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Gene Review

Ofa  -  oncofetal antigen

Mus musculus

Synonyms: 59kDa
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Disease relevance of Ofa


High impact information on Ofa


Chemical compound and disease context of Ofa


Biological context of Ofa


Anatomical context of Ofa


Associations of Ofa with chemical compounds


Analytical, diagnostic and therapeutic context of Ofa


  1. Expression of 44-kilodalton oncofetal antigen as a premalignancy marker in X irradiation-induced murine T-cell lymphoma. Rohrer, S.D., Sarli, R.N., Barsoum, A.L., Hester, R.B., Coggin, J.H. J. Natl. Cancer Inst. (1992) [Pubmed]
  2. Induction of cytotoxic T-cell responses against the oncofetal antigen-immature laminin receptor for the treatment of hematologic malignancies. Siegel, S., Wagner, A., Kabelitz, D., Marget, M., Coggin, J., Barsoum, A., Rohrer, J., Schmitz, N., Zeis, M. Blood (2003) [Pubmed]
  3. Embryonic stem cell-derived dendritic cells expressing glypican-3, a recently identified oncofetal antigen, induce protective immunity against highly metastatic mouse melanoma, B16-F10. Motomura, Y., Senju, S., Nakatsura, T., Matsuyoshi, H., Hirata, S., Monji, M., Komori, H., Fukuma, D., Baba, H., Nishimura, Y. Cancer Res. (2006) [Pubmed]
  4. Radiation-induced lymphoblastic lymphomas/leukemias and sarcomas of mice express conserved, immunogenic 44-kilodalton oncofetal antigen. Coggin, J.H., Rohrer, S.D., Leinbach, E.D., Hester, R.B., Liu, P.I., Heath, L.S. Am. J. Pathol. (1988) [Pubmed]
  5. Subsets of oncofetal antigen-induced T-cells: ability to mediate antitumor immune response. Gautam, S., Deodhar, S.D. J. Natl. Cancer Inst. (1983) [Pubmed]
  6. Monoclonal antiidiotypic antibodies related to a murine oncofetal bladder tumor antigen induce specific cell-mediated tumor immunity. Lee, V.K., Harriott, T.G., Kuchroo, V.K., Halliday, W.J., Hellström, I., Hellström, K.E. Proc. Natl. Acad. Sci. U.S.A. (1985) [Pubmed]
  7. Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody B72.3. Thor, A., Ohuchi, N., Szpak, C.A., Johnston, W.W., Schlom, J. Cancer Res. (1986) [Pubmed]
  8. Biosynthesis of N-glycolyneuraminic acid. The primary site of hydroxylation of N-acetylneuraminic acid is the cytosolic sugar nucleotide pool. Muchmore, E.A., Milewski, M., Varki, A., Diaz, S. J. Biol. Chem. (1989) [Pubmed]
  9. Purification and partial characterization of 200 kDa oncofetal antigen from radiation induced murine lymphocytic lymphoma. Barsoum, A.L., Coggin, J.H. Int. J. Biochem. (1993) [Pubmed]
  10. Helicobacter pylori expresses a complex surface carbohydrate, Lewis X. Sherburne, R., Taylor, D.E. Infect. Immun. (1995) [Pubmed]
  11. 44-kd oncofetal transplantation antigen in rodent and human fetal cells. Implications of recrudescence in human and rodent cancers. Coggin, J.H., Rohrer, S.D., Hester, R.D., Barsoum, A.L., Rashid, H.U., Gussack, G.S. Arch. Otolaryngol. Head Neck Surg. (1993) [Pubmed]
  12. Identification of oncofetal antigen/immature laminin receptor protein epitopes that activate BALB/c mouse OFA/iLRP-specific effector and regulatory T cell clones. Rohrer, J.W., Barsoum, A.L., Coggin, J.H. J. Immunol. (2006) [Pubmed]
  13. Isolation and partial characterization of a soluble oncofetal antigen from murine and human amniotic fluids. Barsoum, A.L., Coggin, J.H. Int. J. Cancer (1991) [Pubmed]
  14. Characterization and distribution of an oncofetal antigen (M2A antigen) expressed on testicular germ cell tumours. Marks, A., Sutherland, D.R., Bailey, D., Iglesias, J., Law, J., Lei, M., Yeger, H., Banerjee, D., Baumal, R. Br. J. Cancer (1999) [Pubmed]
  15. Immunohistochemical study of a newly defined oncofetal antigen (HGR-Ag) in tumors of the central nervous system. Hashimoto, H., Sakaki, T., Tsunoda, S., Morimoto, T., Hoshida, T., Hiasa, Y., Konishi, N. Neurol. Med. Chir. (Tokyo) (1992) [Pubmed]
  16. Immunogenicity of a soluble partially purified oncofetal antigen from murine fibrosarcoma in syngeneic mice. Barsoum, A.L., Coggin, J.H. Journal of biological response modifiers. (1989) [Pubmed]
  17. Usefulness of the novel oncofetal antigen glypican-3 for diagnosis of hepatocellular carcinoma and melanoma. Nakatsura, T., Nishimura, Y. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. (2005) [Pubmed]
  18. Human chorionic gonadotropin as a target for cancer vaccines. Triozzi, P.L., Stevens, V.C. Oncol. Rep. (1999) [Pubmed]
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