Gene Review:
sli - slit
Drosophila melanogaster
Synonyms:
CG33464, CG43758, CG8355, CT21700, CT37068, ...
- Comm sorts robo to control axon guidance at the Drosophila midline. Keleman, K., Rajagopalan, S., Cleppien, D., Teis, D., Paiha, K., Huber, L.A., Technau, G.M., Dickson, B.J. Cell (2002)
- slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system. Rothberg, J.M., Hartley, D.A., Walther, Z., Artavanis-Tsakonas, S. Cell (1988)
- Neurobiology. Slit, the midline repellent. Harris, W.A., Holt, C.E. Nature (1999)
- The microtubule plus end tracking protein Orbit/MAST/CLASP acts downstream of the tyrosine kinase Abl in mediating axon guidance. Lee, H., Engel, U., Rusch, J., Scherrer, S., Sheard, K., Van Vactor, D. Neuron (2004)
- Genetic specification of axonal arbors: atonal regulates robo3 to position terminal branches in the Drosophila nervous system. Zlatic, M., Landgraf, M., Bate, M. Neuron (2003)
- Slit signaling promotes the terminal asymmetric division of neural precursor cells in the Drosophila CNS. Mehta, B., Bhat, K.M. Development (2001)
- Lateral positioning at the dorsal midline: Slit and Roundabout receptors guide Drosophila heart cell migration. Santiago-Martínez, E., Soplop, N.H., Kramer, S.G. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Compartmentalization of visual centers in the Drosophila brain requires Slit and Robo proteins. Tayler, T.D., Robichaux, M.B., Garrity, P.A. Development (2004)
- Roundabout 2 regulates migration of sensory neurons by signaling in trans. Kraut, R., Zinn, K. Curr. Biol. (2004)
- Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of Slit. Howitt, J.A., Clout, N.J., Hohenester, E. EMBO J. (2004)
- Receptor tyrosine phosphatases regulate axon guidance across the midline of the Drosophila embryo. Sun, Q., Bahri, S., Schmid, A., Chia, W., Zinn, K. Development (2000)
- Attractive and repulsive functions of Slit are mediated by different receptors in the Drosophila trachea. Englund, C., Steneberg, P., Falileeva, L., Xylourgidis, N., Samakovlis, C. Development (2002)
- Heparan sulfate proteoglycan syndecan promotes axonal and myotube guidance by slit/robo signaling. Steigemann, P., Molitor, A., Fellert, S., Jäckle, H., Vorbrüggen, G. Curr. Biol. (2004)
- Independent functions of Slit-Robo repulsion and Netrin-Frazzled attraction regulate axon crossing at the midline in Drosophila. Garbe, D.S., Bashaw, G.J. J. Neurosci. (2007)
- Repellent signaling by Slit requires the leucine-rich repeats. Battye, R., Stevens, A., Perry, R.L., Jacobs, J.R. J. Neurosci. (2001)
- Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons. Li, H.S., Chen, J.H., Wu, W., Fagaly, T., Zhou, L., Yuan, W., Dupuis, S., Jiang, Z.H., Nash, W., Gick, C., Ornitz, D.M., Wu, J.Y., Rao, Y. Cell (1999)
- Short-range and long-range guidance by Slit and its Robo receptors: a combinatorial code of Robo receptors controls lateral position. Simpson, J.H., Bland, K.S., Fetter, R.D., Goodman, C.S. Cell (2000)
- The Drosophila ARF6-GEF Schizo controls commissure formation by regulating Slit. Onel, S., Bolke, L., Klämbt, C. Development (2004)
- Positioning sensory terminals in the olfactory lobe of Drosophila by Robo signaling. Jhaveri, D., Saharan, S., Sen, A., Rodrigues, V. Development (2004)
- A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Wills, Z., Emerson, M., Rusch, J., Bikoff, J., Baum, B., Perrimon, N., Van Vactor, D. Neuron (2002)
- Rhomboid 3 orchestrates Slit-independent repulsion of tracheal branches at the CNS midline. Gallio, M., Englund, C., Kylsten, P., Samakovlis, C. Development (2004)