Gene Review:
Pax8 - paired box 8
Mus musculus
Synonyms:
Paired box protein Pax-8, Pax-8
- Expression of pituitary hormones in the Pax8-/- mouse model of congenital hypothyroidism. Friedrichsen, S., Christ, S., Heuer, H., Schäfer, M.K., Parlow, A.F., Visser, T.J., Bauer, K. Endocrinology (2004)
- Athyroid Pax8-/- mice cannot be rescued by the inactivation of thyroid hormone receptor alpha1. Mittag, J., Friedrichsen, S., Heuer, H., Polsfuss, S., Visser, T.J., Bauer, K. Endocrinology (2005)
- Hearing loss in athyroid pax8 knockout mice and effects of thyroxine substitution. Christ, S., Biebel, U.W., Hoidis, S., Friedrichsen, S., Bauer, K., Smolders, J.W. Audiol. Neurootol. (2004)
- Congenital hypothyroid female pax8-deficient mice are infertile despite thyroid hormone replacement therapy. Mittag, J., Winterhager, E., Bauer, K., Grümmer, R. Endocrinology (2007)
- Binding and activation of the promoter for the neural cell adhesion molecule by Pax-8. Holst, B.D., Goomer, R.S., Wood, I.C., Edelman, G.M., Jones, F.S. J. Biol. Chem. (1994)
- Follicular cells of the thyroid gland require Pax8 gene function. Mansouri, A., Chowdhury, K., Gruss, P. Nat. Genet. (1998)
- Nephric lineage specification by Pax2 and Pax8. Bouchard, M., Souabni, A., Mandler, M., Neubüser, A., Busslinger, M. Genes Dev. (2002)
- Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8. Kozmik, Z., Czerny, T., Busslinger, M. EMBO J. (1997)
- Male congenital hypothyroid Pax8-/- mice are infertile despite adequate treatment with thyroid hormone. Wistuba, J., Mittag, J., Luetjens, C.M., Cooper, T.G., Yeung, C.H., Nieschlag, E., Bauer, K. J. Endocrinol. (2007)
- Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Plachov, D., Chowdhury, K., Walther, C., Simon, D., Guenet, J.L., Gruss, P. Development (1990)
- Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. Narlis, M., Grote, D., Gaitan, Y., Boualia, S.K., Bouchard, M. J. Am. Soc. Nephrol. (2007)
- Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene. Flamant, F., Poguet, A.L., Plateroti, M., Chassande, O., Gauthier, K., Streichenberger, N., Mansouri, A., Samarut, J. Mol. Endocrinol. (2002)
- Tissue-specific expression of cre recombinase from the Pax8 locus. Bouchard, M., Souabni, A., Busslinger, M. Genesis (2004)
- Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage. Clarke, J.C., Patel, S.R., Raymond, R.M., Andrew, S., Robinson, B.G., Dressler, G.R., Brophy, P.D. Hum. Mol. Genet. (2006)
- Thyroid hormone regulates hepatic triglyceride mobilization and apolipoprotein B messenger ribonucleic Acid editing in a murine model of congenital hypothyroidism. Mukhopadhyay, D., Plateroti, M., Anant, S., Nassir, F., Samarut, J., Davidson, N.O. Endocrinology (2003)
- Pax 8 expression in primary cultured dog thyrocyte is increased by cyclic AMP. Van Renterghem, P., Vassart, G., Christophe, D. Biochim. Biophys. Acta (1996)
- An integrated regulatory network controlling survival and migration in thyroid organogenesis. Parlato, R., Rosica, A., Rodriguez-Mallon, A., Affuso, A., Postiglione, M.P., Arra, C., Mansouri, A., Kimura, S., Di Lauro, R., De Felice, M. Dev. Biol. (2004)
- Thyroglobulin increases cell proliferation and suppresses Pax-8 in mesangial cells. Sellitti, D.F., Suzuki, K., Doi, S.Q., LaGranha, C., Machado, M., Matos, T., Kohn, L.D. Biochem. Biophys. Res. Commun. (2001)
- Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function. Pfeffer, P.L., Gerster, T., Lun, K., Brand, M., Busslinger, M. Development (1998)
- Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates. Holland, L.Z., Rached, L.A., Tamme, R., Holland, N.D., Kortschak, D., Inoko, H., Shiina, T., Burgtorf, C., Lardelli, M. Dev. Biol. (2001)
- Urogenital syndrome (us): a developmental mutation on chromosome 2 of the mouse. Lane, P.W., Birkenmeier, C.S. Mamm. Genome (1993)
- Thyroid hormone deficiency affects postnatal spiking activity and expression of Ca2+ and K+ channels in rodent inner hair cells. Brandt, N., Kuhn, S., Münkner, S., Braig, C., Winter, H., Blin, N., Vonthein, R., Knipper, M., Engel, J. J. Neurosci. (2007)