Gene Review:
Tnni3 - troponin I type 3 (cardiac)
Rattus norvegicus
Synonyms:
Cardiac troponin I, Ctni, TnI, Tni, Troponin I, cardiac muscle, ...
- Histidine button engineered into cardiac troponin I protects the ischemic and failing heart. Day, S.M., Westfall, M.V., Fomicheva, E.V., Hoyer, K., Yasuda, S., La Cross, N.C., D'Alecy, L.G., Ingwall, J.S., Metzger, J.M. Nat. Med. (2006)
- Role of troponin I proteolysis in the pathogenesis of stunned myocardium. Gao, W.D., Atar, D., Liu, Y., Perez, N.G., Murphy, A.M., Marban, E. Circ. Res. (1997)
- Troponin I degradation and covalent complex formation accompanies myocardial ischemia/reperfusion injury. McDonough, J.L., Arrell, D.K., Van Eyk, J.E. Circ. Res. (1999)
- Altered phosphorylation and calcium sensitivity of cardiac myofibrillar proteins during sepsis. Wu, L.L., Tang, C., Liu, M.S. Am. J. Physiol. Regul. Integr. Comp. Physiol. (2001)
- Molecular basis of depression of Ca2+ sensitivity of tension by acid pH in cardiac muscles of the mouse and the rat. Ding, X.L., Akella, A.B., Sonnenblick, E.H., Rao, V.G., Gulati, J. J. Card. Fail. (1996)
- Thin filament protein dynamics in fully differentiated adult cardiac myocytes: toward a model of sarcomere maintenance. Michele, D.E., Albayya, F.P., Metzger, J.M. J. Cell Biol. (1999)
- Preload induces troponin I degradation independently of myocardial ischemia. Feng, J., Schaus, B.J., Fallavollita, J.A., Lee, T.C., Canty, J.M. Circulation (2001)
- Calpain-mediated proteolytic cleavage of troponin I induced by hypoxia or metabolic inhibition in cultured neonatal cardiomyocytes. Kositprapa, C., Zhang, B., Berger, S., Canty, J.M., Lee, T.C. Mol. Cell. Biochem. (2000)
- Altered phosphorylation of sarcoplasmic reticulum contributes to the diminished contractile response to isoproterenol in hypertrophied rat hearts. Szymanska, G., Strömer, H., Silverman, M., Belu-John, Y., Morgan, J.P. Pflugers Arch. (1999)
- Developmental expression of rat cardiac troponin I mRNA. Ausoni, S., De Nardi, C., Moretti, P., Gorza, L., Schiaffino, S. Development (1991)
- Experimental diabetes is associated with functional activation of protein kinase C epsilon and phosphorylation of troponin I in the heart, which are prevented by angiotensin II receptor blockade. Malhotra, A., Reich, D., Reich, D., Nakouzi, A., Sanghi, V., Geenen, D.L., Buttrick, P.M. Circ. Res. (1997)
- Protein kinase C phosphorylation of cardiac troponin I and troponin T inhibits Ca(2+)-stimulated MgATPase activity in reconstituted actomyosin and isolated myofibrils, and decreases actin-myosin interactions. Noland, T.A., Kuo, J.F. J. Mol. Cell. Cardiol. (1993)
- Structure and regulation of the mouse cardiac troponin I gene. Ausoni, S., Campione, M., Picard, A., Moretti, P., Vitadello, M., De Nardi, C., Schiaffino, S. J. Biol. Chem. (1994)
- Switching of troponin I: Ca(2+) and myosin-induced activation of heart muscle. Robinson, J.M., Dong, W.J., Xing, J., Cheung, H.C. J. Mol. Biol. (2004)
- Role of troponin I phosphorylation in protein kinase C-mediated enhanced contractile performance of rat myocytes. Westfall, M.V., Borton, A.R. J. Biol. Chem. (2003)
- Differential regulation of cardiac actomyosin S-1 MgATPase by protein kinase C isozyme-specific phosphorylation of specific sites in cardiac troponin I and its phosphorylation site mutants. Noland, T.A., Raynor, R.L., Jideama, N.M., Guo, X., Kazanietz, M.G., Blumberg, P.M., Solaro, R.J., Kuo, J.F. Biochemistry (1996)
- Propofol increases phosphorylation of troponin I and myosin light chain 2 via protein kinase C activation in cardiomyocytes. Kanaya, N., Gable, B., Murray, P.A., Damron, D.S. Anesthesiology (2003)
- Arachidonic acid-dependent phosphorylation of troponin I and myosin light chain 2 in cardiac myocytes. Damron, D.S., Darvish, A., Murphy, L., Sweet, W., Moravec, C.S., Bond, M. Circ. Res. (1995)
- Protein kinase C-mediated phosphorylation of troponin I and C-protein in isolated myocardial cells is associated with inhibition of myofibrillar actomyosin MgATPase. Venema, R.C., Kuo, J.F. J. Biol. Chem. (1993)
- Specific degradation of troponin T and I by mu-calpain and its modulation by substrate phosphorylation. Di Lisa, F., De Tullio, R., Salamino, F., Barbato, R., Melloni, E., Siliprandi, N., Schiaffino, S., Pontremoli, S. Biochem. J. (1995)
- Identification and functional significance of troponin I isoforms in neonatal rat heart myofibrils. Martin, A.F., Ball, K., Gao, L.Z., Kumar, P., Solaro, R.J. Circ. Res. (1991)
- Sarcomere thin filament regulatory isoforms. Evidence of a dominant effect of slow skeletal troponin I on cardiac contraction. Metzger, J.M., Michele, D.E., Rust, E.M., Borton, A.R., Westfall, M.V. J. Biol. Chem. (2003)