Gene Review:
KLRD1 - killer cell lectin-like receptor subfamily...
Homo sapiens
Synonyms:
CD94, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94
López-Botet,
Pérez-Villar,
Carretero,
Rodríguez,
Melero,
Bellón,
Llano,
Navarro,
Radaev,
Sun,
Plougastel,
Trowsdale,
O'Callaghan,
Bell,
Borrego,
Kabat,
Sanni,
Coligan,
Braud,
Allan,
O'Callaghan,
Söderström,
D'Andrea,
Ogg,
Lazetic,
Young,
Bell,
Phillips,
Lanier,
McMichael,
Tanaka,
Toubai,
Tsutsumi,
Miura,
Kato,
Umehara,
Kahata,
Mori,
Toyoshima,
Ota,
Kobayashi,
Kobayashi,
Kasai,
Asaka,
Imamura,
Miller,
McCullar,
Eichler,
Ruschpler,
Wobus,
Drössler,
- Imprint of human cytomegalovirus infection on the NK cell receptor repertoire. Gumá, M., Angulo, A., Vilches, C., Gómez-Lozano, N., Malats, N., López-Botet, M. Blood (2004)
- Cytolytic activity and regulatory functions of inhibitory NK cell receptor-expressing T cells expanded from granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cells. Tanaka, J., Toubai, T., Tsutsumi, Y., Miura, Y., Kato, N., Umehara, S., Kahata, K., Mori, A., Toyoshima, N., Ota, S., Kobayashi, T., Kobayashi, M., Kasai, M., Asaka, M., Imamura, M. Blood (2004)
- Functional modulation of expanded CD8+ synovial fluid T cells by NK cell receptor expression in HLA-B27-associated reactive arthritis. Dulphy, N., Rabian, C., Douay, C., Flinois, O., Laoussadi, S., Kuipers, J., Tamouza, R., Charron, D., Toubert, A. Int. Immunol. (2002)
- Variations of human killer cell lectin-like receptors: common occurrence of NKG2-C deletion in the general population. Hikami, K., Tsuchiya, N., Yabe, T., Tokunaga, K. Genes Immun. (2003)
- IFN-gamma protects short-term ovarian carcinoma cell lines from CTL lysis via a CD94/NKG2A-dependent mechanism. Malmberg, K.J., Levitsky, V., Norell, H., de Matos, C.T., Carlsten, M., Schedvins, K., Rabbani, H., Moretta, A., Söderström, K., Levitskaya, J., Kiessling, R. J. Clin. Invest. (2002)
- The specific regulation of immune responses by CD8+ T cells restricted by the MHC class Ib molecule, Qa-1. Jiang, H., Chess, L. Annu. Rev. Immunol. (2000)
- HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Braud, V.M., Allan, D.S., O'Callaghan, C.A., Söderström, K., D'Andrea, A., Ogg, G.S., Lazetic, S., Young, N.T., Bell, J.I., Phillips, J.H., Lanier, L.L., McMichael, A.J. Nature (1998)
- Characterization of functional surface structures on human natural killer cells. Ritz, J., Schmidt, R.E., Michon, J., Hercend, T., Schlossman, S.F. Adv. Immunol. (1988)
- Mutual activation of natural killer cells and monocytes mediated by NKp80-AICL interaction. Welte, S., Kuttruff, S., Waldhauer, I., Steinle, A. Nat. Immunol. (2006)
- Structure and function of natural killer cell surface receptors. Radaev, S., Sun, P.D. Annual review of biophysics and biomolecular structure. (2003)
- NK cell CD94/NKG2A inhibitory receptors are internalized and recycle independently of inhibitory signaling processes. Borrego, F., Kabat, J., Sanni, T.B., Coligan, J.E. J. Immunol. (2002)
- Mitogen-activated protein kinase activity is involved in effector functions triggered by the CD94/NKG2-C NK receptor specific for HLA-E. Carretero, M., Llano, M., Navarro, F., Bellón, T., López-Botet, M. Eur. J. Immunol. (2000)
- Linkage of the NKG2 and CD94 receptor genes to D12S77 in the human natural killer gene complex. Sobanov, Y., Glienke, J., Brostjan, C., Lehrach, H., Francis, F., Hofer, E. Immunogenetics (1999)
- Recognition of human histocompatibility leukocyte antigen (HLA)-E complexed with HLA class I signal sequence-derived peptides by CD94/NKG2 confers protection from natural killer cell-mediated lysis. Borrego, F., Ulbrecht, M., Weiss, E.H., Coligan, J.E., Brooks, A.G. J. Exp. Med. (1998)
- A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition. Michaëlsson, J., Teixeira de Matos, C., Achour, A., Lanier, L.L., Kärre, K., Söderström, K. J. Exp. Med. (2002)
- Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts. Gumá, M., Budt, M., Sáez, A., Brckalo, T., Hengel, H., Angulo, A., López-Botet, M. Blood (2006)
- Role that each NKG2A immunoreceptor tyrosine-based inhibitory motif plays in mediating the human CD94/NKG2A inhibitory signal. Kabat, J., Borrego, F., Brooks, A., Coligan, J.E. J. Immunol. (2002)
- Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily. Chang, C., Rodríguez, A., Carretero, M., López-Botet, M., Phillips, J.H., Lanier, L.L. Eur. J. Immunol. (1995)
- Prostaglandin E2 induces the expression of functional inhibitory CD94/NKG2A receptors in human CD8+ T lymphocytes by a cAMP-dependent protein kinase A type I pathway. Zeddou, M., Greimers, R., de Valensart, N., Nayjib, B., Tasken, K., Boniver, J., Moutschen, M., Rahmouni, S. Biochem. Pharmacol. (2005)
- Differentially induced expression of C-type lectins in activated lymphocytes. Eichler, W., Ruschpler, P., Wobus, M., Drössler, K. J. Cell. Biochem. Suppl. (2001)
- HLA-E-bound peptides influence recognition by inhibitory and triggering CD94/NKG2 receptors: preferential response to an HLA-G-derived nonamer. Llano, M., Lee, N., Navarro, F., García, P., Albar, J.P., Geraghty, D.E., López-Botet, M. Eur. J. Immunol. (1998)
- Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells. Allan, D.S., Colonna, M., Lanier, L.L., Churakova, T.D., Abrams, J.S., Ellis, S.A., McMichael, A.J., Braud, V.M. J. Exp. Med. (1999)
- The CD94/NKG2 C-type lectin receptor complex: involvement in NK cell-mediated recognition of HLA class I molecules. López-Botet, M., Carretero, M., Pérez-Villar, J., Bellón, T., Llano, M., Navarro, F. Immunol. Res. (1997)
- HLA-E is expressed on trophoblast and interacts with CD94/NKG2 receptors on decidual NK cells. King, A., Allan, D.S., Bowen, M., Powis, S.J., Joseph, S., Verma, S., Hiby, S.E., McMichael, A.J., Loke, Y.W., Braud, V.M. Eur. J. Immunol. (2000)
- The CD94/NKG2C killer lectin-like receptor constitutes an alternative activation pathway for a subset of CD8+ T cells. Gumá, M., Busch, L.K., Salazar-Fontana, L.I., Bellosillo, B., Morte, C., García, P., López-Botet, M. Eur. J. Immunol. (2005)
- Structure and function of the human MHC class Ib molecules HLA-E, HLA-F and HLA-G. O'Callaghan, C.A., Bell, J.I. Immunol. Rev. (1998)
- The role of CD94/NKG2 in innate and adaptive immunity. Gunturi, A., Berg, R.E., Forman, J. Immunol. Res. (2004)
- Cutting edge: engagement of CD160 by its HLA-C physiological ligand triggers a unique cytokine profile secretion in the cytotoxic peripheral blood NK cell subset. Barakonyi, A., Rabot, M., Marie-Cardine, A., Aguerre-Girr, M., Polgar, B., Schiavon, V., Bensussan, A., Le Bouteiller, P. J. Immunol. (2004)
- Human natural killer cells with polyclonal lectin and immunoglobulinlike receptors develop from single hematopoietic stem cells with preferential expression of NKG2A and KIR2DL2/L3/S2. Miller, J.S., McCullar, V. Blood (2001)
- Cloning of NKG2-F, a new member of the NKG2 family of human natural killer cell receptor genes. Plougastel, B., Trowsdale, J. Eur. J. Immunol. (1997)
- Structure and function of the CD94 C-type lectin receptor complex involved in recognition of HLA class I molecules. López-Botet, M., Pérez-Villar, J.J., Carretero, M., Rodríguez, A., Melero, I., Bellón, T., Llano, M., Navarro, F. Immunol. Rev. (1997)
- Triggering of effector functions on a CD8+ T cell clone upon the aggregation of an activatory CD94/kp39 heterodimer. Bellón, T., Heredia, A.B., Llano, M., Minguela, A., Rodriguez, A., López-Botet, M., Aparicio, P. J. Immunol. (1999)
- Molecular and functional characterization of NKG2D, NKp80, and NKG2C triggering NK cell receptors in rhesus and cynomolgus macaques: monitoring of NK cell function during simian HIV infection. Biassoni, R., Fogli, M., Cantoni, C., Costa, P., Conte, R., Koopman, G., Cafaro, A., Ensoli, B., Moretta, A., Moretta, L., De Maria, A. J. Immunol. (2005)
- Interleukin-15-induced maturation of human natural killer cells from early thymic precursors: selective expression of CD94/NKG2-A as the only HLA class I-specific inhibitory receptor. Mingari, M.C., Vitale, C., Cantoni, C., Bellomo, R., Ponte, M., Schiavetti, F., Bertone, S., Moretta, A., Moretta, L. Eur. J. Immunol. (1997)
- Direct binding of purified HLA class I antigens by soluble NKG2/CD94 C-type lectins from natural killer cells. Ding, Y., Sumitran, S., Holgersson, J. Scand. J. Immunol. (1999)