Gene Review:
Vpreb2 - pre-B lymphocyte gene 2
Mus musculus
Synonyms:
CD179b, Immunoglobulin omega chain, Protein VPreB2, VpreB1, Vpreb-2
Shimizu,
Mundt,
Licence,
Melchers,
Mårtensson,
Rolink,
Schaniel,
Busslinger,
Nutt,
Melchers,
Rolink,
Nutt,
Melchers,
Busslinger,
- The expression of the mouse VpreB/lambda 5 locus in transformed cell lines and tumors of the B lineage differentiation pathway. Kudo, A., Thalmann, P., Sakaguchi, N., Davidson, W.F., Pierce, J.H., Kearney, J.F., Reth, M., Rolink, A., Melchers, F. Int. Immunol. (1992)
- Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors. Rolink, A.G., Nutt, S.L., Melchers, F., Busslinger, M. Nature (1999)
- Loss of precursor B cell expansion but not allelic exclusion in VpreB1/VpreB2 double-deficient mice. Mundt, C., Licence, S., Shimizu, T., Melchers, F., Mårtensson, I.L. J. Exp. Med. (2001)
- The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver. Li, Y.S., Hayakawa, K., Hardy, R.R. J. Exp. Med. (1993)
- The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription. Parker, M.J., Licence, S., Erlandsson, L., Galler, G.R., Chakalova, L., Osborne, C.S., Morgan, G., Fraser, P., Jumaa, H., Winkler, T.H., Skok, J., Mårtensson, I.L. EMBO J. (2005)
- A second gene, VpreB in the lambda 5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes. Kudo, A., Melchers, F. EMBO J. (1987)
- Identification of a tissue- and differentiation stage-specific enhancer of the VpreB1 gene. Persson, C., Mårtensson, A., Mårtensson, I.L. Eur. J. Immunol. (1998)
- Pre-B lymphocyte-specific transcriptional control of the mouse VpreB gene. Okabe, T., Bauer, S.R., Kudo, A. Eur. J. Immunol. (1992)
- The murine VpreB1 and VpreB2 genes both encode a protein of the surrogate light chain and are co-expressed during B cell development. Dul, J.L., Argon, Y., Winkler, T., ten Boekel, E., Melchers, F., Mårtensson, I.L. Eur. J. Immunol. (1996)
- The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain. Karasuyama, H., Kudo, A., Melchers, F. J. Exp. Med. (1990)
- The reduced expression of surrogate light chains in B cell precursors from senescent BALB/c mice is associated with decreased E2A proteins. Sherwood, E.M., Xu, W., King, A.M., Blomberg, B.B., Riley, R.L. Mech. Ageing Dev. (2000)
- A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines. Karasuyama, H., Rolink, A., Melchers, F. J. Exp. Med. (1993)
- Pax-5 is identical to EBB-1/KLP and binds to the VpreB and lambda5 promoters as well as the KI and KII sites upstream of the Jkappa genes. Tian, J., Okabe, T., Miyazaki, T., Takeshita, S., Kudo, A. Eur. J. Immunol. (1997)
- Identification and localization of a developmental stage-specific promoter activity from the murine lambda 5 gene. Yang, J., Glozak, M.A., Blomberg, B.B. J. Immunol. (1995)
- VpreB1/VpreB2/lambda 5 triple-deficient mice show impaired B cell development but functional allelic exclusion of the IgH locus. Shimizu, T., Mundt, C., Licence, S., Melchers, F., Mårtensson, I.L. J. Immunol. (2002)
- A novel gene product associated with mu chains in immature B cells. Shirasawa, T., Ohnishi, K., Hagiwara, S., Shigemoto, K., Takebe, Y., Rajewsky, K., Takemori, T. EMBO J. (1993)
- A pre-B- and B cell-specific DNA-binding protein, EBB-1, which binds to the promoter of the VpreB1 gene. Okabe, T., Watanabe, T., Kudo, A. Eur. J. Immunol. (1992)
- Fidelity and infidelity in commitment to B-lymphocyte lineage development. Rolink, A.G., Schaniel, C., Busslinger, M., Nutt, S.L., Melchers, F. Immunol. Rev. (2000)
- GL7 defines the cycling stage of pre-B cells in murine bone marrow. Murasawa, M., Okada, S., Obata, S., Hatano, M., Moriya, H., Tokuhisa, T. Eur. J. Immunol. (2002)
- The B cell receptor, but not the pre-B cell receptor, mediates arrest of B cell differentiation. Ceredig, R., Rolink, A.G., Melchers, F., Andersson, J. Eur. J. Immunol. (2000)