IV was used to stain the lipid containing plaques of the aortic arch, thoracic and abdominal aorta and the surface area occupied by atheroma was assessed [16].

Biological context of Aorta, Abdominal


Anatomical context of Aorta, Abdominal


Associations of Aorta, Abdominal with chemical compounds

  • Vessel dimensions and characteristic responses to norepinephrine were measured in various arteries and veins of the rabbit made hypertensive by partial constriction of the upper abdominal aorta [26].
  • Methylene blue inhibited acetylcholine relaxation in both control and Brugia-infected abdominal aorta; however, relaxation in Brugia-infected aorta was significantly greater than control [27].
  • Mechanisms of transmural heparin transport in the rat abdominal aorta after local vascular delivery [28].
  • In anesthetized dogs, we recorded impulses from afferent fibers with endings in either the gastrocnemius or gracilis muscles and injected capsaicin (10-30 microgram/kg) into the abdominal aorta [29].
  • The pressure gradient between the ascending and abdominal aorta was not different between the cyclosporine-treated (49.6+/-6.1 mm Hg) and nontreatment groups (48.7+/-4.6 mm Hg) [30].

Gene context of Aorta, Abdominal


Analytical, diagnostic and therapeutic context of Aorta, Abdominal


  1. Increased nitric oxide synthase expression in arterial vessels of cirrhotic rats with ascites. Morales-Ruiz, M., Jiménez, W., Pérez-Sala, D., Ros, J., Leivas, A., Lamas, S., Rivera, F., Arroyo, V. Hepatology (1996) [Pubmed]
  2. Angiotensin II increases urokinase-type plasminogen activator expression and induces aneurysm in the abdominal aorta of apolipoprotein E-deficient mice. Wang, Y.X., Martin-McNulty, B., Freay, A.D., Sukovich, D.A., Halks-Miller, M., Li, W.W., Vergona, R., Sullivan, M.E., Morser, J., Dole, W.P., Deng, G.G. Am. J. Pathol. (2001) [Pubmed]
  3. Association of myocardial cell necrosis with experimental cardiac hypertrophy. Revis, N.W., Cameron, A.J. J. Pathol. (1979) [Pubmed]
  4. Origin of atherosclerosis in childhood and adolescence. McGill, H.C., McMahan, C.A., Herderick, E.E., Malcom, G.T., Tracy, R.E., Strong, J.P. Am. J. Clin. Nutr. (2000) [Pubmed]
  5. Simvastatin inhibits NOR-1 expression induced by hyperlipemia by interfering with CREB activation. Crespo, J., Martínez-González, J., Rius, J., Badimon, L. Cardiovasc. Res. (2005) [Pubmed]
  6. Circadian periodicity of cerebral blood flow revealed by laser-Doppler flowmetry in awake rats: relation to blood pressure and activity. Wauschkuhn, C.A., Witte, K., Gorbey, S., Lemmer, B., Schilling, L. Am. J. Physiol. Heart Circ. Physiol. (2005) [Pubmed]
  7. Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response. Udelsman, R., Blake, M.J., Stagg, C.A., Li, D.G., Putney, D.J., Holbrook, N.J. J. Clin. Invest. (1993) [Pubmed]
  8. N-arachidonoyl L-serine, an endocannabinoid-like brain constituent with vasodilatory properties. Milman, G., Maor, Y., Abu-Lafi, S., Horowitz, M., Gallily, R., Batkai, S., Mo, F.M., Offertaler, L., Pacher, P., Kunos, G., Mechoulam, R. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  9. Rapid noninvasive detection of experimental atherosclerotic lesions with novel 99mTc-labeled diadenosine tetraphosphates. Elmaleh, D.R., Narula, J., Babich, J.W., Petrov, A., Fischman, A.J., Khaw, B.A., Rapaport, E., Zamecnik, P.C. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  10. Inhalation of sidestream cigarette smoke accelerates development of arteriosclerotic plaques. Penn, A., Snyder, C.A. Circulation (1993) [Pubmed]
