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Gene Review

TMF1  -  TATA element modulatory factor 1

Homo sapiens

Synonyms: ARA160, Androgen receptor coactivator 160 kDa protein, Androgen receptor-associated protein of 160 kDa, TATA element modulatory factor, TMF
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Disease relevance of TMF1


High impact information on TMF1


Biological context of TMF1


Anatomical context of TMF1

  • Transmitral (TMF), left atrial appendage (LAA), and pulmonary venous (PVF) Doppler flows were measured by TEE [10].

Associations of TMF1 with chemical compounds


Other interactions of TMF1

  • Like another proliferation promoting factor, Stat3, TRNP was directed to proteasomal degradation by TMF/ ARA160 [13].

Analytical, diagnostic and therapeutic context of TMF1

  • In situ hybridization analysis revealed the preferential accumulation of TMF transcripts in meiotic spermatogenic and oogenic cells. p94fer and p51ferT may thus modulate the suppressive activity of TMF during cellular growth and in defined differentiation processes [8].
  • An accurate TMFP presumably should increase during pericardiocentesis and correlate with left ventricular stroke work [3].
  • After the preoperative treatment all patients underwent mastectomy and complete axillary clearance, and then received 4-6 courses of TMF [14].
  • RESULTS: The January 1 - December 31, 2000 baseline Medicare claims for the January 1, 2001 prevalence cohort were provided to HTPN by TMF in October 2001, representing a ten-month lag in the ability of Quality Improvement Organizations to provide Part B data relative to a specific episode of care time frame [15].


  1. Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells. Hsiao, P.W., Chang, C. J. Biol. Chem. (1999) [Pubmed]
  2. Cloning and chromosomal mapping of a human immunodeficiency virus 1 "TATA" element modulatory factor. Garcia, J.A., Ou, S.H., Wu, F., Lusis, A.J., Sparkes, R.S., Gaynor, R.B. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  3. Ventricular performance related to transmural filling pressure in clinical cardiac tamponade. Boltwood, C.M. Circulation (1987) [Pubmed]
  4. Clinical trials on adjuvant chemotherapy for breast cancer. Semiglazov, V.F., Bavli, J.L., Moiseyenko, V.M., Rzhankov, S.V., Migmanova, N.S., Popova, R.T., Seleznyov, I.K., Kremen, B.V., Kostetskaya, T.V., Barash, N.J. Cancer (1986) [Pubmed]
  5. Alterations of insulin sensitivity by the implantation of 3T3-L1 cells in nude mice. A role for TNF-alpha? Shibasaki, M., Takahashi, K., Itou, T., Miyazawa, S., Ito, M., Kobayashi, J., Bujo, H., Saito, Y. Diabetologia (2002) [Pubmed]
  6. Solid-phase synthesis and biological activity of a combinatorial cross-conjugated dienone library. Kitade, M., Tanaka, H., Oe, S., Iwashima, M., Iguchi, K., Takahashi, T. Chemistry (Weinheim an der Bergstrasse, Germany) (2006) [Pubmed]
  7. A putative nuclear receptor coactivator (TMF/ARA160) associates with hbrm/hSNF2 alpha and BRG-1/hSNF2 beta and localizes in the Golgi apparatus. Mori, K., Kato, H. FEBS Lett. (2002) [Pubmed]
  8. Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases. Schwartz, Y., Ben-Dor, I., Navon, A., Motro, B., Nir, U. FEBS Lett. (1998) [Pubmed]
  9. Characterization of a novel human gene containing ANK repeats and ARM domains. Occhi, G., Olivieri, M., Rampazzo, A., Danieli, G.A. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
  10. Extensive ablation during pulmonary vein antrum isolation has no adverse impact on left atrial function: an echocardiography and cine computed tomography analysis. Verma, A., Kilicaslan, F., Adams, J.R., Hao, S., Beheiry, S., Minor, S., Ozduran, V., Claude Elayi, S., Martin, D.O., Schweikert, R.A., Saliba, W., Thomas, J.D., Garcia, M., Klein, A., Natale, A. J. Cardiovasc. Electrophysiol. (2006) [Pubmed]
  11. Biomagnification of alpha- and gamma-hexabromocyclododecane isomers in a Lake Ontario food web. Tomy, G.T., Budakowski, W., Halldorson, T., Whittle, D.M., Keir, M.J., Marvin, C., MacInnis, G., Alaee, M. Environ. Sci. Technol. (2004) [Pubmed]
  12. Effects of dobutamine and enoximone on transmitral and pulmonary venous flow characteristics in patients with left ventricular dysfunction after coronary artery bypass grafting. Vroom, M.B., van Wezel, H.B., vd Brink, R.B., vd Lee, R., Eijsman, L., Visser, C.A., van Zwieten, P.A. J. Cardiothorac. Vasc. Anesth. (1996) [Pubmed]
  13. trnp: A conserved mammalian gene encoding a nuclear protein that accelerates cell-cycle progression. Volpe, M., Shpungin, S., Barbi, C., Abrham, G., Malovani, H., Wides, R., Nir, U. DNA Cell Biol. (2006) [Pubmed]
  14. Primary (neoadjuvant) chemotherapy and radiotherapy compared with primary radiotherapy alone in stage IIb-IIIa breast cancer. Semiglazov, V.F., Topuzov, E.E., Bavli, J.L., Moiseyenko, V.M., Ivanova, O.A., Seleznev, I.K., Orlov, A.A., Barash, N.Y., Golubeva, O.M., Chepic, O.F. Ann. Oncol. (1994) [Pubmed]
  15. Health care provider quality improvement organization Medicare data-sharing: a diabetes quality improvement initiative. Ballard, D.J., Nicewander, D., Skinner, C. Proceedings / AMIA ... Annual Symposium. AMIA Symposium. (2002) [Pubmed]
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