Gene Review:
GSH1 - glutamate--cysteine ligase
Saccharomyces cerevisiae S288c
Synonyms:
GCS, Gamma-ECS, Gamma-glutamylcysteine synthetase, Glutamate--cysteine ligase, J0832, ...
- The role of glutathione in yeast dehydration tolerance. Espindola, A.d.e. .S., Gomes, D.S., Panek, A.D., Eleutherio, E.C. Cryobiology (2003)
- Glutathione synthesis in Streptococcus agalactiae. One protein accounts for gamma-glutamylcysteine synthetase and glutathione synthetase activities. Janowiak, B.E., Griffith, O.W. J. Biol. Chem. (2005)
- Molecular cloning and nucleotide sequencing of the gamma-glutamylcysteine synthetase gene of the fission yeast Schizosaccharomyces pombe. Mutoh, N., Nakagawa, C.W., Hayashi, Y. J. Biochem. (1995)
- Cadmium is an inducer of oxidative stress in yeast. Brennan, R.J., Schiestl, R.H. Mutat. Res. (1996)
- Sulfur assimilation and glutathione metabolism under cadmium stress in yeast, protists and plants. Mendoza-Cózatl, D., Loza-Tavera, H., Hernández-Navarro, A., Moreno-Sánchez, R. FEMS Microbiol. Rev. (2005)
- GSH1, which encodes gamma-glutamylcysteine synthetase, is a target gene for yAP-1 transcriptional regulation. Wu, A.L., Moye-Rowley, W.S. Mol. Cell. Biol. (1994)
- Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine. Grant, C.M., MacIver, F.H., Dawes, I.W. Mol. Biol. Cell (1997)
- The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae. Stephen, D.W., Rivers, S.L., Jamieson, D.J. Mol. Microbiol. (1995)
- Mutational analysis of Yap1 protein, an AP-1-like transcriptional activator of Saccharomyces cerevisiae. Takeuchi, T., Miyahara, K., Hirata, D., Miyakawa, T. FEBS Lett. (1997)
- The adaptive response of Saccharomyces cerevisiae to mercury exposure. Westwater, J., McLaren, N.F., Dormer, U.H., Jamieson, D.J. Yeast (2002)
- Coupling of the transcriptional regulation of glutathione biosynthesis to the availability of glutathione and methionine via the Met4 and Yap1 transcription factors. Wheeler, G.L., Trotter, E.W., Dawes, I.W., Grant, C.M. J. Biol. Chem. (2003)
- Amino acid-dependent regulation of the Saccharomyces cerevisiae GSH1 gene by hydrogen peroxide. Stephen, D.W., Jamieson, D.J. Mol. Microbiol. (1997)
- Glutathione regulates the expression of gamma-glutamylcysteine synthetase via the Met4 transcription factor. Wheeler, G.L., Quinn, K.A., Perrone, G., Dawes, I.W., Grant, C.M. Mol. Microbiol. (2002)
- Accumulation of cadmium ions in the methylotrophic yeast Hansenula polymorpha. Blazhenko, O.V., Zimmermann, M., Kang, H.A., Bartosz, G., Penninckx, M.J., Ubiyvovk, V.M., Sibirny, A.A. Biometals (2006)
- Glutathione synthetase from Plasmodium falciparum. Meierjohann, S., Walter, R.D., Müller, S. Biochem. J. (2002)
- The Yap1p-dependent induction of glutathione synthesis in heat shock response of Saccharomyces cerevisiae. Sugiyama, K., Izawa, S., Inoue, Y. J. Biol. Chem. (2000)
- Regulation of cadmium uptake by Saccharomyces cerevisiae. Gomes, D.S., Fragoso, L.C., Riger, C.J., Panek, A.D., Eleutherio, E.C. Biochim. Biophys. Acta (2002)
- Maturation of cytosolic iron-sulfur proteins requires glutathione. Sipos, K., Lange, H., Fekete, Z., Ullmann, P., Lill, R., Kispal, G. J. Biol. Chem. (2002)
- Cadmium-inducible expression of the yeast GSH1 gene requires a functional sulfur-amino acid regulatory network. Dormer, U.H., Westwater, J., McLaren, N.F., Kent, N.A., Mellor, J., Jamieson, D.J. J. Biol. Chem. (2000)
- Molecular cloning of Drosophila gamma-glutamylcysteine synthetase by functional complementation of a yeast mutant. Saunders, R.D., McLellan, L.I. FEBS Lett. (2000)
- A high copy number of yeast gamma-glutamylcysteine synthetase suppresses a nuclear mutation affecting mitochondrial translation. Lisowsky, T. Curr. Genet. (1993)