  11. The effect of porous infusion balloon-delivered angiopeptin on myointimal hyperplasia after balloon injury in the rabbit. Hong, M.K., Bhatti, T., Matthews, B.J., Stark, K.S., Cathapermal, S.S., Foegh, M.L., Ramwell, P.W., Kent, K.M. Circulation (1993) [Pubmed]
  12. Intimal thickening after arterial balloon injury is increased by intermittent repetitive hypoxia, but intermittent repetitive hyperoxia is not protective. Lau, A.K., Chaufour, X., McLachlan, C., Leichtweis, S.B., Celermajer, D.S., Sullivan, C., Stocker, R. Atherosclerosis (2006) [Pubmed]
  13. Effects of ischemia and hemoglobin on vascular function in isolated rabbit aortas. Ruiz, A.J., Chan, B.B., Meyerhoefer, T.A., Buck, D.R., Farley, P.C., Flanagan, T.L., Kron, I.L. J. Vasc. Surg. (1991) [Pubmed]
  14. Pharmacological characterization of N-tert-butyl-N'-[2-(4'-methylphenylamino)-5-nitrobenzenesulfonyl]urea (BM-573), a novel thromboxane A2 receptor antagonist and thromboxane synthase inhibitor in a rat model of arterial thrombosis and its effects on bleeding time. Dogné, J.M., Hanson, J., de Leval, X., Kolh, P., Tchana-Sato, V., de Leval, L., Rolin, S., Ghuysen, A., Segers, P., Lambermont, B., Masereel, B., Pirotte, B. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
  15. Medial elastic structure alterations in atherosclerotic arteries in minipigs: plaque proximity and arterial site specificity. Augier, T., Charpiot, P., Chareyre, C., Remusat, M., Rolland, P.H., Garçon, D. Matrix Biol. (1997) [Pubmed]
  16. Aminoguanidine has an anti-atherogenic effect in the cholesterol-fed rabbit. Panagiotopoulos, S., O'Brien, R.C., Bucala, R., Cooper, M.E., Jerums, G. Atherosclerosis (1998) [Pubmed]
  17. Influence of vascular smooth muscle heterogeneity on angiotensin converting enzyme activity in chicken embryonic aorta and in endothelial cells in culture. Topouzis, S., Catravas, J.D., Ryan, J.W., Rosenquist, T.H. Circ. Res. (1992) [Pubmed]
  18. Antibiotic prophylaxis in vascular surgery. Kaiser, A.B., Clayson, K.R., Mulherin, J.L., Roach, A.C., Allen, T.R., Edwards, W.H., Dale, W.A. Ann. Surg. (1978) [Pubmed]
  19. Hepatic lipase C-480T genotype-dependent benefit from long-term hormone replacement therapy for atherosclerosis progression in postmenopausal women. Fan, Y.M., Dastidar, P., Jokela, H., Punnonen, R., Lehtimäki, T. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
  20. Baroreflex sensitivity in conscious rats: the influence of recording site. Gardiner, S.M., Bennett, T. Cardiovasc. Res. (1986) [Pubmed]
  21. Aging-related induction of inducible nitric oxide synthase is vasculo-protective to the arterial media. Ferrini, M.G., Davila, H.H., Valente, E.G., Gonzalez-Cadavid, N.F., Rajfer, J. Cardiovasc. Res. (2004) [Pubmed]
  22. Vitamin E combined with selenium inhibits atherosclerosis in hypercholesterolemic rabbits independently of effects on plasma cholesterol concentrations. Schwenke, D.C., Behr, S.R. Circ. Res. (1998) [Pubmed]
  23. Direct effect of increased hemodynamic load on cardiac mass. Korecky, B., Masika, M. Circ. Res. (1991) [Pubmed]
  24. Effects of endothelin-1 on endothelial cells in the porcine coronary artery. Suzuki, S., Kajikuri, J., Suzuki, A., Itoh, T. Circ. Res. (1991) [Pubmed]
