Gene Review:
SRA1 - steroid receptor RNA activator 1
Homo sapiens
Synonyms:
PP7684, SRA, SRAP, STRAA1, Steroid receptor RNA activator 1, ...
- Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation. Hubé, F., Velasco, G., Rollin, J., Furling, D., Francastel, C. Nucleic. Acids. Res. (2010)
- Increasing the relative expression of endogenous non-coding Steroid Receptor RNA Activator (SRA) in human breast cancer cells using modified oligonucleotides. Cooper, C., Guo, J., Yan, Y., Chooniedass-Kothari, S., Hube, F., Hamedani, M.K., Murphy, L.C., Myal, Y., Leygue, E. Nucleic. Acids. Res. (2009)
- Alternative splicing of the first intron of the steroid receptor RNA activator (SRA) participates in the generation of coding and noncoding RNA isoforms in breast cancer cell lines. Hube, F., Guo, J., Chooniedass-Kothari, S., Cooper, C., Hamedani, M.K., Dibrov, A.A., Blanchard, A.A., Wang, X., Deng, G., Myal, Y., Leygue, E. DNA Cell Biol. (2006)
- Expression and function of human steroid receptor RNA activator in prostate cancer cells: role of endogenous hSRA protein in androgen receptor-mediated transcription. Kurisu, T., Tanaka, T., Ishii, J., Matsumura, K., Sugimura, K., Nakatani, T., Kawashima, H. Prostate Cancer Prostatic Dis. (2006)
- Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo. Lanz, R.B., Chua, S.S., Barron, N., Söder, B.M., DeMayo, F., O'Malley, B.W. Mol. Cell. Biol. (2003)
- Expression analysis and prognostic significance of the SRA1 gene, in ovarian cancer. Leoutsakou, T., Talieri, M., Scorilas, A. Biochem. Biophys. Res. Commun. (2006)
- Macrophage scavenger receptor class A: A multifunctional receptor in atherosclerosis. de Winther, M.P., van Dijk, K.W., Havekes, L.M., Hofker, M.H. Arterioscler. Thromb. Vasc. Biol. (2000)
- When one is better than two: RNA with dual functions. Ulveling, D., Francastel, C., Hubé, F. Biochimie. (2010)
- A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Lanz, R.B., McKenna, N.J., Onate, S.A., Albrecht, U., Wong, J., Tsai, S.Y., Tsai, M.J., O'Malley, B.W. Cell (1999)
- SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. Hatchell, E.C., Colley, S.M., Beveridge, D.J., Epis, M.R., Stuart, L.M., Giles, K.M., Redfern, A.D., Miles, L.E., Barker, A., MacDonald, L.M., Arthur, P.G., Lui, J.C., Golding, J.L., McCulloch, R.K., Metcalf, C.B., Wilce, J.A., Wilce, M.C., Lanz, R.B., O'Malley, B.W., Leedman, P.J. Mol. Cell (2006)
- The steroid receptor RNA activator protein is expressed in breast tumor tissues. Chooniedass-Kothari, S., Hamedani, M.K., Troup, S., Hubé, F., Leygue, E. Int. J. Cancer (2006)
- Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation. Cavarretta, I.T., Mukopadhyay, R., Lonard, D.M., Cowsert, L.M., Bennett, C.F., O'Malley, B.W., Smith, C.L. Mol. Endocrinol. (2002)
- Ligand-independent coactivation of ERalpha AF-1 by steroid receptor RNA activator (SRA) via MAPK activation. Deblois, G., Giguère, V. J. Steroid Biochem. Mol. Biol. (2003)
- Biological characterization of multidrug-resistant human colon carcinoma sublines induced/selected by two methods. Yang, L.Y., Trujillo, J.M. Cancer Res. (1990)
- Mimicking phosphorylation at Ser-48 strongly reduces surface expression of human macrophage scavenger receptor class A: implications on cell motility. Heider, H., Wintergerst, E.S. FEBS Lett. (2001)
- A novel steroid receptor co-activator protein (SRAP) as an alternative form of steroid receptor RNA-activator gene: expression in prostate cancer cells and enhancement of androgen receptor activity. Kawashima, H., Takano, H., Sugita, S., Takahara, Y., Sugimura, K., Nakatani, T. Biochem. J. (2003)
- SRA coactivation of estrogen receptor-alpha is phosphorylation-independent, and enhances 4-hydroxytamoxifen agonist activity. Coleman, K.M., Lam, V., Jaber, B.M., Lanz, R.B., Smith, C.L. Biochem. Biophys. Res. Commun. (2004)
- Altered expression of estrogen receptor coregulators during human breast tumorigenesis. Murphy, L.C., Simon, S.L., Parkes, A., Leygue, E., Dotzlaw, H., Snell, L., Troup, S., Adeyinka, A., Watson, P.H. Cancer Res. (2000)
- Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA). Lanz, R.B., Razani, B., Goldberg, A.D., O'Malley, B.W. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Pseudo-steroid resistant asthma. Thomas, P.S., Geddes, D.M., Barnes, P.J. Thorax (1999)