Gene Review:
LY6D - lymphocyte antigen 6 complex, locus D
Homo sapiens
Synonyms:
E48, E48 antigen, Ly-6D, Lymphocyte antigen 6D
- A gain of novel tissue specificity in the human Ly-6 gene E48. Brakenhoff, R.H., van Dijk, M., Rood-Knippels, E.M., Snow, G.B. J. Immunol. (1997)
- Genetic reprogramming of tumor cells by zinc finger transcription factors. Blancafort, P., Chen, E.I., Gonzalez, B., Bergquist, S., Zijlstra, A., Guthy, D., Brachat, A., Brakenhoff, R.H., Quigley, J.P., Erdmann, D., Barbas, C.F. Proc. Natl. Acad. Sci. U.S.A. (2005)
- A 22-kd surface antigen detected by monoclonal antibody E 48 is exclusively expressed in stratified squamous and transitional epithelia. Quak, J.J., Balm, A.J., van Dongen, G.A., Brakkee, J.G., Scheper, R.J., Snow, G.B., Meijer, C.J. Am. J. Pathol. (1990)
- Use of monoclonal antibody E48 in diagnosing transitional cell carcinoma of urinary bladder. Torenbeek, R., Blomjous, C.E., Quak, J.J., Ybema, S., Meijer, C.J. J. Clin. Pathol. (1992)
- The human E48 antigen, highly homologous to the murine Ly-6 antigen ThB, is a GPI-anchored molecule apparently involved in keratinocyte cell-cell adhesion. Brakenhoff, R.H., Gerretsen, M., Knippels, E.M., van Dijk, M., van Essen, H., Weghuis, D.O., Sinke, R.J., Snow, G.B., van Dongen, G.A. J. Cell Biol. (1995)
- Clinical imaging of head and neck cancer with technetium-99m-labeled monoclonal antibody E48 IgG or F(ab')2. de Bree, R., Roos, J.C., Quak, J.J., den Hollander, W., van den Brekel, M.W., van der Wal, J.E., Tobi, H., Snow, G.B., van Dongen, G.A. J. Nucl. Med. (1994)
- The GPI-linked Ly-6 antigen E48 regulates expression levels of the FX enzyme and of E-selectin ligands on head and neck squamous carcinoma cells. Eshel, R., Zanin, A., Sagi-Assif, O., Meshel, T., Smorodinsky, N.I., Dwir, O., Alon, R., Brakenhoff, R., van Dongen, G., Witz, I.P. J. Biol. Chem. (2000)
- Biodistribution of radiolabeled monoclonal antibody E48 IgG and F(ab')2 in patients with head and neck cancer. de Bree, R., Roos, J.C., Quak, J.J., den Hollander, W., Wilhelm, A.J., van Lingen, A., Snow, G.B., Dongen, G.A. Clin. Cancer Res. (1995)
- Human cytochrome b5 requires residues E48 and E49 to stimulate the 17,20-lyase activity of cytochrome P450c17. Naffin-Olivos, J.L., Auchus, R.J. Biochemistry (2006)
- Radioimmunotherapy of human head and neck squamous cell carcinoma xenografts with 131I-labelled monoclonal antibody E48 IgG. Gerretsen, M., Schrijvers, A.H., van Walsum, M., Braakhuis, B.J., Quak, J.J., Meijer, C.J., Snow, G.B., van Dongen, G.A. Br. J. Cancer (1992)
- Construction and characterization of the chimeric monoclonal antibody E48 for therapy of head and neck cancer. Brakenhoff, R.H., van Gog, F.B., Looney, J.E., van Walsum, M., Snow, G.B., van Dongen, G.A. Cancer Immunol. Immunother. (1995)
- Characterization of the human Ly-6 antigens, the newly annotated member Ly-6K included, as molecular markers for head-and-neck squamous cell carcinoma. de Nooij-van Dalen, A.G., van Dongen, G.A., Smeets, S.J., Nieuwenhuis, E.J., Stigter-van Walsum, M., Snow, G.B., Brakenhoff, R.H. Int. J. Cancer (2003)
- Radioimmunoscintigraphy of head and neck cancer using 99mTc-labeled monoclonal antibody E48 F(ab')2. van Dongen, G.A., Leverstein, H., Roos, J.C., Quak, J.J., van den Brekel, M.W., van Lingen, A., Martens, H.J., Castelijns, J.A., Visser, G.W., Meijer, C.J. Cancer Res. (1992)
- Clinical significance of micrometastatic cells detected by E48 (Ly-6D) reverse transcription-polymerase chain reaction in bone marrow of head and neck cancer patients. Colnot, D.R., Nieuwenhuis, E.J., Kuik, D.J., Leemans, C.R., Dijkstra, J., Snow, G.B., van Dongen, G.A., Brakenhoff, R.H. Clin. Cancer Res. (2004)
- Evidence for a role of the monoclonal antibody E48 defined antigen in cell-cell adhesion in squamous epithelia and head and neck squamous cell carcinoma. Schrijvers, A.H., Gerretsen, M., Fritz, J.M., van Walsum, M., Quak, J.J., Snow, G.B., van Dongen, G.A. Exp. Cell Res. (1991)
- 186Re-labeled monoclonal antibody E48 immunoglobulin G-mediated therapy of human head and neck squamous cell carcinoma xenografts. Gerretsen, M., Visser, G.W., van Walsum, M., Meijer, C.J., Snow, G.B., van Dongen, G.A. Cancer Res. (1993)
- Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice. Folli, S., Westermann, P., Braichotte, D., Pèlegrin, A., Wagnières, G., van den Bergh, H., Mach, J.P. Cancer Res. (1994)
- Functional consequences of mutations in amino acid residues that stabilize calcium binding to the first epidermal growth factor homology domain of human protein C. Geng, J.P., Cheng, C.H., Castellino, F.J. Thromb. Haemost. (1996)
- Genomic structure and chromosomal localization of GML (GPI-anchored molecule-like protein), a gene induced by p53. Kimura, Y., Furuhata, T., Urano, T., Hirata, K., Nakamura, Y., Tokino, T. Genomics (1997)
- Identification and immunotherapeutic targeting of antigens induced by chemotherapy. Rubinfeld, B., Upadhyay, A., Clark, S.L., Fong, S.E., Smith, V., Koeppen, H., Ross, S., Polakis, P. Nat. Biotechnol. (2006)