Gene Review:
Slc9a2 - solute carrier family 9 (sodium/hydrogen...
Mus musculus
Synonyms:
2210416H12Rik, 4932415O19Rik, AV333884, NHE2
- Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger. Gawenis, L.R., Greeb, J.M., Prasad, V., Grisham, C., Sanford, L.P., Doetschman, T., Andringa, A., Miller, M.L., Shull, G.E. J. Biol. Chem. (2005)
- Variant form of diffuse corporal gastritis in NHE2 knockout mice. Boivin, G.P., Schultheis, P.J., Shull, G.E., Stemmermann, G.N. Comp. Med. (2000)
- Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Schultheis, P.J., Clarke, L.L., Meneton, P., Miller, M.L., Soleimani, M., Gawenis, L.R., Riddle, T.M., Duffy, J.J., Doetschman, T., Wang, T., Giebisch, G., Aronson, P.S., Lorenz, J.N., Shull, G.E. Nat. Genet. (1998)
- Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct. Lee, M.G., Ahn, W., Choi, J.Y., Luo, X., Seo, J.T., Schultheis, P.J., Shull, G.E., Kim, K.H., Muallem, S. J. Clin. Invest. (2000)
- Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion. Schultheis, P.J., Clarke, L.L., Meneton, P., Harline, M., Boivin, G.P., Stemmermann, G., Duffy, J.J., Doetschman, T., Miller, M.L., Shull, G.E. J. Clin. Invest. (1998)
- Defective fluid secretion and NaCl absorption in the parotid glands of Na+/H+ exchanger-deficient mice. Park, K., Evans, R.L., Watson, G.E., Nehrke, K., Richardson, L., Bell, S.M., Schultheis, P.J., Hand, A.R., Shull, G.E., Melvin, J.E. J. Biol. Chem. (2001)
- Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2. Ledoussal, C., Lorenz, J.N., Nieman, M.L., Soleimani, M., Schultheis, P.J., Shull, G.E. Am. J. Physiol. Renal Physiol. (2001)
- The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation. Bachmann, O., Riederer, B., Rossmann, H., Groos, S., Schultheis, P.J., Shull, G.E., Gregor, M., Manns, M.P., Seidler, U. Am. J. Physiol. Gastrointest. Liver Physiol. (2004)
- Differential expression and regulation of Na(+)/H(+) exchanger isoforms in rabbit parietal and mucous cells. Rossmann, H., Sonnentag, T., Heinzmann, A., Seidler, B., Bachmann, O., Vieillard-Baron, D., Gregor, M., Seidler, U. Am. J. Physiol. Gastrointest. Liver Physiol. (2001)
- Na+/H+ exchanger isoform 2 (NHE2) is expressed in the apical membrane of the medullary thick ascending limb. Sun, A.M., Liu, Y., Dworkin, L.D., Tse, C.M., Donowitz, M., Yip, K.P. J. Membr. Biol. (1997)
- Targeted disruption of the Nhe1 gene prevents muscarinic agonist-induced up-regulation of Na(+)/H(+) exchange in mouse parotid acinar cells. Evans, R.L., Bell, S.M., Schultheis, P.J., Shull, G.E., Melvin, J.E. J. Biol. Chem. (1999)
- NHE1, NHE2, and NHE3 contribute to regulation of intracellular pH in murine duodenal epithelial cells. Praetorius, J., Andreasen, D., Jensen, B.L., Ainsworth, M.A., Friis, U.G., Johansen, T. Am. J. Physiol. Gastrointest. Liver Physiol. (2000)
- Na+/H+ exchanger activity and phosphorylation in temperature-sensitive immortalized proximal tubule cell lines derived from the spontaneously hypertensive rat. Ng, L.L., Jennings, S., Davies, J.E., Quinn, P.A. Clin. Sci. (2000)
- Functional linkage of H+/peptide transporter PEPT2 and Na+/H+ exchanger in primary cultures of astrocytes from mouse cerebral cortex. Wada, M., Miyakawa, S., Shimada, A., Okada, N., Yamamoto, A., Fujita, T. Brain Res. (2005)
- Expression, immunolocalization, and functional activity of Na+/H+ exchanger isoforms in mouse endometrial epithelium. Wang, X.F., Yu, M.K., Lam, S.Y., Leung, K.M., Jiang, J.L., Leung, P.S., Ko, W.H., Leung, P.Y., Chew, S.B., Liu, C.Q., Tse, C.M., Chan, H.C. Biol. Reprod. (2003)
- NHE2 is the main apical NHE in mouse colonic crypts but an alternative Na+-dependent acid extrusion mechanism is upregulated in NHE2-null mice. Guan, Y., Dong, J., Tackett, L., Meyer, J.W., Shull, G.E., Montrose, M.H. Am. J. Physiol. Gastrointest. Liver Physiol. (2006)
- NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice. Bailey, M.A., Giebisch, G., Abbiati, T., Aronson, P.S., Gawenis, L.R., Shull, G.E., Wang, T. J. Physiol. (Lond.) (2004)
- Differential expression of ileal Na(+)/H(+) exchanger isoforms after enterectomy. Falcone, R.A., Shin, C.E., Stern, L.E., Wang, Z., Erwin, C.R., Soleimani, M., Warner, B.W. J. Surg. Res. (1999)
- Transcriptional regulation of rat Na(+)/H(+) exchanger isoform-2 (NHE-2) gene by Sp1 transcription factor. Bai, L., Collins, J.F., Xu, H., Ghishan, F.K. Am. J. Physiol., Cell Physiol. (2001)
- Kidney cortex cells derived from SV40 transgenic mice retain intrinsic properties of polarized proximal tubule cells. Chalumeau, C., Lamblin, D., Bourgeois, S., Borensztein, P., Chambrey, R., Bruneval, P., Huyen, J.P., Froissart, M., Biber, J., Paillard, M., Kellermann, O., Poggioli, J. Kidney Int. (1999)