Gene Review:
KEL - Kell blood group, metallo-endopeptidase
Homo sapiens
Synonyms:
CD238, ECE3, Kell blood group glycoprotein
- A combination of the effects of rare genotypes at the XK and KEL blood group loci results in absence of Kell system antigens from the red blood cells. Daniels, G.L., Weinauer, F., Stone, C., Ho, M., Green, C.A., Jahn-Jochem, H., Offner, R., Monaco, A.P. Blood (1996)
- Molecular basis of the Kell (K1) phenotype. Lee, S., Wu, X., Reid, M., Zelinski, T., Redman, C. Blood (1995)
- Organization of the gene encoding the human Kell blood group protein. Lee, S., Zambas, E., Green, E.D., Redman, C. Blood (1995)
- Molecular defects underlying the Kell null phenotype. Lee, S., Russo, D.C., Reiner, A.P., Lee, J.H., Sy, M.Y., Telen, M.J., Judd, W.J., Simon, P., Rodrigues, M.J., Chabert, T., Poole, J., Jovanovic-Srzentic, S., Levene, C., Yahalom, V., Redman, C.M. J. Biol. Chem. (2001)
- Molecular basis of the Kell-null phenotype: a mutation at the splice site of human KEL gene abolishes the expression of Kell blood group antigens. Yu, L.C., Twu, Y.C., Chang, C.Y., Lin, M. J. Biol. Chem. (2001)
- Fetal blood group genotyping: present and future. Daniels, G., Finning, K., Martin, P., Summers, J. Ann. N. Y. Acad. Sci. (2006)
- Regional chromosomal assignment of the Kell blood group locus (KEL) to chromosome 7q33-q35 by fluorescence in situ hybridization: evidence for the polypeptide nature of antigenic variation. Murphy, M.T., Morrison, N., Miles, J.S., Fraser, R.H., Spurr, N.K., Boyd, E. Hum. Genet. (1993)
- The KEL24 and KEL14 alleles of the Kell blood group system. Lee, S., Naime, D., Reid, M., Redman, C. Transfusion (1997)
- Transcriptional regulation of the KEL gene and Kell protein expression in erythroid and non-erythroid cells. Camara-Clayette, V., Rahuel, C., Lopez, C., Hattab, C., Verkarre, V., Bertrand, O., Cartron, J.P. Biochem. J. (2001)
- Characterization of murine monoclonal antibodies directed against the Kell blood group glycoprotein. Jaber, A., Loirat, M.J., Willem, C., Bloy, C., Cartron, J.P., Blanchard, D. Br. J. Haematol. (1991)
- Heterozygosity for two novel null alleles of the KEL gene causes the Kell-null phenotype in a Japanese woman. Koda, Y., Soejima, M., Tsuneoka, M., Yasumoto, K., Higashitani, T., Sagawa, K., Kimura, H. Br. J. Haematol. (2002)
- Point mutations in KEL exon 8 determine a high-incidence (RAZ) and a low-incidence (KEL25, VLAN) antigen of the Kell blood group system. Lee, S., Reid, M.E., Redman, C.M. Vox Sang. (2001)
- Separation of human erythrocyte membrane associated proteins with one-dimensional and two-dimensional gel electrophoresis followed by identification with matrix-assisted laser desorption/ionization-time of flight mass spectrometry. Low, T.Y., Seow, T.K., Chung, M.C. Proteomics (2002)
- Genetic diversity of KELnull and KELel: a nationwide Austrian survey. Körmöczi, G.F., Wagner, T., Jungbauer, C., Vadon, M., Ahrens, N., Moll, W., Mühlbacher, A., Ozgül-Gülce, S., Kleinrath, T., Kilga-Nogler, S., Schönitzer, D., Gassner, C. Transfusion (2007)
- Molecular basis of two novel high-prevalence antigens in the Kell blood group system, KALT and KTIM. Lee, S., Debnath, A.K., Wu, X., Scofield, T., George, T., Kakaiya, R., Yogore, M.G., Sausais, L., Yacob, M., Lomas-Francis, C., Reid, M.E. Transfusion (2006)
- Linkage relations of JK, CO, KEL and IGK with each other and with AHCY. Bender, K., Bissbort, S., Crone, H., Senff, H., Steiert, A., Neumann, H., Koch, M., Nagel, M., Wienker, T.F. Hum. Hered. (1988)
- Exclusion of unassigned blood group system loci from the regulator of complement activation gene cluster on chromosome 1q32. Lewis, M., Kaita, H., Philipps, S., McAlpine, P.J., Wong, P. Vox Sang. (1989)
- Genetic linkage between the Kell blood group system and prolactin-inducible protein loci: provisional assignment of KEL to chromosome 7. Zelinski, T., Coghlan, G., Myal, Y., Shiu, R.P., Philipps, S., White, L., Lewis, M. Ann. Hum. Genet. (1991)
- The human Kell blood group gene maps to chromosome 7q33 and its expression is restricted to erythroid cells. Lee, S., Zambas, E.D., Marsh, W.L., Redman, C.M. Blood (1993)
- Molecular basis of the K:6,-7 [Js(a+b-)] phenotype in the Kell blood group system. Lee, S., Wu, X., Reid, M., Redman, C. Transfusion (1995)
- Additional red blood cell alloantibodies after blood transfusions in a nonhematologic alloimmunized patient cohort: is it time to take precautionary measures? Schonewille, H., van de Watering, L.M., Brand, A. Transfusion (2006)
- Molecular basis of Kell blood group phenotypes. Lee, S. Vox Sang. (1997)