Gene Review:
PTP4A3 - protein tyrosine phosphatase type IVA,...
Homo sapiens
Synonyms:
PRL-3, PRL-R, PRL3, Protein tyrosine phosphatase type IVA 3, Protein-tyrosine phosphatase 4a3, ...
- Structural insights into molecular function of the metastasis-associated phosphatase PRL-3. Kozlov, G., Cheng, J., Ziomek, E., Banville, D., Gehring, K., Ekiel, I. J. Biol. Chem. (2004)
- Generation of PRL-3- and PRL-1-specific monoclonal antibodies as potential diagnostic markers for cancer metastases. Li, J., Guo, K., Koh, V.W., Tang, J.P., Gan, B.Q., Shi, H., Li, H.X., Zeng, Q. Clin. Cancer Res. (2005)
- PRL-3 phosphatase is implicated in ovarian cancer growth. Polato, F., Codegoni, A., Fruscio, R., Perego, P., Mangioni, C., Saha, S., Bardelli, A., Broggini, M. Clin. Cancer Res. (2005)
- Translational control of C-terminal Src kinase (Csk) expression by PRL3 phosphatase. Liang, F., Luo, Y., Dong, Y., Walls, C.D., Liang, J., Jiang, H.Y., Sanford, J.R., Wek, R.C., Zhang, Z.Y. J. Biol. Chem. (2008)
- A phosphatase associated with metastasis of colorectal cancer. Saha, S., Bardelli, A., Buckhaults, P., Velculescu, V.E., Rago, C., St Croix, B., Romans, K.E., Choti, M.A., Lengauer, C., Kinzler, K.W., Vogelstein, B. Science (2001)
- PRL-3 Initiates Tumor Angiogenesis by Recruiting Endothelial Cells In vitro and In vivo. Guo, K., Li, J., Wang, H., Osato, M., Tang, J.P., Quah, S.Y., Gan, B.Q., Zeng, Q. Cancer Res. (2006)
- DNA copy number changes at 8q11-24 in metastasized colorectal cancer. Buffart, T.E., Coffa, J., Hermsen, M.A., Carvalho, B., van der Sijp, J.R., Ylstra, B., Pals, G., Schouten, J.P., Meijer, G.A. Cellular oncology : the official journal of the International Society for Cellular Oncology. (2005)
- A novel estradiol/estrogen receptor alpha-dependent transcriptional mechanism controls expression of the human prolactin receptor. Dong, J., Tsai-Morris, C.H., Dufau, M.L. J. Biol. Chem. (2006)
- PRL-3 expression in metastatic cancers. Bardelli, A., Saha, S., Sager, J.A., Romans, K.E., Xin, B., Markowitz, S.D., Lengauer, C., Velculescu, V.E., Kinzler, K.W., Vogelstein, B. Clin. Cancer Res. (2003)
- High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases. Kato, H., Semba, S., Miskad, U.A., Seo, Y., Kasuga, M., Yokozaki, H. Clin. Cancer Res. (2004)
- Trimeric structure of PRL-1 phosphatase reveals an active enzyme conformation and regulation mechanisms. Jeong, D.G., Kim, S.J., Kim, J.H., Son, J.H., Park, M.R., Lim, S.M., Yoon, T.S., Ryu, S.E. J. Mol. Biol. (2005)
- Expression and prognostic impact of the protein tyrosine phosphatases PRL-1, PRL-2, and PRL-3 in breast cancer. Radke, I., Götte, M., Kersting, C., Mattsson, B., Kiesel, L., Wülfing, P. Br. J. Cancer (2006)
- Protein tyrosine phosphatase PRL-3 in malignant cells and endothelial cells: expression and function. Rouleau, C., Roy, A., St Martin, T., Dufault, M.R., Boutin, P., Liu, D., Zhang, M., Puorro-Radzwill, K., Rulli, L., Reczek, D., Bagley, R., Byrne, A., Weber, W., Roberts, B., Klinger, K., Brondyk, W., Nacht, M., Madden, S., Burrier, R., Shankara, S., Teicher, B.A. Mol. Cancer Ther. (2006)
- Structure of human PRL-3, the phosphatase associated with cancer metastasis. Kim, K.A., Song, J.S., Jee, J., Sheen, M.R., Lee, C., Lee, T.G., Ro, S., Cho, J.M., Lee, W., Yamazaki, T., Jeon, Y.H., Cheong, C. FEBS Lett. (2004)
- Identification of integrin alpha1 as an interacting protein of protein tyrosine phosphatase PRL-3. Peng, L., Jin, G., Wang, L., Guo, J., Meng, L., Shou, C. Biochem. Biophys. Res. Commun. (2006)
- Role of PRL-3, a human muscle-specific tyrosine phosphatase, in angiotensin-II signaling. Matter, W.F., Estridge, T., Zhang, C., Belagaje, R., Stancato, L., Dixon, J., Johnson, B., Bloem, L., Pickard, T., Donaghue, M., Acton, S., Jeyaseelan, R., Kadambi, V., Vlahos, C.J. Biochem. Biophys. Res. Commun. (2001)