Gene Review:
Slc9a3 - solute carrier family 9 (sodium/hydrogen...
Mus musculus
Synonyms:
9030624O13Rik, AI930210, NHE-3, NHE3
Weinman,
Steplock,
Wade,
Shenolikar,
Good,
Watts,
George,
Meyer,
Shull,
Praetorius,
Andreasen,
Jensen,
Ainsworth,
Friis,
Johansen,
du Cheyron,
Chalumeau,
Defontaine,
Klein,
Kellermann,
Paillard,
Poggioli,
Weinman,
Steplock,
Shenolikar,
- Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2. Ledoussal, C., Lorenz, J.N., Nieman, M.L., Soleimani, M., Schultheis, P.J., Shull, G.E. Am. J. Physiol. Renal Physiol. (2001)
- Endothelin-1/endothelin-B receptor-mediated increases in NHE3 activity in chronic metabolic acidosis. Laghmani, K., Preisig, P.A., Moe, O.W., Yanagisawa, M., Alpern, R.J. J. Clin. Invest. (2001)
- In vivo evidence for interferon-gamma-mediated homeostatic mechanisms in small intestine of the NHE3 Na+/H+ exchanger knockout model of congenital diarrhea. Woo, A.L., Gildea, L.A., Tack, L.M., Miller, M.L., Spicer, Z., Millhorn, D.E., Finkelman, F.D., Hassett, D.J., Shull, G.E. J. Biol. Chem. (2002)
- Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect. Woo, A.L., Noonan, W.T., Schultheis, P.J., Neumann, J.C., Manning, P.A., Lorenz, J.N., Shull, G.E. Am. J. Physiol. Renal Physiol. (2003)
- Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Schultheis, P.J., Clarke, L.L., Meneton, P., Miller, M.L., Soleimani, M., Gawenis, L.R., Riddle, T.M., Duffy, J.J., Doetschman, T., Wang, T., Giebisch, G., Aronson, P.S., Lorenz, J.N., Shull, G.E. Nat. Genet. (1998)
- ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease. Piwon, N., Günther, W., Schwake, M., Bösl, M.R., Jentsch, T.J. Nature (2000)
- Targeted disruption of the Nhe1 gene prevents muscarinic agonist-induced up-regulation of Na(+)/H(+) exchange in mouse parotid acinar cells. Evans, R.L., Bell, S.M., Schultheis, P.J., Shull, G.E., Melvin, J.E. J. Biol. Chem. (1999)
- Defective fluid secretion and NaCl absorption in the parotid glands of Na+/H+ exchanger-deficient mice. Park, K., Evans, R.L., Watson, G.E., Nehrke, K., Richardson, L., Bell, S.M., Schultheis, P.J., Hand, A.R., Shull, G.E., Melvin, J.E. J. Biol. Chem. (2001)
- NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes. Weinman, E.J., Steplock, D., Shenolikar, S. FEBS Lett. (2003)
- Regulatory interaction between the cystic fibrosis transmembrane conductance regulator and HCO3- salvage mechanisms in model systems and the mouse pancreatic duct. Ahn, W., Kim, K.H., Lee, J.A., Kim, J.Y., Choi, J.Y., Moe, O.W., Milgram, S.L., Muallem, S., Lee, M.G. J. Biol. Chem. (2001)
- Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct. Lee, M.G., Ahn, W., Choi, J.Y., Luo, X., Seo, J.T., Schultheis, P.J., Shull, G.E., Kim, K.H., Muallem, S. J. Clin. Invest. (2000)
- slc26a3 (dra)-deficient Mice Display Chloride-losing Diarrhea, Enhanced Colonic Proliferation, and Distinct Up-regulation of Ion Transporters in the Colon. Schweinfest, C.W., Spyropoulos, D.D., Henderson, K.W., Kim, J.H., Chapman, J.M., Barone, S., Worrell, R.T., Wang, Z., Soleimani, M. J. Biol. Chem. (2006)
- Loss of the NHE2 Na(+)/H(+) exchanger has no apparent effect on diarrheal state of NHE3-deficient mice. Ledoussal, C., Woo, A.L., Miller, M.L., Shull, G.E. Am. J. Physiol. Gastrointest. Liver Physiol. (2001)
- HCO3- salvage mechanisms in the submandibular gland acinar and duct cells. Luo, X., Choi, J.Y., Ko, S.B., Pushkin, A., Kurtz, I., Ahn, W., Lee, M.G., Muallem, S. J. Biol. Chem. (2001)
- Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na(+)/H(+) exchange in OK cells. Weinman, E.J., Steplock, D., Wade, J.B., Shenolikar, S. Am. J. Physiol. Renal Physiol. (2001)
- Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse. Wade, J.B., Liu, J., Coleman, R.A., Cunningham, R., Steplock, D.A., Lee-Kwon, W., Pallone, T.L., Shenolikar, S., Weinman, E.J. Am. J. Physiol., Cell Physiol. (2003)
- Defective parathyroid hormone regulation of NHE3 activity and phosphate adaptation in cultured NHERF-1-/- renal proximal tubule cells. Cunningham, R., Steplock, D., Wang, F., Huang, H., E, X., Shenolikar, S., Weinman, E.J. J. Biol. Chem. (2004)
- Transepithelial HCO3- absorption is defective in renal thick ascending limbs from Na+/H+ exchanger NHE1 null mutant mice. Good, D.W., Watts, B.A., George, T., Meyer, J.W., Shull, G.E. Am. J. Physiol. Renal Physiol. (2004)
- Differential expression of ileal Na(+)/H(+) exchanger isoforms after enterectomy. Falcone, R.A., Shin, C.E., Stern, L.E., Wang, Z., Erwin, C.R., Soleimani, M., Warner, B.W. J. Surg. Res. (1999)
- Kidney cortex cells derived from SV40 transgenic mice retain intrinsic properties of polarized proximal tubule cells. Chalumeau, C., Lamblin, D., Bourgeois, S., Borensztein, P., Chambrey, R., Bruneval, P., Huyen, J.P., Froissart, M., Biber, J., Paillard, M., Kellermann, O., Poggioli, J. Kidney Int. (1999)
- Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1. Capuano, P., Bacic, D., Stange, G., Hernando, N., Kaissling, B., Pal, R., Kocher, O., Biber, J., Wagner, C.A., Murer, H. Pflugers Arch. (2005)
- Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics. Brooks, H.L., Sorensen, A.M., Terris, J., Schultheis, P.J., Lorenz, J.N., Shull, G.E., Knepper, M.A. J. Physiol. (Lond.) (2001)
- NHE1, NHE2, and NHE3 contribute to regulation of intracellular pH in murine duodenal epithelial cells. Praetorius, J., Andreasen, D., Jensen, B.L., Ainsworth, M.A., Friis, U.G., Johansen, T. Am. J. Physiol. Gastrointest. Liver Physiol. (2000)
- Angiotensin II stimulates NHE3 activity by exocytic insertion of the transporter: role of PI 3-kinase. du Cheyron, D., Chalumeau, C., Defontaine, N., Klein, C., Kellermann, O., Paillard, M., Poggioli, J. Kidney Int. (2003)
- NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice. Bailey, M.A., Giebisch, G., Abbiati, T., Aronson, P.S., Gawenis, L.R., Shull, G.E., Wang, T. J. Physiol. (Lond.) (2004)