  25. Development of multiple necrotizing enteritis induced by a tumor necrosis factor-like cytokine from lipopolysaccharide-stimulated peritoneal macrophages in rats. Torimoto, K., Sato, N., Okubo, M., Yagihashi, A., Wada, Y., Hara, I., Hayasaka, H., Kikuchi, K. Am. J. Pathol. (1990) [Pubmed]
  26. Analysis of changes in reactivity of rabbit arteries and veins two weeks after induction of hypertension by coarctation of the abdominal aorta. Bevan, J.A., Bevan, R.D., Chang, P.C., Pegram, B.L., Purdy, R.E., Su, C. Circ. Res. (1975) [Pubmed]
  27. Depression of endothelium-dependent relaxation in aorta from rats with Brugia pahangi lymphatic filariasis. Kaiser, L., Tithof, P.K., Lamb, V.L., Williams, J.F. Circ. Res. (1991) [Pubmed]
  28. Mechanisms of transmural heparin transport in the rat abdominal aorta after local vascular delivery. Lovich, M.A., Edelman, E.R. Circ. Res. (1995) [Pubmed]
  29. Effects of capsaicin and bradykinin on afferent fibers with ending in skeletal muscle. Kaufman, M.P., Iwamoto, G.A., Longhurst, J.C., Mitchell, J.H. Circ. Res. (1982) [Pubmed]
  30. Cyclosporine attenuates pressure-overload hypertrophy in mice while enhancing susceptibility to decompensation and heart failure. Meguro, T., Hong, C., Asai, K., Takagi, G., McKinsey, T.A., Olson, E.N., Vatner, S.F. Circ. Res. (1999) [Pubmed]
  31. Ubiquitous elevation of matrix metalloproteinase-2 expression in the vasculature of patients with abdominal aneurysms. Goodall, S., Crowther, M., Hemingway, D.M., Bell, P.R., Thompson, M.M. Circulation (2001) [Pubmed]
  32. Molecular cloning, sequence, and expression of cynomolgus monkey cholesteryl ester transfer protein. Inverse correlation between hepatic cholesteryl ester transfer protein mRNA levels and plasma high density lipoprotein levels. Pape, M.E., Rehberg, E.F., Marotti, K.R., Melchior, G.W. Arterioscler. Thromb. (1991) [Pubmed]
  33. Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis. Mertens, A., Verhamme, P., Bielicki, J.K., Phillips, M.C., Quarck, R., Verreth, W., Stengel, D., Ninio, E., Navab, M., Mackness, B., Mackness, M., Holvoet, P. Circulation (2003) [Pubmed]
  34. Abdominal aortic aneurysms: distribution of elastin, collagen I and III, and intermediate filament proteins desmin and vimentin--a comparison of familial and nonfamilial aneurysms. Thornell, L.E., Norrgård, O., Eriksson, A., Vanderwee, M., Angqvist, K.A. Heart and vessels. (1986) [Pubmed]
  35. Identification of lectin-like substances recognizing galactosyl residues of glycoconjugates on the plasma membrane of marrow sinus endothelium. Kataoka, M., Tavassoli, M. Blood (1985) [Pubmed]
  36. The renin-angiotensin-aldosterone system in rabbits with congestive heart failure produced by aortic constriction. Morris, B.J., Davis, J.O., Zatzman, M.L., Williams, G.M. Circ. Res. (1977) [Pubmed]
  37. Bulbospinal serotonin pressor pathways and hypotensive action of methyldopa in the rat. Chalmers, J.P., Minson, J.B., Choy, V. Hypertension (1984) [Pubmed]
  38. Connection of smooth muscle cells to elastic lamellae in aorta of spontaneously hypertensive rats. Bezie, Y., Lacolley, P., Laurent, S., Gabella, G. Hypertension (1998) [Pubmed]
  39. Simple, rapid, and effective method of producing aortocaval shunts in the rat. Garcia, R., Diebold, S. Cardiovasc. Res. (1990) [Pubmed]
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