Gene Review:
RHO1 - Rho family GTPase RHO1
Saccharomyces cerevisiae S288c
Synonyms:
GTP-binding protein RHO1, P9325.3, Rho-type GTPase 1, YPR165W
- The small GTP-binding protein Rho1p is localized on the Golgi apparatus and post-Golgi vesicles in Saccharomyces cerevisiae. McCaffrey, M., Johnson, J.S., Goud, B., Myers, A.M., Rossier, J., Popoff, M.R., Madaule, P., Boquet, P. J. Cell Biol. (1991)
- Molecular cloning and characterization of yeast rho GDP dissociation inhibitor. Masuda, T., Tanaka, K., Nonaka, H., Yamochi, W., Maeda, A., Takai, Y. J. Biol. Chem. (1994)
- Role of small G proteins in yeast cell polarization and wall biosynthesis. Cabib, E., Drgonová, J., Drgon, T. Annu. Rev. Biochem. (1998)
- The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2. Schmidt, A., Bickle, M., Beck, T., Hall, M.N. Cell (1997)
- The protein MAP-1B links GABA(C) receptors to the cytoskeleton at retinal synapses. Hanley, J.G., Koulen, P., Bedford, F., Gordon-Weeks, P.R., Moss, S.J. Nature (1999)
- Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway. Simon, M.N., De Virgilio, C., Souza, B., Pringle, J.R., Abo, A., Reed, S.I. Nature (1995)
- Rho1p, a yeast protein at the interface between cell polarization and morphogenesis. Drgonová, J., Drgon, T., Tanaka, K., Kollár, R., Chen, G.C., Ford, R.A., Chan, C.S., Takai, Y., Cabib, E. Science (1996)
- A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae. Nonaka, H., Tanaka, K., Hirano, H., Fujiwara, T., Kohno, H., Umikawa, M., Mino, A., Takai, Y. EMBO J. (1995)
- Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae. Ozaki, K., Tanaka, K., Imamura, H., Hihara, T., Kameyama, T., Nonaka, H., Hirano, H., Matsuura, Y., Takai, Y. EMBO J. (1996)
- Rom2p, the Rho1 GTP/GDP exchange factor of Saccharomyces cerevisiae, can mediate stress responses via the Ras-cAMP pathway. Park, J.I., Collinson, E.J., Grant, C.M., Dawes, I.W. J. Biol. Chem. (2005)
- The GTP-binding protein Rho1p is required for cell cycle progression and polarization of the yeast cell. Drgonová, J., Drgon, T., Roh, D.H., Cabib, E. J. Cell Biol. (1999)
- Cell wall integrity modulates RHO1 activity via the exchange factor ROM2. Bickle, M., Delley, P.A., Schmidt, A., Hall, M.N. EMBO J. (1998)
- The RHO1-GAPs SAC7, BEM2 and BAG7 control distinct RHO1 functions in Saccharomyces cerevisiae. Schmidt, A., Schmelzle, T., Hall, M.N. Mol. Microbiol. (2002)
- Receptor internalization in yeast requires the Tor2-Rho1 signaling pathway. deHart, A.K., Schnell, J.D., Allen, D.A., Tsai, J.Y., Hicke, L. Mol. Biol. Cell (2003)
- Lack of GTP-bound Rho1p in secretory vesicles of Saccharomyces cerevisiae. Abe, M., Qadota, H., Hirata, A., Ohya, Y. J. Cell Biol. (2003)
- Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast. Peterson, J., Zheng, Y., Bender, L., Myers, A., Cerione, R., Bender, A. J. Cell Biol. (1994)
- A novel role for the mating type (MAT) locus in the maintenance of cell wall integrity in Saccharomyces cerevisiae. Verna, J., Ballester, R. Mol. Gen. Genet. (1999)
- Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase. Qadota, H., Python, C.P., Inoue, S.B., Arisawa, M., Anraku, Y., Zheng, Y., Watanabe, T., Levin, D.E., Ohya, Y. Science (1996)
- ROM7/BEM4 encodes a novel protein that interacts with the Rho1p small GTP-binding protein in Saccharomyces cerevisiae. Hirano, H., Tanaka, K., Ozaki, K., Imamura, H., Kohno, H., Hihara, T., Kameyama, T., Hotta, K., Arisawa, M., Watanabe, T., Qadota, H., Ohya, Y., Takai, Y. Mol. Cell. Biol. (1996)
- Pxl1p, a paxillin-like protein in Saccharomyces cerevisiae, may coordinate Cdc42p and Rho1p functions during polarized growth. Gao, X.D., Caviston, J.P., Tcheperegine, S.E., Bi, E. Mol. Biol. Cell (2004)
- Prenylation of Rho1p is required for activation of yeast 1, 3-beta-glucan synthase. Inoue, S.B., Qadota, H., Arisawa, M., Watanabe, T., Ohya, Y. J. Biol. Chem. (1999)
- Geranylgeranyltransferase I of Candida albicans: null mutants or enzyme inhibitors produce unexpected phenotypes. Kelly, R., Card, D., Register, E., Mazur, P., Kelly, T., Tanaka, K.I., Onishi, J., Williamson, J.M., Fan, H., Satoh, T., Kurtz, M. J. Bacteriol. (2000)
- The Rho-GAP Bem2p plays a GAP-independent role in the morphogenesis checkpoint. Marquitz, A.R., Harrison, J.C., Bose, I., Zyla, T.R., McMillan, J.N., Lew, D.J. EMBO J. (2002)
- Lrg1p Is a Rho1 GTPase-activating protein required for efficient cell fusion in yeast. Fitch, P.G., Gammie, A.E., Lee, D.J., de Candal, V.B., Rose, M.D. Genetics (2004)
- Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. Imamura, H., Tanaka, K., Hihara, T., Umikawa, M., Kamei, T., Takahashi, K., Sasaki, T., Takai, Y. EMBO J. (1997)
- The LIM domain-containing Dbm1 GTPase-activating protein is required for normal cellular morphogenesis in Saccharomyces cerevisiae. Chen, G.C., Zheng, L., Chan, C.S. Mol. Cell. Biol. (1996)
- Dissection of upstream regulatory components of the Rho1p effector, 1,3-beta-glucan synthase, in Saccharomyces cerevisiae. Sekiya-Kawasaki, M., Abe, M., Saka, A., Watanabe, D., Kono, K., Minemura-Asakawa, M., Ishihara, S., Watanabe, T., Ohya, Y. Genetics (2002)
- Lrg1p functions as a putative GTPase-activating protein in the Pkc1p-mediated cell integrity pathway in Saccharomyces cerevisiae. Lorberg, A., Schmitz, H.P., Jacoby, J.J., Heinisch, J.J. Mol. Genet. Genomics (2001)
- Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae. Yamochi, W., Tanaka, K., Nonaka, H., Maeda, A., Musha, T., Takai, Y. J. Cell Biol. (1994)
- Cloning of the RHO1 gene from Candida albicans and its regulation of beta-1,3-glucan synthesis. Kondoh, O., Tachibana, Y., Ohya, Y., Arisawa, M., Watanabe, T. J. Bacteriol. (1997)