Gene Review:
LEFTY1 - left-right determination factor 1
Homo sapiens
Synonyms:
LEFTB, LEFTYB, Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, ...
- Tet responsive and adenovirus based constructs for regulated in vivo expression of Lefty. Mikhailik, A., Tang, M., Hearing, P., Ravishankar, V., Tabibzadeh, S. Front. Biosci. (2006)
- Role of EBAF/Lefty in implantation and uterine bleeding. Tabibzadeh, S. Ernst Schering Res. Found. Workshop (2005)
- Nodal signaling in vertebrate development. Schier, A.F. Annu. Rev. Cell Dev. Biol. (2003)
- Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development. Kosaki, K., Bassi, M.T., Kosaki, R., Lewin, M., Belmont, J., Schauer, G., Casey, B. Am. J. Hum. Genet. (1999)
- Klf4 cooperates with oct3/4 and sox2 to activate the lefty1 core promoter in embryonic stem cells. Nakatake, Y., Fukui, N., Iwamatsu, Y., Masui, S., Takahashi, K., Yagi, R., Yagi, K., Miyazaki, J., Matoba, R., Ko, M.S., Niwa, H. Mol. Cell. Biol. (2006)
- Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning. Mesnard, D., Guzman-Ayala, M., Constam, D.B. Development (2006)
- Distinct transcriptional regulation and phylogenetic divergence of human LEFTY genes. Yashiro, K., Saijoh, Y., Sakuma, R., Tada, M., Tomita, N., Amano, K., Matsuda, Y., Monden, M., Okada, S., Hamada, H. Genes Cells (2000)
- Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor. Ulloa, L., Tabibzadeh, S. J. Biol. Chem. (2001)
- Nodal signaling: CrypticLefty mechanism of antagonism decoded. Branford, W.W., Yost, H.J. Curr. Biol. (2004)
- Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3. Besser, D. J. Biol. Chem. (2004)
- RTK and TGF-beta signaling pathways genes in the sea urchin genome. Lapraz, F., R??ttinger, E., Duboc, V., Range, R., Duloquin, L., Walton, K., Wu, S.Y., Bradham, C., Loza, M.A., Hibino, T., Wilson, K., Poustka, A., McClay, D., Angerer, L., Gache, C., Lepage, T. Dev. Biol. (2006)
- Induction of initial cardiomyocyte alpha-actin--smooth muscle alpha-actin--in cultured avian pregastrula epiblast: a role for nodal and BMP antagonist. Matsui, H., Ikeda, K., Nakatani, K., Sakabe, M., Yamagishi, T., Nakanishi, T., Nakajima, Y. Dev. Dyn. (2005)
- Homeostasis of extracellular matrix by TGF-beta and lefty. Tabibzadeh, S. Front. Biosci. (2002)
- Lefty at the crossroads of "stemness" and differentiative events. Tabibzadeh, S., Hemmati-Brivanlou, A. Stem Cells (2006)