Gene Review:
RTG2 - Rtg2p
Saccharomyces cerevisiae S288c
Synonyms:
NRF588, Retrograde regulation protein 2, YGL252C
Fent,
- RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Liao, X., Butow, R.A. Cell (1993)
- Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Liu, Z., Sekito, T., Spírek, M., Thornton, J., Butow, R.A. Mol. Cell (2003)
- Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria. Kaur, R., Castaño, I., Cormack, B.P. Antimicrob. Agents Chemother. (2004)
- A novel Rtg2p activity regulates nitrogen catabolism in yeast. Pierce, M.M., Maddelein, M.L., Roberts, B.T., Wickner, R.B. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Rtg2 protein links metabolism and genome stability in yeast longevity. Borghouts, C., Benguria, A., Wawryn, J., Jazwinski, S.M. Genetics (2004)
- RTG-dependent mitochondria to nucleus signaling is negatively regulated by the seven WD-repeat protein Lst8p. Liu, Z., Sekito, T., Epstein, C.B., Butow, R.A. EMBO J. (2001)
- Mks1 in concert with TOR signaling negatively regulates RTG target gene expression in S. cerevisiae. Dilova, I., Chen, C.Y., Powers, T. Curr. Biol. (2002)
- Enzymatic and metabolic studies on retrograde regulation mutants of yeast. Small, W.C., Brodeur, R.D., Sandor, A., Fedorova, N., Li, G., Butow, R.A., Srere, P.A. Biochemistry (1995)
- Genome-wide responses to mitochondrial dysfunction. Epstein, C.B., Waddle, J.A., Hale, W., Davé, V., Thornton, J., Macatee, T.L., Garner, H.R., Butow, R.A. Mol. Biol. Cell (2001)
- Comparative analysis of estrogenic activity in sewage treatment plant effluents involving three in vitro assays and chemical analysis of steroids. Rutishauser, B.V., Pesonen, M., Escher, B.I., Ackermann, G.E., Aerni, H.R., Suter, M.J., Eggen, R.I. Environ. Toxicol. Chem. (2004)
- Fish cell lines as versatile tools in ecotoxicology: assessment of cytotoxicity, cytochrome P4501A induction potential and estrogenic activity of chemicals and environmental samples. Fent, K. Toxicology in vitro : an international journal published in association with BIBRA. (2001)
- RTG genes in yeast that function in communication between mitochondria and the nucleus are also required for expression of genes encoding peroxisomal proteins. Chelstowska, A., Butow, R.A. J. Biol. Chem. (1995)
- The Saccharomyces cerevisiae RTG2 gene is a regulator of aconitase expression under catabolite repression conditions. Vélot, C., Haviernik, P., Lauquin, G.J. Genetics (1996)
- Signalling between mitochondria and the nucleus regulates the expression of a new D-lactate dehydrogenase activity in yeast. Chelstowska, A., Liu, Z., Jia, Y., Amberg, D., Butow, R.A. Yeast (1999)
- Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Sekito, T., Thornton, J., Butow, R.A. Mol. Biol. Cell (2000)
- A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1. Liu, Z., Spírek, M., Thornton, J., Butow, R.A. Mol. Biol. Cell (2005)
- Interaction between Rtg2p and Mks1p in the regulation of the RTG pathway of Saccharomyces cerevisiae. Ferreira Júnior, J.R., Spírek, M., Liu, Z., Butow, R.A. Gene (2005)
- The histone acetyltransferase GCN5 modulates the retrograde response and genome stability determining yeast longevity. Kim, S., Ohkuni, K., Couplan, E., Jazwinski, S.M. Biogerontology. (2004)