Gene Review:
Smarca4 - SWI/SNF related, matrix associated, actin...
Mus musculus
Synonyms:
ATP-dependent helicase SMARCA4, BAF190A, BRG1-associated factor 190A, Baf190a, Brg1, ...
- A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development. Bultman, S.J., Gebuhr, T.C., Magnuson, T. Genes Dev. (2005)
- SWI/SNF chromatin-remodeling factors induce changes in DNA methylation to promote transcriptional activation. Banine, F., Bartlett, C., Gunawardena, R., Muchardt, C., Yaniv, M., Knudsen, E.S., Weissman, B.E., Sherman, L.S. Cancer Res. (2005)
- Maternal BRG1 regulates zygotic genome activation in the mouse. Bultman, S.J., Gebuhr, T.C., Pan, H., Svoboda, P., Schultz, R.M., Magnuson, T. Genes Dev. (2006)
- A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Bultman, S., Gebuhr, T., Yee, D., La Mantia, C., Nicholson, J., Gilliam, A., Randazzo, F., Metzger, D., Chambon, P., Crabtree, G., Magnuson, T. Mol. Cell (2000)
- Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha). Reyes, J.C., Barra, J., Muchardt, C., Camus, A., Babinet, C., Yaniv, M. EMBO J. (1998)
- Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation. Indra, A.K., Dupé, V., Bornert, J.M., Messaddeq, N., Yaniv, M., Mark, M., Chambon, P., Metzger, D. Development (2005)
- SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation. Young, D.W., Pratap, J., Javed, A., Weiner, B., Ohkawa, Y., van Wijnen, A., Montecino, M., Stein, G.S., Stein, J.L., Imbalzano, A.N., Lian, J.B. J. Cell. Biochem. (2005)
- The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development. Gebuhr, T.C., Kovalev, G.I., Bultman, S., Godfrey, V., Su, L., Magnuson, T. J. Exp. Med. (2003)
- The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD. Seo, S., Richardson, G.A., Kroll, K.L. Development (2005)
- SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells. Sumi-Ichinose, C., Ichinose, H., Metzger, D., Chambon, P. Mol. Cell. Biol. (1997)
- Formation of higher-order secondary and tertiary chromatin structures by genomic mouse mammary tumor virus promoters. Georgel, P.T., Fletcher, T.M., Hager, G.L., Hansen, J.C. Genes Dev. (2003)
- T helper type 1-specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-gamma promoter are Stat4 dependent. Zhang, F., Boothby, M. J. Exp. Med. (2006)
- Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1. Ohkawa, Y., Marfella, C.G., Imbalzano, A.N. EMBO J. (2006)
- Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes. Vradii, D., Wagner, S., Doan, D.N., Nickerson, J.A., Montecino, M., Lian, J.B., Stein, J.L., van Wijnen, A.J., Imbalzano, A.N., Stein, G.S. J. Cell. Physiol. (2006)