Gene Review:
POLI - polymerase (DNA directed) iota
Homo sapiens
Synonyms:
DNA polymerase iota, Eta2, RAD30 homolog B, RAD30B, RAD3OB
- Association of amino acid substitution polymorphisms in DNA repair genes TP53, POLI, REV1 and LIG4 with lung cancer risk. Sakiyama, T., Kohno, T., Mimaki, S., Ohta, T., Yanagitani, N., Sobue, T., Kunitoh, H., Saito, R., Shimizu, K., Hirama, C., Kimura, J., Maeno, G., Hirose, H., Eguchi, T., Saito, D., Ohki, M., Yokota, J. Int. J. Cancer (2005)
- Genome sequence and splice site analysis of low-fidelity DNA polymerases H and I involved in replication of damaged DNA. Cleaver, J.E., Collins, C., Ellis, J., Volik, S. Genomics (2003)
- Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota. Faili, A., Aoufouchi, S., Flatter, E., Guéranger, Q., Reynaud, C.A., Weill, J.C. Nature (2002)
- Altered DNA polymerase iota expression in breast cancer cells leads to a reduction in DNA replication fidelity and a higher rate of mutagenesis. Yang, J., Chen, Z., Liu, Y., Hickey, R.J., Malkas, L.H. Cancer Res. (2004)
- Polyneuropathy, ophthalmoplegia, leukoencephalopathy, and intestinal pseudo-obstruction: POLIP syndrome. Simon, L.T., Horoupian, D.S., Dorfman, L.J., Marks, M., Herrick, M.K., Wasserstein, P., Smith, M.E. Ann. Neurol. (1990)
- Eukaryotic polymerases iota and zeta act sequentially to bypass DNA lesions. Johnson, R.E., Washington, M.T., Haracska, L., Prakash, S., Prakash, L. Nature (2000)
- Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota. Johnson, R.E., Prakash, L., Prakash, S. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Targeting of human DNA polymerase iota to the replication machinery via interaction with PCNA. Haracska, L., Johnson, R.E., Unk, I., Phillips, B.B., Hurwitz, J., Prakash, L., Prakash, S. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype. Smit, L.A., Bende, R.J., Aten, J., Guikema, J.E., Aarts, W.M., van Noesel, C.J. Cancer Res. (2003)
- Uterine changes during tamoxifen therapy. Rullo, S., Tagliaferri, T., Bandiera, F., Fiorelli, C., Felici, A., Piccioni, M.G., Framarino dei Malatesta, M.L. Clinical and experimental obstetrics & gynecology. (1993)
- Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta. McDonald, J.P., Rapić-Otrin, V., Epstein, J.A., Broughton, B.C., Wang, X., Lehmann, A.R., Wolgemuth, D.J., Woodgate, R. Genomics (1999)
- Replication past a trans-4-hydroxynonenal minor-groove adduct by the sequential action of human DNA polymerases iota and kappa. Wolfle, W.T., Johnson, R.E., Minko, I.G., Lloyd, R.S., Prakash, S., Prakash, L. Mol. Cell. Biol. (2006)
- Localization of the deoxyribose phosphate lyase active site in human DNA polymerase iota by controlled proteolysis. Prasad, R., Bebenek, K., Hou, E., Shock, D.D., Beard, W.A., Woodgate, R., Kunkel, T.A., Wilson, S.H. J. Biol. Chem. (2003)
- A false note of DNA polymerase iota in the choir of genome caretakers in mammals. Gening, L.V., Makarova, A.V., Malashenko, A.M., Tarantul, V.Z. Biochemistry Mosc. (2006)
- Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota. Frank, E.G., Sayer, J.M., Kroth, H., Ohashi, E., Ohmori, H., Jerina, D.M., Woodgate, R. Nucleic Acids Res. (2002)
- Effects of various finishing systems on the surface roughness and staining susceptibility of packable composite resins. Reis, A.F., Giannini, M., Lovadino, J.R., Ambrosano, G.M. Dental materials : official publication of the Academy of Dental Materials. (2003)
- Digestive smooth muscle mitochondrial myopathy in patients with mitochondrial-neuro-gastro-intestinal encephalomyopathy (MNGIE). Blondon, H., Polivka, M., Joly, F., Flourie, B., Mikol, J., Messing, B. Gastroenterol. Clin. Biol. (2005)
- An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Nair, D.T., Johnson, R.E., Prakash, L., Prakash, S., Aggarwal, A.K. Structure (2006)
- Impaired glutathione redox status is associated with decreased survival in two organophosphate-poisoned marine bivalves. Peña-Llopis, S., Ferrando, M.D., Peña, J.B. Chemosphere (2002)
- Proliferating cell nuclear antigen-dependent coordination of the biological functions of human DNA polymerase iota. Vidal, A.E., Kannouche, P., Podust, V.N., Yang, W., Lehmann, A.R., Woodgate, R. J. Biol. Chem. (2004)
- poliota, a remarkably error-prone human DNA polymerase. Tissier, A., McDonald, J.P., Frank, E.G., Woodgate, R. Genes Dev. (2000)
- 129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation. McDonald, J.P., Frank, E.G., Plosky, B.S., Rogozin, I.B., Masutani, C., Hanaoka, F., Woodgate, R., Gearhart, P.J. J. Exp. Med. (2003)
- Improving government health services through contract management: a case from Cambodia. Soeters, R., Griffiths, F. Health policy and planning. (2003)